珍珠烧伤膏治疗乳腺癌术后皮瓣坏死创面不愈的临床疗效观察
发布时间：2019-07-03 19:05
【摘要】：目的:观察珍珠烧伤膏在治疗乳腺癌术后皮瓣坏死创面不愈中促进愈合的疗效,寻找一种好的治疗创面不愈的方法。方法:病例来源于2009年06月—2016年12月期间就诊于吉林大学中日联谊医院乳腺外科的乳腺癌术后皮瓣坏死创面不愈的患者。按照随机原则把纳入的252例乳腺癌术后皮瓣坏死创面不愈的患者作为研究对象,均符合纳入及排除标准,使用随机数字表法按患者先后入院时间编号,治疗组为130人,对照组为122人。治疗组运用珍珠烧伤膏治疗乳腺癌术后皮瓣坏死创面不愈,对照组运用生理盐水纱布外敷。统计分析治疗组与对照组总体愈合情况。另外,探讨全身及局部因素对珍珠烧伤膏治疗乳腺癌术后皮瓣坏死创面不愈的影响。换药期间详细观察创面愈合及肉芽组织生长情况。结果:1、治疗组与对照组总体愈合率比较,差异具有统计学意义(p0.05)。2、60岁患者中治疗组与对照组愈合率比较,差异具有统计学意义(p0.05);≥60岁患者中治疗组与对照组愈合率比较,差异不具有统计学意义(p0.05)。3、糖尿病患者中治疗组与对照组愈合率比较,差异不具有统计学意义(p0.05);非糖尿病患者中治疗组与对照组愈合率比较,差异具有统计学意义(p0.05)。4、肥胖型患者中治疗组与对照组愈合率比较,差异具有统计学意义(p0.05);非肥胖型患者中治疗组与对照组愈合率比较,差异同样具有统计学意义(p0.05)。5、创面缺损大小≤5.0cm患者中治疗组与对照组愈合率比较,差异具有统计学意义(p0.05);创面缺损大小5.0cm患者中治疗组与对照组愈合率比较,差异不具有统计学意义(p0.05)。结论:1、珍珠烧伤膏治疗乳腺癌术后皮瓣坏死创面不愈能够提高总体愈合率。2、珍珠烧伤膏对治疗非老年及肥胖型患者乳腺癌术后皮瓣坏死创面不愈有效。3、针对患者乳腺癌术后出现皮瓣坏死创面缺损较大(宽度5.0cm)、为老年女性、糖尿病诊断明确,珍珠烧伤膏疗效不明显。
[Abstract]:Objective: to observe the effect of pearl burn ointment in the treatment of skin flap necrosis wound healing after breast cancer operation, and to find a good method to treat wound nonhealing. Methods: the case was from June 2009 to December 2016 in the breast surgery department of China-Japan United Hospital of Jilin University. According to the principle of randomization, 252 patients with unhealed skin flap after breast cancer surgery were enrolled in the study, all of which met the criteria of inclusion and exclusion. According to the admission time of the patients, 130 patients in the treatment group and 122 patients in the control group were enrolled in the random digital table method. The treatment group was treated with pearl burn ointment, while the control group was treated with saline gauze. The overall healing of the treatment group and the control group was statistically analyzed. In addition, to investigate the effect of whole body and local factors on the treatment of skin flap necrosis wound with pearl burn ointment after breast cancer surgery. Wound healing and granulation tissue growth were observed in detail during dressing change. Results: 1 there was significant difference in the overall healing rate between the treatment group and the control group (p0.05). 2, there was significant difference between the treatment group and the control group in the healing rate between the treatment group and the control group (p0.05). There was no significant difference in the healing rate between the treatment group and the control group (p0.05). 3. There was no significant difference in the healing rate between the treatment group and the control group (p0.05). There was significant difference in healing rate between treatment group and control group in non-diabetic patients (p0.05). 4. There was significant difference in healing rate between treatment group and control group in obese patients (p0.05). There was also significant difference in healing rate between treatment group and control group in non-obese patients (p0.05). 5. There was significant difference in healing rate between treatment group and control group in patients with wound defect size 鈮，
本文编号：2509602
[Abstract]:Objective: to observe the effect of pearl burn ointment in the treatment of skin flap necrosis wound healing after breast cancer operation, and to find a good method to treat wound nonhealing. Methods: the case was from June 2009 to December 2016 in the breast surgery department of China-Japan United Hospital of Jilin University. According to the principle of randomization, 252 patients with unhealed skin flap after breast cancer surgery were enrolled in the study, all of which met the criteria of inclusion and exclusion. According to the admission time of the patients, 130 patients in the treatment group and 122 patients in the control group were enrolled in the random digital table method. The treatment group was treated with pearl burn ointment, while the control group was treated with saline gauze. The overall healing of the treatment group and the control group was statistically analyzed. In addition, to investigate the effect of whole body and local factors on the treatment of skin flap necrosis wound with pearl burn ointment after breast cancer surgery. Wound healing and granulation tissue growth were observed in detail during dressing change. Results: 1 there was significant difference in the overall healing rate between the treatment group and the control group (p0.05). 2, there was significant difference between the treatment group and the control group in the healing rate between the treatment group and the control group (p0.05). There was no significant difference in the healing rate between the treatment group and the control group (p0.05). 3. There was no significant difference in the healing rate between the treatment group and the control group (p0.05). There was significant difference in healing rate between treatment group and control group in non-diabetic patients (p0.05). 4. There was significant difference in healing rate between treatment group and control group in obese patients (p0.05). There was also significant difference in healing rate between treatment group and control group in non-obese patients (p0.05). 5. There was significant difference in healing rate between treatment group and control group in patients with wound defect size 鈮，
本文编号：2509602
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