补肾活血调冲汤治疗肾虚血瘀型卵巢早衰的临床观察
本文关键词:补肾活血调冲汤治疗肾虚血瘀型卵巢早衰的临床观察 出处:《黑龙江中医药大学》2017年硕士论文 论文类型:学位论文
更多相关文章: 卵巢早衰 补肾活血调冲汤 肾虚血瘀 临床观察
【摘要】:目的:通过观察补肾活血调冲汤治疗肾虚血瘀型卵巢早衰的临床疗效,采用统计学软件进行分析,对总的临床疗效进行评价,为临床治疗卵巢早衰提供有效方剂及相关研究工作提供一定的思路。方法:本课题的研究运用自身治疗前后对照的方法,收集从2015年03月~2016年12月到黑龙江中医药大学附属第一医院妇科门诊就诊,符合纳入标准被诊断为肾虚血瘀型卵巢早衰的患者45例,嘱患者口服补肾活血调冲汤进行治疗,连续服用三个月经周期,然后观察患者治疗前与治疗后临床症状积分与病情程度的改善、血清FSH与E2数值的变化以及总疗效的情况。结果:患者经过治疗后,临床症状积分有明显下降;患者的潮热汗出、性欲低下、腰酸膝软等症状也有显著的改变;不同的病情程度都有一定的改善,且轻度患者的有效率明显高于中度和重度的患者;血清FSH的积分较治疗前明显下降,E2的水平比治疗前有所上升,均具有统计学意义(P0.05);患者的综合疗效结果:痊愈1例,占2.22%;显效18例,占40.00%;有效23例,占51.11%;无效3例,占6.67%;总有效率为93.33%。结论:补肾活血调冲汤对于肾虚血瘀型卵巢早衰患者的治疗,有很好的临床疗效,可以有效地缓解卵巢早衰引起的一系列临床症状,同时可以使血清中的FSH降低,升高体内的E2水平,中药治疗本病后期疗效稳定。
[Abstract]:Objective: To observe the clinical efficacy of Bushen Huoxue tune Chong Decoction in the treatment of premature ovarian failure with kidney deficiency and blood stasis by statistical software, and to evaluate the total clinical efficacy, so as to provide some ideas for effective treatment of premature ovarian failure and related research work. Methods: the study using self-control methods before and after treatment of the subject, collected from 2015 03 to December 2016 to the First Affiliated Hospital of Heilongjiang University Of Chinese Medicine gynecological clinic, 45 patients met the inclusion criteria were diagnosed with kidney deficiency and blood stasis type of premature ovarian failure, patients with BSHX Tiaochong decoction, taking three consecutive menstrual cycles. Then observe the patients before treatment and changes of clinical symptoms and the severity of disease, improve the serum FSH and E2 values after treatment and the total effect of the situation. Results: the patients after treatment, clinical symptom score decreased significantly; hot flashes sweating, low libido, soreness of waist and knee symptoms were also changed significantly; the different severity are improved, and the efficiency was significantly higher than that of patients with mild to moderate and severe patients; integral serum FSH than before treatment decreased E2 levels increased than before treatment, were statistically significant (P0.05); the comprehensive curative effect of the patients: 1 cases were cured, accounting for 2.22%; 18 cases were markedly effective, accounting for 40%; 23 cases were effective, accounting for 51.11%; 3 cases were ineffective, accounting for 6.67%; the total efficiency was 93.33%. Conclusion: Bushen Huoxue Soup for treatment of patients with kidney deficiency and blood stasis type of premature ovarian failure, have a good clinical effect, can effectively alleviate a series of clinical symptoms of premature ovarian failure, while the serum FSH decreased, increased the level of E2 in vivo, traditional Chinese medicine treatment of this disease stable post effect.
【学位授予单位】:黑龙江中医药大学
【学位级别】:硕士
【学位授予年份】:2017
【分类号】:R271.9
【参考文献】
相关期刊论文 前10条
1 庞勇;黄艳燕;;针灸治疗卵巢早衰疗效Meta分析[J];中医药临床杂志;2016年01期
2 肖静;;中西医结合治疗卵巢早衰45例[J];中国中医药现代远程教育;2015年19期
3 王志江;魏国栋;马思缇;;地黄多糖的化学和药理作用研究进展[J];中国实验方剂学杂志;2015年16期
4 李丹青;肖强兵;;巴戟天多糖通过p38 MAPK信号通路促间充质干细胞成骨分化的体外研究[J];中国中医骨伤科杂志;2015年05期
5 胡荣魁;谈勇;;夏桂成国医大师调治卵巢早衰经验探赜[J];江苏中医药;2015年05期
6 张雪;宋玉琴;杨雨婷;熊亮;彭成;谢晓芳;;益母草活血化瘀化学成分与药理作用研究进展[J];药物评价研究;2015年02期
7 安方玉;刘永琦;骆亚莉;李应东;刘雪松;张齐;蔡路路;孙丽姣;;当归不同有效部位对高原低氧模型小鼠免疫功能的影响[J];中国中医药信息杂志;2015年02期
8 肖清丰;付蓓;周慧芳;;补肾祛瘀针法治疗卵巢早衰的临床观察[J];湖北中医杂志;2015年01期
9 李茜西;吕德欣;;卵巢早衰的病因及治疗研究进展[J];中国医药导报;2014年30期
10 苏洁;陈素红;吕圭源;牟秀华;方慧;;杜仲及菟丝子对肾阳虚大鼠生殖力及性激素的影响[J];浙江中医药大学学报;2014年09期
相关博士学位论文 前1条
1 赵志艺;卵巢早衰的遗传学病因分析和PTEN抑制剂对卵巢的作用及其安全性研究[D];山东大学;2013年
,本文编号:1347767
本文链接:https://www.wllwen.com/zhongyixuelunwen/1347767.html