中国中医科学院广安门医院心内科治疗冠心病合并非瓣膜性房颤组方规律分析

发布时间：2018-01-07 13:16

本文关键词：中国中医科学院广安门医院心内科治疗冠心病合并非瓣膜性房颤组方规律分析　出处：《北京中医药》2017年03期 　论文类型：期刊论文

【摘要】：目的分析中国中医科学院广安门医院心内科治疗冠心病合并非瓣膜性房颤患者的用药特点及组方规律。方法收集2012年7月—2015年7月228例冠心病合并非瓣膜性房颤住院患者的临床资料,基于中医传承辅助平台V2.5软件进行统计分析。结果治疗冠心病合并非瓣膜性房颤共涉及方剂408首,包含药物309种。将支持度设置为61,置信度设置为0.6,得到常用药物的组合模式24种,得到关联规则13条。设置相关度为8,惩罚度为4,基于复杂网络熵聚类的核心组合38种,基于熵层次聚类的治疗冠心病合并非瓣膜性房颤的新方组合19个。结论中国中医科学院广安门心内科治疗冠心病合并非瓣膜性房颤以益气养阴为主,辅以活血化瘀、健脾祛湿;在此基础上通过复杂网络熵聚类分析得出新方组合19个,有待临床的进一步验证。
[Abstract]:Objective to analyze the clinical characteristics and prescription of cardiology in the treatment of coronary heart disease complicated with non-valvular atrial fibrillation in Guanganmen Hospital, Chinese Academy of traditional Chinese Medicine. Methods from July 2012 to July 2015, 228 cases of coronary heart disease were collected. Clinical data of inpatients with non-valvular atrial fibrillation. Results the treatment of coronary heart disease with non-valvular atrial fibrillation involved 408 prescriptions, including 309 kinds of drugs. The support degree was set to 61. The confidence degree is set to 0.6, 24 kinds of combination modes of common drugs are obtained, and 13 rules of association are obtained. The set correlation degree is 8, the penalty degree is 4, and the core combination based on complex network entropy clustering is 38 kinds. There are 19 new prescriptions for the treatment of coronary heart disease with non-valvular atrial fibrillation based on entropy hierarchical clustering. Conclusion the main treatment of coronary heart disease with non-valvular atrial fibrillation is to nourish qi and nourish yin in the treatment of coronary heart disease with non-valvular atrial fibrillation. Auxiliary to promote blood circulation and remove blood stasis, invigorate spleen and remove dampness; On this basis, 19 new combinations are obtained by entropy clustering analysis of complex networks, which need further clinical verification.
【作者单位】：中国中医科学院广安门医院南区;中国中医科学院广安门医院;北京中医药大学;
【基金】：国家中医药管理局行业专项(201207001) 十二五重点领域研究专项(zz0808005)
【分类号】：R259
【正文快照】： 心房颤动(房颤),指心房无序除极,正常生理电活动丧失,导致心房无有效收缩,是最严重的心房电活动紊乱,可以增加中风和死亡风险,其发病率随年龄的增加而增加[1]。冠状动脉粥样硬化性心脏病(冠心病)指冠状动脉粥样硬化使血管腔狭窄或阻塞,或因冠状动脉功能性改变(痉挛)导致心肌缺

【相似文献】