温肾活血法改善不孕症患者子宫内膜容受性的前瞻性队列研究

发布时间：2018-01-02 08:48

本文关键词：温肾活血法改善不孕症患者子宫内膜容受性的前瞻性队列研究　出处：《辽宁中医杂志》2017年10期 　论文类型：期刊论文

【摘要】：目的:评价温肾活血法改善不孕症患者子宫内膜容受性的疗效。方法:选取2015年3月—2016年1月在本院门诊就诊的子宫内膜容受性不足的不孕症患者100例,采用前瞻性队列研究的方法,根据是否接受中医温肾活血疗法将纳入的患者分为治疗组(52例)及对照组(48例),治疗组接受温肾活血法治疗及西医基础治疗,对照组只接受西医基础治疗。通过问卷调查,门诊复查,电话询问等方式进行随访,以子宫内膜厚度、类型、子宫动脉PI值及RI值、血清E2、P水平及妊娠率为观察指标,观察两组子宫内膜容受性改善的效果。结果:HCG日及黄体中期治疗组子宫内膜厚度明显高于对照组(P0.05),治疗组A型内膜多于对照组(P0.05)。治疗后两组子宫动脉PI值及RI值均明显降低(P0.05),但治疗组下降幅度优于对照组(P0.05);两组血清E2、P水平较治疗前均升高(P0.05),组间比较E2、P水平差异有显著性(P0.05)。治疗结束后治疗组妊娠率则显著高于对照组(P0.05)。结论:温肾活血法能有效改善不孕症患者子宫内膜容受性,提高不孕症患者的妊娠率。
[Abstract]:Objective: to improve the curative effect of infertility patients with endometrial receptivity evaluation of Wen Shen Huoxue. Methods: 100 patients with infertility from March 2015 to January 2016 the endometrial receptivity in the outpatient department of the lack of cases, using the method of prospective cohort study, according to whether to accept Chinese medicine wenshenhuoxue therapy will be included in the patients were divided into treatment group (52 cases) and control group (48 cases), the treatment group received warm kidney and activating blood therapy and Western medicine therapy, while the control group only received conventional therapy. Through the questionnaire, outpatient review, telephone inquiries in the follow-up to the endometrial thickness, uterine artery type, PI value and RI value. Serum E2, P levels and pregnancy rate were observed, observe two groups of endometrial receptivity improved. Results: HCG day and mid luteal endometrial thickness in treatment group was significantly higher than the control group (P0.05 group), the treatment of type A endometrial multi In the control group (P0.05). The two groups after treatment of uterine artery PI value and RI value were significantly decreased (P0.05), but the treatment group decreased than the control group (P0.05); serum E2 P levels of two groups, compared with before treatment were significantly increased (P0.05), E2 group, there was significant difference in P levels (P0.05). After treatment, the pregnancy rate of treatment group was significantly higher than that of control group (P0.05). Conclusion: Yishen Huoxue method can improve the endometrial receptivity of patients with infertility, improve the pregnancy rate of infertility patients.

【作者单位】：湘潭市中心医院中西医结合科;湘潭市中心医院生殖中心;
【分类号】：R271.14
【正文快照】： 不孕症发病率逐年上升,对患者生殖健康及家庭幸福造成严重危害。辅助生殖技术的发明运用使不孕症的治疗获得了突破性进展,但仍有约半数患者不能成功妊娠[1]。子宫内膜容受性不足是胚胎种植失败的主要原因[2],且已成为制约辅助生殖技术获取更高妊娠率的瓶颈。千百年来,中医药在

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