耳穴压丸配合辛芩颗粒治疗鼻鼽的临床疗效观察及证型相关性分析

发布时间：2017-12-28 18:41

本文关键词：耳穴压丸配合辛芩颗粒治疗鼻鼽的临床疗效观察及证型相关性分析　出处：《成都中医药大学》2016年硕士论文　论文类型：学位论文

【摘要】：目的：本研究根据耳穴理论和经络理论,运用耳穴压丸,通过外治法与内治法结合,旨在观察耳穴压丸治疗鼻鼽的临床疗效及安全性,探究耳穴压丸治疗鼻鼽的作用机理,力求寻找一种安全有效且容易为患者接受的治疗方法,并就其治疗效果与证型的相关性进行分析研究。方法：将符合纳入标准的60例患者根据随机数字表分为两组：治疗组(口服辛芩颗粒+耳穴压丸组),对照组(单纯口服辛芩颗粒)。两组分别治疗四周,并于治疗之前和治疗1、2周末,治疗第4周末进行采集并记录症状、体征积分。对所得数据进行统计和分析。结果：在疗效方面,治疗1周末治疗组总有效率为53.3%,对照组为28.6%,两组差异有统计学意义,但在改善鼻塞、喷嚏、流涕、鼻痒各鼻部症状方面,两组资料差异均无统计学意义。治疗2周末治疗组总有效率为66.7%,对照组为57.1%,两组差异无统计学意义。治疗4周末治疗组总有效率为70%,对照组为60.7%。两组受试者经治疗后症状体征均有改善,但试验组在疗效(改善鼻部症状和体征)方面效果优于对照组,可能是治疗组在对照组基础上加用了耳穴压丸,有补益肺气,扶正祛邪,摄涕止鼽的功效。各组对于鼻痒的改善均不明显。对于鼻塞、喷嚏、流涕症状的改善1周末时治疗组略优于对照组。治疗2周末、治疗4周末时治疗组与对照组在改善鼻部症状与体征疗效方面无统计学差异。结论：耳穴压丸与辛芩颗粒在改善鼻部症状及体征方面均有一定疗效,但对于鼻痒无明显改善。治疗1周末时,耳穴压丸联合辛芩颗粒使用其效果要优于单纯使用辛芩颗粒。治疗2周末及4周末时两组疗效相当。辛芩颗粒对于肺气虚寒及脾气虚弱患者的鼻鼽症状改善明显,中成药使用仍旧离不开中医辨证指导。
[Abstract]:Objective: This study is based on the theory and application of ear meridian theory, ear pressure pills, through external therapy combined with internal treatment, to observe the clinical efficacy and safety of ear pressure pill in the treatment of allergic rhinitis, explore the mechanism of ear pressure pill in the treatment of allergic rhinitis, in order to find a safe and effective and easy for the patient to receive treatment, to analyse and research the relationship between therapeutic effect and TCM syndrome types. Methods: 60 patients who met the inclusion criteria were divided into two groups according to the random number table: the treatment group (oral Xin Qin granule + auricular point pressing pill group), and the control group (only oral Xin Qin granule). The two groups were treated for four weeks, and before and after the 1 and 2 weeks of treatment, the symptoms and signs were recorded and recorded at the end of the fourth week. Statistics and analysis of the obtained data. Results: in terms of efficacy, 1 weeks of treatment, the total efficiency of treatment group was 53.3%, 28.6% in the control group, there was significant difference between two groups, but the improvement in nasal congestion, sneezing, runny nose, nasal itching, nasal symptoms, the difference of two groups were not statistically significant. The total effective rate of the treatment group was 66.7% at the end of the 2 week treatment group, and the control group was 57.1%. The difference between the two groups was not statistically significant. The total effective rate of the treatment group was 70% at the end of the 4 week treatment group and 60.7% in the control group. Two groups of subjects with symptoms and signs were improved after treatment, but the curative effect in the experimental group (improve nasal symptoms and signs) better than the control group, the treatment group in the control group may be based on the use of ear pressure pills, replenishing qi, Fuzhengquxie, Sheti Zhiqiu effect. The improvement of nasal itching in each group was not obvious. For nasal congestion, sneezing, runny nose symptoms improved after 1 week treatment group was slightly better than the control group. There was no statistical difference between the treatment group and the control group at the end of the 2 week and the 4 week of treatment in improving the symptoms and signs of the nose. Conclusion: the ear point pressing pill and Xin Qin granule have a certain effect in improving nasal symptoms and signs, but there is no obvious improvement on the nasal itching. At the end of the 1 week treatment, the effect of pressing pills of the auricular point combined with simutqin granules was better than the single use of simutqin granules. The treatment of the two groups was equivalent to the two groups at the end of the 2 and 4 weekends. Xinqin granule biqiu for symptoms of lung deficiency and spleen qi deficiency patients improved significantly, the use of Chinese patent medicines still cannot do without the guidance of tcm.
【学位授予单位】：成都中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R276.7

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