黄芪柏术汤促进热毒炽盛型低位肛痈术后创面愈合的临床疗效观察

发布时间：2017-12-31 02:13

本文关键词：黄芪柏术汤促进热毒炽盛型低位肛痈术后创面愈合的临床疗效观察　出处：《福建中医药大学》2017年硕士论文　论文类型：学位论文

【摘要】：目的:探讨热毒炽盛型低位肛周脓肿患者术后,口服黄芪柏术汤治疗后对创面分泌物、创面疼痛、创面肉芽组织生长情况、创面愈合情况、创面愈合时间及总疗效等方面的影响。方法:在临床上选择符合纳入标准的低位肛周脓肿术后患者60例,随机分为两组,按随机数字表随机分为对照组和治疗组各30例。两组在手术前后采用相同的常规治疗基础上,治疗组于术后第1天予口服黄芪柏术汤,日一剂,分两次服,连服一周;对照组予常规治疗。观察两组患者术后第1天、第7天、第14天、第21天创面渗液及分泌物、创面疼痛程度,创面肉芽组织生长情况等进行评分并记录数据。在术后第1天、术后第7天、第14天、第21天分别测量两组患者创面长度、宽度,比较创面愈合时间及术后2个月总疗效。结果:入选的60例患者,收集时无病例脱落。治疗前将两组病例的性别、年龄、病程分布、创面分泌物、创面疼痛程度、创面肉芽组织生长情况等进行比较,差异均无统计学意义,治疗前基线一致,具有可比性。研究结果分析如下:(1)创面渗液及分泌物情况:两组术后第7、14、21天创面分泌物情况比较均呈显著性差异(P0.05),治疗组明显优于对照组。(2)创面肉芽组织生长情况:两组术后第7、14、21天肉芽组织生长情况比较均呈显著性差异(P0.05),治疗组明显优于对照组。(3)创面长度、宽度和创面愈合时间:两组术后第7天,创面长度、宽度比较无统计学意义(P0.05)。两组术后第14、21天,创面长度、宽度比较有统计学意义(P0.05),治疗组优于对照组。治疗组平均创面愈合时间(26.73±2.448)天,对照组平均创面愈合时间(32.23±4.312)天,创面愈合时间比较存在显著性差异(P0.05),治疗组平均愈合时间明显短于对照组。(4)创面疼痛情况:两组术后第7、14、21天创面疼痛情况比较均无统计学意义(P0.05)。(5)总体疗效比较:术后2个月观察两组总疗效,创面愈合率100%,创面上皮完全覆盖,疤痕坚实。治疗组有效率93.33%,对照组有效率83.33%,两组对比统计学无显著性差异(P0.05)。结论:黄芪柏术汤能够有效地减轻术后并发症,可明显减少创面渗液及分泌物、促进创面肉芽组织生长,加快创面愈合,缩短愈合周期等,从而提高患者生活质量。且用药过程中未出现不良反应,临床值得推广应用。
[Abstract]:Objective: to investigate the effect of Huangqi Peshuzhu decoction on wound secretion, wound pain, granulation tissue growth and wound healing after operation in patients with low perianal abscess with incandescent heat toxin. Methods: 60 patients with low perianal abscess were randomly divided into two groups. On the basis of the same routine treatment before and after operation, the treatment group was given orally Astragalus Boxuzhu decoction on the first day after operation, once a day, divided into two groups. For a week; The patients in the control group were treated with routine therapy. The wound exudates and secretions were observed on the 1st, 7th, 14th and 21st day after operation, and the degree of wound pain was observed. The wound granulation tissue growth was scored and the data were recorded. The wound length and width were measured on the first day, the 7th day, the 14th day and the 21st day after operation. Results: there were 60 patients who were selected, no cases fell off at the time of collection. Before treatment, the sex, age, course of disease, wound secretion of the two groups were compared. The degree of wound pain, granulation tissue growth and so on were compared, the differences were not statistically significant, the baseline before treatment was the same. The results of the study were as follows: 1) wound exudation and secretion: there was significant difference between the two groups on the 1st day after operation (P 0.05). The granulation tissue growth in the treatment group was significantly better than that in the control group (P 0.05): the granulation tissue growth of the treatment group was significantly higher than that of the control group (P 0.05). The length, width and healing time of wound in the treatment group were significantly better than those in the control group (P < 0.05): the length and width of the wound were not significantly different between the two groups on the 7th day after operation (P 0.05). After 21 days, the length and width of wound were significantly higher in the treatment group than in the control group, and the average wound healing time in the treatment group was 26.73 卤2.448 days. In the control group, the average wound healing time was 32.23 卤4.312 days, and there was significant difference in wound healing time (P 0.05). The average healing time in the treatment group was significantly shorter than that in the control group. There was no significant difference in the total curative effect between the two groups 2 months after operation, the wound healing rate was 100 and the wound epithelium was completely covered. The effective rate of the treatment group was 93.33 and that of the control group was 83.33%. There was no significant difference between the two groups (P 0.05). Conclusion: Huangqi Baizhu decoction can effectively reduce postoperative complications, can significantly reduce wound effusion and secretion, promote the growth of wound granulation tissue. In order to improve the quality of life of the patients, the wound healing was accelerated and the healing cycle was shortened. There were no adverse reactions in the course of medication, so it is worth popularizing and applying clinically.
【学位授予单位】：福建中医药大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R266

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