大连市区女童性早熟与中医体质的相关性研究
本文关键词:大连市区女童性早熟与中医体质的相关性研究 出处:《大连医科大学》2016年硕士论文 论文类型:学位论文
更多相关文章: 性早熟 女童 大连 中医体质 相关因素 统计分析
【摘要】:研究目的和意义中医学认为体质和疾病的发生关系密切。故本课题研究大连市区性早熟女童的中医体质特点,通过对体质的相关研究及性早熟女童与正常女童调查结果的对照研究,分析性早熟女童中医体质的分布规律,中医体质与年龄、体重指数、相关理化检查、中医证候、影响因素等的相关性,旨在探讨体质与疾病的相关性、不同个体体质形成机理与规律及如何纠正体质的偏颇,为治疗和预防本病提供客观指标与新的思路。从根本上预防性早熟的发生,为广大儿童健康成长保驾护航。研究方法采用横断面研究方法,对正常女童及符合纳入标准的性早熟女童同期进行调查问卷判定其中医体质,并对性早熟发病的可能相关影响因素进行问卷,据此筛查可能的致病因素。同时对性早熟女童进行中医证候调查问卷及中医四诊,据此判断其中医症候并收集临床指标等相关资料。运用现代统计方法,对这些资料进行统计学分析:对性早熟女童不同体质类型与中医证型、乳房分期的关系进行卡方检验,不同体质类型与体重指数、子宫容积、卵巢容积进行Kruskal-Wallis检验,对可能引起女童性早熟的16个影响因素进行logistic回归分析。探讨正常女童及性早熟女童体质分布情况、体质与患儿临床资料的相关性,发病的危险因素,偏颇体质成因、与发病的相关性及偏颇体质的干预方法,从而指导如何治未病。研究结果1.正常女童体质分布以均衡质为主,占57.14%;性早熟女童体质分布以湿性体质(湿热质和痰湿质)为主,共占29.58%。2.对全部性早熟女童中医证型进行统计,阴虚火旺型(52.67%)、肝郁化火型(30.54%)、痰湿内蕴型(16.79%)。3.不同体质的性早熟女童证型分布有统计学差异,均衡质患者以阴虚火旺型为主;4.对各项资料与体质分类进行统计学分析后得出:无统计学差异的是乳房分期、体重指数、子宫容积、卵巢容积。有统计学差异的是发病年龄和骨龄指数,湿热质以大年龄组为主,气郁质骨龄指数最高。5.对可能引起女童性早熟的16个影响因素调查后,进行logistic回归分析,结果P值小于显著性0.05并且优势比OR的估计值在95%的上下限之间的影响因素为母亲初潮年龄偏早、母孕期保胎、母孕期心绪不佳、亮灯睡觉、服用营养滋补品、食用含激素食品、家庭不和谐、喜爱看情感电视,故以上可能是造成大连市区女童性早熟的影响因素。结论1.大连市区正常女童体质分布以均衡质为主,性早熟女童体质分布以湿性体质(湿热质和痰湿质)为主。2.不同体质性早熟女童中医证型存在显著差异,均衡质患者以阴虚火旺型为主。3.对各项资料与体质分类进行统计学分析后得出:无统计学差异的是乳房分期、体重指数、子宫容积、卵巢容积。有统计学差异的为发病年龄和骨龄指数,大年龄组以湿热质为主,气郁质骨龄指数最高。4.母亲初潮年龄偏早、母孕期保胎、母孕期心绪不佳、亮灯睡觉、服用营养滋补品、食用含激素食品、家庭不和谐、喜爱看情感电视等,可能是造成大连市区女童性早熟的影响因素。
[Abstract]:The purpose and significance of research in TCM Constitution and diseases have close relationship. So the research of Dalian city's precocious girls Chinese physical characteristics, the control study on fitness related research and precocious girls and normal girls survey results, analysis of the distribution regularity of early Cougar children physical medicine, TCM Constitution and age. Body mass index, physical and chemical examination, TCM syndrome, correlation factors, designed to investigate the correlation between physical fitness and disease, different individual physical formation mechanism and rule and how to correct the biased constitution, to provide ideas and new objective index for the treatment and prevention of this disease. It can prevent the onset of puberty, growth escort for the majority of children's health. Research methods by using cross-sectional study, the normal girls and met the inclusion criteria of precocious girls questionnaire was used to determine the same period The constitution of traditional Chinese medicine, and the onset of precocious puberty may be related factors questionnaire, pathogenic factors accordingly. At the same time of screening may precocious girls TCM syndrome questionnaire and TCM diagnosis, judge their symptoms and collect relevant information of clinical indicators. Using modern statistical methods, statistical analysis of these data: precocious girls of different constitution types and TCM syndrome type, the chi square test breast staging, different body types and body mass index, uterine volume, ovarian volume of Kruskal-Wallis test, can cause the girls 16 factors of precocious puberty were analyzed by logistic regression analysis. To explore the normal girls and precocious girls physical distribution. The correlation between clinical data and physical fitness of children, the risk factors, the biased constitution causes, intervention methods and the incidence of correlation and biased constitution, How to guide the treatment of disease. The results of 1. normal girls physical distribution to balance quality based, accounting for 57.14%; precocious girls physical distribution to wet body (damp heat and phlegm), accounted for 29.58%.2. of all the precocious girls of TCM, yinxuhuowang (52.67%), liver Yu fire type (30.54%), phlegm dampness type (16.79%).3. in different physical precocious girls syndrome distribution had significant difference, the equilibrium quality with Yinxu Huowang type; 4. of the information and the constitution classification of statistical analysis showed that no statistically significant difference is breast stage, body mass index. Volume of uterus, ovarian volume. There were significant differences in the onset age and bone age index, damp heat by age group, Qi quality index is the highest.5. of bone age may cause investigation of girls 16 factors of sexual precocity, logistic regression analysis. If the P value is less than 0.05 and significant advantages than the estimated value of OR factors between the upper 95% of the mothers menarche age early pregnancy, miscarriage, pregnancy, bad mood, light sleep, taking nutritional supplements, eating food containing hormones, family discord, enjoy watching TV is so emotional, more than likely influence factors of Dalian urban girls with precocious puberty. Conclusion constitution of Dalian city 1. normal girls in the distribution of equilibrium matter, precocious girls physical distribution in wet body (damp heat and phlegm dampness) there are significant differences in.2. in different physical precocious girls TCM syndrome type, balanced type with Yinxu Huowang type.3. statistical analysis of the data and classification of constitution that is no significant difference between breast stage, body mass index, uterine volume, ovarian volume. There were significant differences in the age of onset and bone age index, Age group of damp heat, qi stagnation, bone age index and the highest.4. mother age early menarche, pregnancy, miscarriage, pregnancy, bad mood, light sleep, taking nutritional supplements, eating food containing hormones, family discord, like Emotional TV, may be caused by the factors of Dalian city. The girls with precocious puberty
【学位授予单位】:大连医科大学
【学位级别】:硕士
【学位授予年份】:2016
【分类号】:R272
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