进行性斑状色素减少症的反射式共聚焦激光扫描显微镜辅助诊断及中医体质研究

发布时间：2018-01-06 01:01

本文关键词：进行性斑状色素减少症的反射式共聚焦激光扫描显微镜辅助诊断及中医体质研究　出处：《南京中医药大学》2017年硕士论文　论文类型：学位论文

【摘要】：研究目的:总结进行性斑状色素减少症的临床表现,并运用反射式共聚焦激光显微镜辅助进行性斑状色素减少症的诊断,总结归纳进行性斑状色素减少症皮损在反射式激光共聚焦显微镜下的图像特征。分析进行性斑状色素减少症患者的中医体质类型,探索可能发病因素与中医体质之间是否存在科学规律,从而充实进行性斑状色素减少症的中医方面内容,为疾病的中医药诊断治疗提供基础。研究方法:本研究共纳入30例符合进行性斑状色素减少症诊断标准的患者。对30例纳入的进行性斑状色素减少症患者进行真菌镜检、伍氏灯和共聚焦扫描显微镜检查辅助诊断。登记患者一般情况、现病史资料,填写中医体质分类表和皮肤病生活质量调查表,对所有皮损进行拍照。研究结果:进行性斑状色素减少症好发于青年人,男女未见差异。圆形或者椭圆形淡白斑沿身体正中线两侧成网状分布,背部、腹部与腰部是发病率最高的几个部位。IV皮肤,皮肤油腻,出汗多,有既往痤疮史的患者多见。伍氏灯皮损区下均可见点状红色荧光,红色荧光密度低于自身痤疮皮损区。进行性斑状色素减少症在RCM下表现具有特异性:基底细胞环大致完整,色素减退。研究结论:RCM能辅助诊断进行性斑状色素减少症,在RCM下与白癜风易鉴别。进行性斑状色素减少症对患者的影响轻微。进行性斑状色素减少症患者中医体质类型主要见于湿热质、气虚质、和阴虚质。进行性斑状色素减少症患者中医体质类型的分布与年龄、性别、运动量无关联。进行性斑状色素减少症患者中医体质类型的分布与患者出汗量、肤色深浅有关联。
[Abstract]:Objective: To summarize the clinical manifestations of progressive macular hypomelanosis, and using a reflective confocal laser microscope assisted progressive macular hypomelanosis diagnosis, summarized macular pigment reduced image feature in reflective laser confocal microscope in lesions. Analysis of macular pigment reduction in patients with TCM type of constitution and to explore the possible existence of scientific laws between risk factors and TCM Constitution, so as to enrich of macular pigment reduce TCM aspects of disease, and provide basis for Chinese medicine diagnosis and treatment of diseases. Methods: This study included 30 patients with progressive macular hypomelanosis patients. The diagnostic criteria of 30 cases included the progressive macular hypomelanosis patients with microscopic fungi, Wu light wood and confocal scanning microscopy examination diagnosis. The general condition of the patient registration, now Medical records, fill in the constitution of TCM classification and dermatology quality of life questionnaire, all lesions were pictures. Results: progressive macular hypomelanosis occurs in young men and women, there was no difference. Round or oval pale white spots along the body midline on both sides of network distribution, back, abdomen and waist is the incidence of several parts the highest.IV skin, oily skin, sweating, a previous history of acne patients see more. Both punctate red fluorescence under the lamp of five family lesions, red fluorescence density lower than their acne lesions area. For macular pigment reduce symptoms with specificity in RCM: basal cell ring largely intact, hypopigmentation. Conclusion: RCM can aid in the diagnosis of progressive macular hypomelanosis, RCM in vitiligo and easy to identify. Progressive macular hypomelanosis on patients with mild influence. The macular pigment reduction In patients with TCM type of constitution mainly in the damp heat, Qi deficiency, and yin deficiency. Macular pigment reduce distribution and age, TCM type of constitution in patients with gender, no correlation between the amount of exercise. For macular pigment reduction in patients with TCM Constitution Types and the distribution of patients is related to the amount of sweat, skin deep.

【学位授予单位】：南京中医药大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R275.9

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