不同频率电针结合中药治疗肾虚型多囊卵巢综合征的临床观察

发布时间：2018-01-05 09:57

本文关键词：不同频率电针结合中药治疗肾虚型多囊卵巢综合征的临床观察　出处：《湖北中医药大学》2017年硕士论文　论文类型：学位论文

【摘要】：目的:以肾虚型多囊卵巢综合征患者为临床研究对象,比较经低频电针+中药、高频电针+中药与单纯中药治疗后,三组患者的临床疗效,为肾虚型多囊卵巢综合征患者的治疗方案提供最佳的实践依据。方法:将符合纳入标准的60例患者按照随机数字表法分为3组:中药组(对照组)共20例,予中药自拟补肾活血汤加减治疗;针药结合组共40例,其中低频电针结合中药组(治疗组A)20例,服用补肾活血汤加减的同时予以低频电针(频率2HZ)治疗;高频电针结合中药组(治疗组B)20例,服用补肾活血汤加减同时予以高频电针(频率为50HZ)治疗;治疗组选取穴位:气海、关元、大赫(双)、子宫(双)、血海(双)、足三里(双)、丰隆(双)、三阴交(双)、太冲(双)、合谷(双)、肾俞(双)、次毼(双)进行针刺,并连接电针,共连续治疗3个月经周期,比较三组治疗前后临床症状及体征的改善情况及卵泡刺激素(FSH)、促黄体生成素(LH)、LH/FSH、雌二醇(E2)、睾酮(T)、体质量及体重指数(BMI)等指标的变化,评估三组患者的临床疗效,运用SPSS统计软件对相关指标进行分析比较。结果:(1)治疗组A的治愈率为20%,总有效率为90%;治疗组B的治愈率为15%,总有效率为85%;中药组的治愈率为5%,总有效率为70%;治疗组疗效均较中药组好,均具有统计学意义(P0.05),两针药结合组在总体疗效上无明显差别(P0.05)。(2)血清性激素水平比较:三组治疗后,血清LH、LH/FSH、T值均明显下降,治疗前后有差异,均有统计学意义(均P0.05);治疗前后的FSH、E2值无明显差异(P0.05)。与中药组相比:两针药结合组的LH、LH/FSH、T值分别与其比较均有明显的差异(P0.05);两针药结合组之间比较,治疗后LH、LH/FSH,治疗组A较治疗组B降低更甚,差异具有统计学意义(P0.05);治疗后T值,治疗组B较治疗组A降低更甚,差异有统计学意义(P0.05)。(3)体质量、BMI比较:治疗后三组患者体质量及BMI均下降;两针药结合组分别与中药组比较,体质量、BMI前后差值有统计学意义(P0.05);两针药结合组相比,体质量及BMI前后的差值,治疗组B高于治疗组A,有统计学意义(P0.05)。结论:(1)电针联合中药对肾虚型PCOS的疗效优于仅使用中药组。(2)电针联合中药能够降低肥胖相关的指数。两针药结合组其体质量及BMI均明显下降,与中药组比较具有统计学意义(P0.05)。(3)电针联合中药可以明显改善性激素含量。两针药结合组其LH、LH/FSH、T值均明显降低,与中药组比较有统计学意义(P0.05)。(4)不同频率电针有不同的试验效果:本试验在性激素如LH、LH/FSH等改善方面,低频电针效果优于高频电针;高频电针比低频电针能更好的改善性激素T值及肥胖相关指数。
[Abstract]:Objective: to compare the clinical effects of low frequency electroacupuncture Chinese medicine, high frequency electroacupuncture Chinese medicine and simple Chinese medicine on the patients with polycystic ovary syndrome of kidney deficiency type. Methods: 60 patients with polycystic ovary syndrome were divided into 3 groups according to random digital table: 20 cases in Chinese medicine group (control group). Traditional Chinese medicine self-made tonifying kidney and activating blood decoction treatment; There were 40 cases in the combination group of acupuncture and medicine, of which 20 cases were treated with low frequency electroacupuncture combined with traditional Chinese medicine (treatment group, 20 cases), which were treated with Bushen Huoxue decoction and low frequency electroacupuncture (2HZ). High frequency electroacupuncture combined with traditional Chinese medicine group (treatment group, 20 cases, taking Bu Shen Huoxue decoction, at the same time high frequency electroacupuncture (frequency is 50 HZ) treatment; The treatment group selected acupoints: Qihai, Guan Yuan, Dahe (Shuangli, uterus, Xuehai (Shuangli), Zusanli (Shuangli), Fenglong (Shuangli, Sanyinjiao, Shuangzong, Taichong), Hegu (Shuangli, Shenshu). The patients were treated with acupuncture combined with electroacupuncture for 3 consecutive menstrual cycles. The improvement of clinical symptoms and signs and follicle stimulating hormone FSHs were compared before and after treatment. The changes of luteinizing hormone (LHG) LH / FSHE, estradiol estradiol (E2N), testosterone (TX), body mass index (BMI) and body mass index (BMI) were evaluated in order to evaluate the clinical efficacy of the three groups. Results the cure rate of treatment group A was 20 and the total effective rate was 90. The cure rate of treatment group B was 15 and the total effective rate was 85. The cure rate of TCM group was 5 and the total effective rate was 70. The curative effect of the treatment group was better than that of the traditional Chinese medicine group, which had statistical significance (P0.05). There was no significant difference in the overall curative effect between the two acupuncture and medicine combination group (P 0.05). Comparison of serum sex hormone levels: after treatment, the serum LHH / FSHT decreased significantly in the three groups. There was significant difference before and after treatment (P 0.05). There was no significant difference in E _ 2 between the two groups before and after treatment. Compared with the traditional Chinese medicine group, the LHH / FSH of the combined acupuncture and medicine group was higher than that of the traditional Chinese medicine group. T values were significantly different from those of them (P 0.05). After the treatment, the LHN LH / FSHS in the treatment group A was significantly lower than that in the treatment group B, and the difference was statistically significant (P 0.05). After treatment, the T value of treatment group B was significantly lower than that of treatment group A, and the difference was statistically significant. Compared with the traditional Chinese medicine group, the difference of BMI between the two acupuncture and medicine combination groups was statistically significant (P 0.05). The difference of body weight and BMI before and after treatment group B was higher than that of treatment group A. Conclusion the curative effect of electroacupuncture combined with traditional Chinese medicine on PCOS of kidney deficiency type is better than that of traditional Chinese medicine group only. Electroacupuncture combined with traditional Chinese medicine can reduce the obesity related index. The body weight and BMI of the two acupuncture and medicine combination group were significantly decreased. Compared with the traditional Chinese medicine group, electroacupuncture combined with traditional Chinese medicine can obviously improve the content of sex hormone, and the LHH / FSHT value of the two acupuncture combined group is obviously lower than that of the traditional Chinese medicine group. Compared with the traditional Chinese medicine group, there were significant differences in the effect of different frequency electroacupuncture: in the improvement of sex hormones such as LHH / FSH. The effect of low frequency electroacupuncture is better than that of high frequency electroacupuncture. High frequency electroacupuncture can improve sex hormone T value and obesity related index better than low frequency electroacupuncture.
【学位授予单位】：湖北中医药大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R246.3

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