健脾温肾调瘿方治疗原发性甲减（脾肾阳虚证）的临床观察

发布时间：2017-12-28 18:01

本文关键词：健脾温肾调瘿方治疗原发性甲减（脾肾阳虚证）的临床观察　出处：《长春中医药大学》2016年硕士论文　论文类型：学位论文

【摘要】：目的:本课题总结导师朴春丽教授多年针对临床甲减所常用中药方剂的临床经验,自拟健脾温肾调瘿方对上述人群进行药物干预,寻求治疗临床甲减的有效途径。方法:采用随机对照法,按患者的就诊顺序随机分组,随机分为2组,其中治疗组30例,对照组30例,并给予相应的药物。患者均来源于长春中医药大学附属医院门诊病人。所有患者均符合中西医诊断标准及纳入标准。结果:健脾温肾调瘿方联合优甲乐治疗组与西药对照组对比统计学有显著性差异(P0.01),在改善指标上与西药对照组对比有统计学意义(P0.05)。在中医整体疗效上治疗组总有效率为93.33%,西药对照组总有效率为83.3%。经统计学对比分析后显示:健脾温肾调瘿方联合优甲乐治疗组与西药对照组组间对比均有显著性差异(P0.01)。治疗前后未发生明显的不良事件。结论:健脾温肾调瘿方治疗原发性甲减(脾肾阳虚证)临床疗效确切,能够显著改善生化指标,并且明显改善患者的中医临床症状,减少应用西药的副作用。临床可推行此方法,安全可行性较好。
[Abstract]:Objective: To summarize the clinical experience of Professor Pu Chunli, which is commonly used in clinical hypothyroidism, and to invigorate the spleen, warming kidney and regulating gall formula to intervene the above populations, and seek effective ways to treat clinical hypothyroidism. Methods: randomly divided into 2 groups randomly and randomly divided into 2 groups, 30 in the treatment group and 30 in the control group, and the corresponding drugs were given. All the patients were from the outpatient of the Affiliated Hospital of Changchun University of Traditional Chinese Medicine. All patients were in conformity with the standard of TCM and Western medicine. Results: there was a significant difference between Jianpi Wen Shen Tiao Ying Fang and you Jia Le treatment group compared with western medicine control group (P0.01), and there was a significant difference between the treatment group and the western medicine control group (P0.05). The total effective rate in the treatment group of Chinese medicine was 93.33%, and the total effective rate of the western medicine control group was 83.3%. After statistical analysis, the results showed that there were significant differences between the combination of Jianpi warming kidney gall gall side and the western medicine control group (P0.01). There were no obvious adverse events before and after the treatment. Conclusion: Jianpi warming kidney and regulating gall decoction is effective in treating primary hypothyroidism, spleen and kidney yang deficiency syndrome, which can significantly improve biochemical indexes, and significantly improve the clinical symptoms of Chinese medicine and reduce the side effects of Western medicine. This method can be carried out in clinical practice, and it is safe and feasible.
【学位授予单位】：长春中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R259

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