MSCT联合肿瘤标志物对肝内肿块型胆管细胞癌的诊断价值
发布时间：2019-07-05 06:25
【摘要】：目的:探讨MSCT联合肿瘤标志物(包括CA19-9、CA125、CEA、AFP)对肝内肿块型胆管细胞癌(IMCC)的诊断及鉴别诊断价值。方法:回顾性分析74例肝占位患者(包括34例IMCC和40例非IMCC患者)的影像及临床资料。总结、分析34例IMCC的CT表现;比较CT单独诊断IMCC及CT联合肿瘤标志物(CA19-9、CA125、CEA阳性,AFP阴性)诊断IMCC的准确率;进行肿瘤大小、强化程度与肿瘤标志物的相关性分析。结果:IMCC CT表现为形态不规则,平扫肿瘤均呈低密度,28例肿瘤内有囊变坏死区,6例体积较小者病灶内密度均匀。CT增强扫描动脉期肿瘤呈环状、网格状轻度强化者16例。门脉期和静脉期33例呈渐进性延迟强化,门脉受侵4例,所在肝叶萎缩8例,邻近肝包膜凹陷15例,肝门、腹膜后淋巴结转移16例。CT单独诊断IMCC的准确率为66.2%(49/74),CT联合肿瘤标志物的诊断准确率为83.8%(62/74),两者差异有统计学意义(P=0.000)。肿瘤大小、强化程度与肿瘤标志物的相关性无统计学意义(P0.05)。结论:IMCC的典型CT表现为动脉期轻度边缘环状强化,门脉期、静脉期呈渐进性强化;CT联合肿瘤标志物可以有效提高IMCC的诊断准确率;肿瘤大小、强化程度与肿瘤标志物无相关性。
[Abstract]:Objective: to evaluate the value of MSCT combined with tumor markers (including CA19-9,CA125,CEA,AFP) in the diagnosis and differential diagnosis of intrahepatic mass bile duct carcinoma (IMCC). Methods: the imaging and clinical data of 74 patients with liver space-occupying (including 34 patients with IMCC and 40 patients with non-IMCC) were analyzed retrospectively. The CT findings of 34 cases of IMCC were analyzed, the accuracy of CT in the diagnosis of IMCC and CT combined with tumor markers (CA19-9,CA125,CEA positive, AFP negative) was compared, and the correlation between tumor size, enhancement degree and tumor markers was analyzed. Results: IMCC CT showed irregular shape and low density on plain scan. 28 cases had cysts and necrotic areas, 6 cases had uniform density in 6 cases with smaller volume, 16 cases had annular tumors in arterial phase and 16 cases had mild enhancement in grid shape on CT enhanced scan. The portal vein phase and venous phase showed progressive delayed enhancement in 33 cases, portal vein invasion in 4 cases, lobar atrophy in 8 cases, adjacent hepatic capsule depression in 15 cases, hilar and retroperitoneal lymph node metastasis in 16 cases. The accuracy of CT alone in the diagnosis of IMCC was 66.2% (49 鈮，
本文编号：2510309
[Abstract]:Objective: to evaluate the value of MSCT combined with tumor markers (including CA19-9,CA125,CEA,AFP) in the diagnosis and differential diagnosis of intrahepatic mass bile duct carcinoma (IMCC). Methods: the imaging and clinical data of 74 patients with liver space-occupying (including 34 patients with IMCC and 40 patients with non-IMCC) were analyzed retrospectively. The CT findings of 34 cases of IMCC were analyzed, the accuracy of CT in the diagnosis of IMCC and CT combined with tumor markers (CA19-9,CA125,CEA positive, AFP negative) was compared, and the correlation between tumor size, enhancement degree and tumor markers was analyzed. Results: IMCC CT showed irregular shape and low density on plain scan. 28 cases had cysts and necrotic areas, 6 cases had uniform density in 6 cases with smaller volume, 16 cases had annular tumors in arterial phase and 16 cases had mild enhancement in grid shape on CT enhanced scan. The portal vein phase and venous phase showed progressive delayed enhancement in 33 cases, portal vein invasion in 4 cases, lobar atrophy in 8 cases, adjacent hepatic capsule depression in 15 cases, hilar and retroperitoneal lymph node metastasis in 16 cases. The accuracy of CT alone in the diagnosis of IMCC was 66.2% (49 鈮，
本文编号：2510309
本文链接：https://www.wllwen.com/yixuelunwen/zlx/2510309.html
