熄风化湿方对腹泻型肠易激综合征患者的影响

发布时间：2018-01-05 10:27

本文关键词：熄风化湿方对腹泻型肠易激综合征患者的影响　出处：《中国现代医学杂志》2017年20期 　论文类型：期刊论文

【摘要】：目的探究熄风化湿方对腹泻型肠易激综合征患者的影响。方法选取2013年6月-2016年6月该院收治的122例腹泻型肠易激综合征患者为研究对象,采用随机数表法分为对照组和观察组,各61例,分别给予马来酸曲美布汀和熄风化湿方治疗。对比临床疗效和治疗前后血清五羟色胺、肠黏膜细胞因子水平。结果观察组和对照组患者的临床总有效率分别为95.07%(58/61)和73.76%(45/61),治疗后血清五羟色胺水平分别为(53.27±16.94)和(84.93±28.72)ng/ml,观察组患者治疗后肿瘤坏死因子α、白介素6及白介素10水平分别为(12.11±2.53)、(9.66±2.54)和(26.52±7.63)ng/L,对照组为(18.63±3.82)、(15.73±6.48)和(12.46±5.81)ng/L,两组比较差异有统计学意义(P0.05)。结论熄风化湿方治疗腹泻型肠易激综合征患者临床疗效佳,能改善肠动力紊乱,抑制肠道氧化应激反应。
[Abstract]:Objective to investigate the effect of Xifeng Huashi recipe on diarrhea irritable bowel syndrome. Methods 122 patients with diarrhea irritable bowel syndrome were selected from June 2013 to June 2016. The patients were divided into control group (61 cases) and observation group (61 cases) by random table method, which were treated with trimebutine maleate and Xifeng Huazhui prescription respectively. The clinical effect and serum serotonin before and after treatment were compared. Results the total effective rates of the observation group and the control group were 95.07 / 58 / 61) and 73.76g / 45 / 61, respectively. The serum serotonin levels after treatment were 53.27 卤16.94 and 84.93 卤28.72 ng / ml, respectively. The levels of IL-6 and IL-10 were 12.11 卤2.53 and 9.66 卤2.54, respectively, and 26.52 卤7.63 ng / L, respectively. The control group was 18.63 卤3.82 (15.73 卤6.48) and 12.46 卤5.81 ng / L respectively. Conclusion Xifeng Huashi prescription is effective in treating diarrhea irritable bowel syndrome, it can improve intestinal motility disorder and inhibit intestinal oxidative stress reaction.
【作者单位】：贵州省遵义市中医院;
【基金】：贵州省遵义市科技计划项目[No:遵市科合社字(2014)45号]
【分类号】：R259
【正文快照】： 肠易激综合征临床表现为腹部不适、腹痛、排便习惯改变等,发病机制复杂,其中腹泻型是最常见的表1两组临床疗效比较[n=61,例(%)]组别治愈显效有效无效总有效率观察组10(16.39)30(49.18)18(29.50)3(4.93)58(95.07)对照组5(8.19)15(24.59)25(40.98)16(26.24)45(73.76)类型[1-2]

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