补肾疏肝法治疗男性更年期综合征肾虚肝郁证疗效观察

发布时间：2018-01-05 23:01

本文关键词：补肾疏肝法治疗男性更年期综合征肾虚肝郁证疗效观察　出处：《光明中医》2017年07期 　论文类型：期刊论文

【摘要】：目的观察补肾疏肝法治疗男性更年期综合征肾虚肝郁证的临床疗效。方法 86例男性更年期综合征肾虚肝郁证患者按就诊顺序随机分为观察组和对照组各43例,观察组以补肾疏肝法治疗,予六味地黄汤合逍遥汤加减,每日1剂内服;对照组口服十一酸睾酮胶囊80mg/次,2次/日,1月后减为40mg/次,2次/日,舍曲林25 mg/次,2次/日。两组均以3个月为一个疗程。观察临床治疗效果及治疗前后PADAM评分变化情况。结果观察组总有效率为90.70%,对照组总有效率为76.74%,观察组疗效优于对照组(P0.05);治疗后两组PADAM各症状评分均降低(P0.01),且观察组在PADAM各症状评分变化上优于对照组(P0.05)。结论补肾疏肝法能够有效治疗肾虚肝郁型男性更年期综合征。
[Abstract]:Objective to observe the clinical effect of tonifying the kidney and soothing the liver in treating male climacteric syndrome with kidney deficiency and liver depression. 86 cases of male climacteric syndrome with kidney deficiency and liver depression were randomly divided into observation group (n = 43) and control group (n = 43). The observation group was treated with the method of tonifying the kidney and soothing the liver, and was treated with Liuwei Dihuang decoction and Xiaoyao decoction, 1 dose per day; In the control group, 80 mg testosterone undecanoate capsules were given orally twice a day, then reduced to 40 mg / d and 25 mg / d after January. Two times a day. The two groups were treated with 3 months as a course of treatment. The clinical effect and the changes of PADAM score before and after treatment were observed. Results the total effective rate of the observation group was 90.70%. The total effective rate of the control group was 76.744.The curative effect of the observation group was better than that of the control group (P 0.05). After treatment, the scores of each symptom of PADAM in both groups were decreased (P 0.01). The observation group was superior to the control group in the change of PADAM symptom score (P 0.05). Conclusion the method of tonifying the kidney and soothing the liver can effectively treat the male climacteric syndrome with kidney deficiency and liver depression.
【作者单位】：广东省东莞市人民医院中医科;
【基金】：东莞市医疗卫生科技计划项目(No.201610515000930)
【分类号】：R277.5
【正文快照】： 男性更年期综合征(PADAM)是常见于中老年男性的一组临床症候群,表现为神经功能紊乱、易疲劳、抑郁、易怒、失眠、性欲减退、勃起功能障碍等[1,2]。多由雄激素水平下降或雄激素受体异常引起,临床上以补充睾酮为常规疗法,并根据症状加用抗抑郁药或调整植物神经功能药物。由于药

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