督脉经埋线治疗胃食管反流病的临床研究

发布时间：2018-01-07 22:19

本文关键词：督脉经埋线治疗胃食管反流病的临床研究　出处：《南京中医药大学》2017年硕士论文　论文类型：学位论文

【摘要】：目的:通过客观对比分析治疗前后胃食管反流病症状改善情况,评价督脉经埋线疗法对胃食管反流病的有效性。通过临床研究,进一步探讨埋线法治疗胃食管反流病的技术操作方法,为形成可推广应用的方法提供依据。方法:将符合研究标准的50例胃食管反流病患者随机分成治疗组与对照组各25例。治疗组予以督脉经埋线治疗,对照组服用由江苏济川制药有限公司生产的雷贝拉唑肠溶胶囊。以六周为一个疗程,观察一个疗程后两组患者的症状改善情况。以RDQ、胃食管反流病生活质量自评量表、SAS、SDS、GERDQ量表为评价指标,进行治疗前与治疗后、组间与组内临床疗效的比较。结果:1.治疗组患者显效13例,有效9例,无效3例;对照组显效6例,有效10例,无效9例;治疗组总有效率达88%,对照组总有效率为64%,差异具有统计学意义(P0.05);治疗组显效率为52%,对照组显效率为24%,差异具有统计学意义(P0.05)。说明治疗组疗效优于对照组,且对于患者症状改善程度更为明显。2.治疗组治疗后RDQ评分与治疗前对比,差异具有统计学意义(P0.05),说明督脉经埋线疗法对GERD治疗有效;对照组治疗后RDQ评分与治疗前对比,差异具有统计学意义(P0.05),说明口服雷贝拉唑对GERD治疗有效。3.治疗后两组RDQ、SAS、SDS、GERD-HRQL量表评分均显著降低(P0.05),治疗组治疗后量表评分明显低于对照组(P0.05),说明督脉经埋线疗法与口服雷贝拉唑相比,更能改善GERD患者的症状、体征和焦虑、抑郁状态以及生活质量的影响。结论:督脉经埋线治疗胃食管反流病疗效确切,优于西药治疗组。督脉经埋线能调整督脉气机升降,不仅对GERD患者的反酸、烧心、非心源性胸痛、反食等临床症状有很好的疗效,而且对于患者的焦虑,抑郁状态以及生活质量也有明显的改善。值得在临床上作为一项治疗GERD的新技术推广和应用。
[Abstract]:Objective: to analyze the improvement of gastroesophageal reflux disease (GERD) symptoms before and after treatment, and to evaluate the effectiveness of du meridian catgut embedding therapy for gastroesophageal reflux disease (GERD). To further explore the technique of embedding thread in the treatment of gastroesophageal reflux disease (GERD). Methods: 50 patients with gastroesophageal reflux disease were randomly divided into treatment group (n = 25) and control group (n = 25). The control group was treated with Rabeprazole enteric-coated capsule produced by Jiangsu Jichuan Pharmaceutical Co., Ltd. Six weeks as a course of treatment were used to observe the improvement of symptoms in the two groups after a course of treatment. RDQ was used. The quality of life (QOL) of gastroesophageal reflux disease (GERDQ) was evaluated by SASS-SDS+ GERDQ before and after treatment. Results 1. In the treatment group, there were 13 cases of remarkable effect, 9 cases of effective and 3 cases of failure. In the control group, 6 cases were effective, 10 cases were effective and 9 cases were ineffective. The total effective rate in the treatment group was 888.The total effective rate in the control group was 64. The difference was statistically significant (P 0.05). The effective rate of treatment group was 52 and that of control group was 24. The difference was statistically significant (P 0.05). The result showed that the effect of treatment group was better than that of control group. Treatment group after treatment RDQ score compared with before treatment, the difference was statistically significant (P0.05). The results showed that du meridian catgut embedding therapy was effective in the treatment of GERD. The RDQ scores of the control group after treatment were significantly different from those before treatment (P 0.05), indicating that oral rabeprazole was effective in the treatment of GERD. 3. After treatment, the two groups were treated with GERD. The scores of GERD-HRQL in the treatment group were significantly lower than those in the control group (P 0.05). Compared with oral rabeprazole, du meridian catgut embedding therapy can improve the symptoms, signs and anxiety of patients with GERD. Conclusion: the effect of embedding thread on gastroesophageal reflux disease is more effective than that of western medicine group. Not only for GERD patients with acid, heartburn, non-cardiogenic chest pain, anti-eating and other clinical symptoms have a good effect, but also for patients with anxiety. Depression and quality of life are also significantly improved, which is worthy of clinical application as a new technique for the treatment of GERD.
【学位授予单位】：南京中医药大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R246.1

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