重庆市非酒精性脂肪性肝病中医证型规律及特点的研究

发布时间：2018-01-03 10:00

本文关键词：重庆市非酒精性脂肪性肝病中医证型规律及特点的研究　出处：《重庆医学》2017年18期 　论文类型：期刊论文

【摘要】：目的探讨非酒精性脂肪性肝病(NAFLD))中医证型分布规律及其与相关临床指标的相关性。方法调查重庆市1 950例NAFLD患者一般情况、中医四诊、生化及CT结果,分析中医证型分布规律及其与生化、CT的相关性。结果 1 950例患者中,湿热蕴结、湿浊内停、肝郁脾虚、痰瘀互结、肝肾阴虚证分别占36.62%、27.69%、19.38%、10.10%、6.21%;不同证型的年龄差异有统计学意义(P0.05);重度脂肪肝肝肾阴虚证(35.54%)最多,其次为痰瘀互结证(15.23%);湿热蕴结证丙氨酸转氨酶(ALT)、天冬氨酸氨基转移酶(AST)水平较高;肝肾阴虚证空腹血糖(FBG)水平较高;肝郁脾虚证总胆固醇(TC)、三酰甘油(TG)、FBG水平较低,差异有统计学意义(P0.05)。结论 NAFLD患者以湿热蕴结证分布最多,肝肾阴虚证重度脂肪肝比例最高,不同辩证分型可能对临床指标及疾病转归有重要作用。
[Abstract]:Objective to investigate the nonalcoholic fatty liver disease (NAFLD)) correlation between TCM syndromes distribution and its correlation with clinical parameters. Methods Survey in Chongqing City, 1950 cases of NAFLD patients in general, TCM, biochemical and CT results, analysis of TCM syndrome type distribution and biochemical, CT correlation. Results in 1950 cases, dampness heat accumulation within the stop, liver stagnation and spleen deficiency, phlegm and blood stasis, liver and kidney yin deficiency accounted for 36.62%, 27.69%, 19.38%, 10.10%, 6.21%; there is significant difference in age of different syndromes (P0.05); severe fatty liver and liver kidney yin deficiency syndrome (35.54%), followed by phlegm and blood stasis (15.23%); rdhs alanine aminotransferase (ALT), aspartate aminotransferase (AST) level is higher; Yin deficiency of liver and kidney. Fasting blood glucose (FBG) level is higher; liver stagnation and spleen deficiency of total cholesterol (TC), triglyceride (TG), three FBG level is low, the difference was statistically significant (P0.05). Conclusion NAFLD patients with damp heat syndrome distribution, liver kidney yin deficiency syndrome of severe fatty liver in the highest proportion, different dialectical type of clinical parameters and prognosis of the disease has an important role.

【作者单位】：重庆市中医院肝病科;重庆市永川区中医院风湿科;重庆市涪陵区中医院脾胃科;重庆市三峡中心医院感染科;成都关怀医院中医科;重庆市黔江区中医院感染科;
【基金】：重庆市卫生和计划生育委员会中医药科技项目(zy201402048)
【分类号】：R259
【正文快照】： 6.重庆市黔江区中医院感染科409000)非酒精性脂肪性肝病(non-alcoholic fatty liver disease,NAFLD)是与胰岛素抵抗和遗传易感性密切相关的获得性代谢应激性肝损伤[1],已成为我国第一大慢性肝脏疾病。因地区、调查对象不同,NAFLD的患病率不一。本病起病隐匿,缺乏特效药,中医治

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