溃结灵Ⅳ号保留灌肠对大肠湿热型UC活动期患者FSTL1及FC影响的临床观察

发布时间：2017-12-28 17:25

本文关键词：溃结灵Ⅳ号保留灌肠对大肠湿热型UC活动期患者FSTL1及FC影响的临床观察　出处：《黑龙江中医药大学》2017年硕士论文　论文类型：学位论文

【摘要】：目的:观察溃结灵Ⅳ号保留灌肠对大肠湿热型UC活动期患者FSTL1及FC的影响方法:将符合标准的30例溃疡性结肠炎患者随机分为观察组与对照组,每组各15例。观察组给予溃结灵Ⅳ号保留灌肠,对照组患者给予美沙拉嗪灌肠剂灌肠,连续治疗4周后观察两组患者在临床症状、电子肠镜下黏膜变化情况以及血清FSTL1和粪便FC值。得出结果后,通过统计学分析并进行分析。结果:观察组总有效率93.33%,对照组总有效率为80.00%,且两组间差异具有统计学意义(p0.05)。治疗组在临床症状改善,肠镜下黏膜变化情况及FSTL1、FC指标均较对照组有明显改善。结论:1.溃结灵Ⅳ号保留灌肠在改善大肠湿热型UC活动期患者症状及肠镜下黏膜糜烂、水肿等具有显著疗效。2.溃结灵Ⅳ号保留灌肠能够降低大肠湿热型UC活动期患者的FSTL1及FC水平。
[Abstract]:Objective: To observe the effect of Kuijie Ling IV retention enema on FSTL1 and FC in UC active stage of large intestine damp heat. Methods: 30 patients with ulcerative colitis who met the standard were randomly divided into observation group and control group, 15 cases in each group. The observation group was given Kui Jie Ling IV retention enema. The control group was given mesalazine enema enema. After 4 weeks of treatment, the clinical symptoms, the changes of mucosal appearance under electronic colonoscopy and the serum FSTL1 and fecal FC value of the two groups were observed. After the result, through statistical analysis and analysis. Results: the total effective rate of the observation group was 93.33%, the total effective rate of the control group was 80%, and the difference between the two groups was statistically significant (P0.05). In the treatment group, the clinical symptoms were improved, the mucosal changes under the colonoscopy and the indexes of FSTL1 and FC were significantly improved. Conclusion: 1. kuijecling IV retention enema has a significant effect in improving the symptoms of the UC active phase of the large intestine and the intestinal mucosa erosion and edema under the enteroscope. 2. Kuijie Ling IV retention enema can reduce the level of FSTL1 and FC in the patients with UC active phase of the large intestine.
【学位授予单位】：黑龙江中医药大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R259

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