五运六气禀赋对儿童过敏性紫癜发病的相关性研究

发布时间：2018-01-04 16:00

本文关键词：五运六气禀赋对儿童过敏性紫癜发病的相关性研究　出处：《广州中医药大学》2017年硕士论文　论文类型：学位论文

【摘要】：目的:本文通过将运气禀赋体质与过敏性紫癜相结合,以五行生克制化和治未病思想作为防治理论,探讨运气禀赋因素对过敏性紫癜发病、发展的影响,从而寻找广州中医药大学第一附属医院儿科住院病人中过敏性紫癜的病人与非过敏性紫癜患儿的运气禀赋差异特点,以期发现该病致病的危险因素或保护因素,更好地规避风险、指导治疗。方法:收集广州中医药大学第一附属医院儿科住院部的全部患儿,出生日期在1996至2010年,其中过敏性紫癜患儿共350例,以此作为实验组,并以同年龄段在该科室住院的非过敏性紫癜患儿为对照组,共计约14418例。采用回顾性病例对照的研究方法,分别比较两组之间的各个禀赋因素和运气禀赋体质的差异,推测发生过敏性紫癜可能存在的易感或保护因素。结果:在五运当中,分别对两组十天干进行比较,结果提示两者无统计学意义(P=0.087);对两组合并后的五行进行比较,既分别比较水行、木行、火行、土行、金行五行,结果提示两者在木运、金运和土运间具有统计学意义(P0.05);以阴阳属性为原则,对两者进行归纳比较,结果提示其在阴属性、中(土)间具有统计学意义(P0.05)。在六气当中,分别对两组十二地支进行比较,结果提示阳明燥金司天(P=0.0079)、太阳寒水司天(P=0.0058)、太阴湿土司天(P=0.0058)及太阳寒水在泉(P=0.0092)具有统计学意义;而合并后的三阴三阳(P=0.451)及阴阳属性(P=0.425)无统计学意义。而在运气禀赋因素的协同作用下,对两组运气禀赋进行比较,结果提示太金-太阳寒水(P=0.0000)、少木-少阳相火(P:=0.0001)、少土-太阴湿土(P=0.0000)、少土-太阳寒水(P=0.0001)具有统计学意义。结论:过敏性紫癜的易感因素包括阳明燥金司天、太阳寒水司天、岁运-中(土)、岁运-土行和太金-太阳寒水;保护因素包括太阴湿土司天、太阳寒水在泉、岁运-阴、岁运-木行、岁运-金行、少木-少阳相火、少土-太阴湿土和少土-太阳寒水,提示紫癜患儿的体质具有体质偏阳、脾肾亏虚和禀赋逆四时生长规律等特点。
[Abstract]:Objective: to explore the influence of luck endowment factors on the pathogenesis and development of Henoch-Schonlein purpura (Hpura) by combining luck endowment with allergic purpura and taking the thought of "Wuxingsheng restraint" and "preventing and treating diseases" as the prevention and treatment theory. In order to find out the risk factors or protective factors of allergic purpura in pediatric inpatients in the first affiliated Hospital of Guangzhou University of traditional Chinese Medicine, the difference of luck between the patients with Henoch-Schonlein purpura and children with non-Henoch-Schonlein purpura was found. Methods: all the children in the Department of Pediatrics of the first affiliated Hospital of Guangzhou University of traditional Chinese Medicine were collected from 1996 to 2010. Among them 350 cases of Henoch-Schonlein purpura were used as experimental group and non-Henoch-Schonlein purpura children who were hospitalized in the same age department as control group. A total of 14418 cases were studied by retrospective case-control study to compare the differences of the endowment factors and the physique of luck between the two groups. The results showed that there was no significant difference between the two groups in ten days, the results showed that there was no statistical significance between the two groups. The comparison of the five elements of the two groups after the merger, namely water row, wood line, fire line, soil line, gold line five elements, the results suggest that the two groups in wood transport, gold transport and soil transport between the statistical significance of P0.05; Based on the principle of yin and yang, the results show that there is statistical significance between them in the Yin attribute and the middle (earth). In the six Qi, the two groups of 12 ground branches are compared respectively. The results suggested that Yangming dryness Jinsitiandao (P0. 0079) and sun cold water (P0. 0058). There was statistical significance between Taiyin and wet Tusi (P0. 0058) and solar cold water (P0. 0092). However, there was no statistical significance between the combined three yin and three yang (P _ (0.451)) and the attribute of Yin and Yang (P _ (0.425)). However, the luck endowment of the two groups was compared under the synergistic effect of the factors of luck endowment. The results suggest that Taijin-Sun cold water (P0. 00000), Shaomu-Shaoyang phase fire (P0. 0001), and soil-too wet soil (P0. 0000). Conclusion: the susceptible factors of allergic purpura include Yangming dryness Jinsitian, solar cold water days, years of transport-middle (soil). Years of transport-soil line and Taijin-sun cold water; Protective factors include too wet toast days, the sun cold water in spring, year transport-yin, year-transport-wood line, year-transport-gold line, less wood-less sun fire, less soil-too wet soil and less earth-sun cold water. It is suggested that the constitution of the children with purpura has the characteristics of yang deficiency of spleen and kidney deficiency of spleen and kidney and growth law of endowment.
【学位授予单位】：广州中医药大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R272

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