穴位埋线与毫针刺治疗慢性疲劳综合征（肝郁脾虚型）临床对比观察

发布时间：2018-01-08 12:23

本文关键词：穴位埋线与毫针刺治疗慢性疲劳综合征（肝郁脾虚型）临床对比观察　出处：《湖南中医药大学》2016年硕士论文　论文类型：学位论文

【摘要】：目的:观察和比较穴位埋线与毫针刺治疗慢性疲劳综合征肝郁脾虚型患者的临床疗效与作用特点,并初步探讨其可能的作用机制,为临床应用提供客观依据。方法:将符合纳入标准的60例患者随机分为A组和B组,每组各30例。A组用穴位埋线,B组用毫针刺治疗。两组患者均选取肝俞、足三里、膈俞为第一组穴,脾俞、三阴交、胆俞为第二组穴,两组穴位交替应用。A组每隔10天埋线1次,共治疗4次;B组连续治疗8天,休息2天为1个治疗周期,共治疗4个周期。治疗前后用疲劳量表(FS-14)、疲劳症状积分量表、肝郁脾虚证候积分量表,分别对疲劳主症、疲劳兼症、中医症候三个主观指标进行评价,并抽取静脉血,用化学发光法检测客观指标即两组患者外周血血清中皮质醇含量。结果:1.治疗后,两组患者的FS-14评分较治疗前均有下降,差异有显著统计学意义(P0.01);A组较B组下降更明显,差异有统计学意义(P0.05)。2.治疗后,两组患者的疲劳症状积分量表评分较治疗前均有明显下降,差异有显著统计学意义(P0.01);A组与B组比较,差异不明显(P0.05)。3.治疗后,两组患者的肝郁脾虚证候积分量表评分较治疗前下降,差异有显著统计学意义(P0.01);但两组比较,无明显差异(P0.05)。4.治疗后两组总疗效差异无统计学意义(P0.05)。5.治疗后,两组患者血清皮质醇含量较治疗前有明显增高,差异有显著统计学意义(P0.01);两组间差异不明显,无统计学意义(P0.05)。结论:穴位埋线和毫针剌治疗CFS肝郁脾虚型都有明显效果,能显著改善患者的疲劳主症、兼症及肝郁脾虚症状,但穴位埋线对改善疲劳主症有明显的优势,而且治疗次数少,时间成本低,临床可优先选用。同时,两者都能显著升高CFS肝郁脾虚型患者血清中皮质醇的含量,说明其作用机制都可能与改善神经内分泌系统中的HPA轴功能有密切关系,值得进一步研究。
[Abstract]:Objective: to observe and compare the clinical effect and characteristics of acupoint catgut embedding and millimeter acupuncture in treating chronic fatigue syndrome patients with liver depression and spleen deficiency, and to explore its possible mechanism. Methods: 60 patients who met the inclusion criteria were randomly divided into group A and group B with 30 cases in each group. Two groups of patients were selected Gangshu, Zusanli, Geshu as the first point, spleen Yu, Sanyinjiao, Danshu as the second point, and the two groups were alternately treated with catgut embedding once every 10 days. A total of 4 times of treatment; Group B was treated continuously for 8 days, rest for 2 days for a treatment cycle, a total of 4 cycles. Before and after treatment, fatigue scale FS-14, fatigue symptom scale, liver stagnation and spleen deficiency syndrome integral scale. The main symptoms of fatigue, fatigue and symptoms, TCM symptoms of the evaluation of three subjective indicators, and the extraction of venous blood. Chemiluminescence method was used to detect the content of cortisol in peripheral blood of the two groups. Results: 1. After treatment, the FS-14 scores of the two groups were lower than those before treatment. The difference was statistically significant (P 0.01). Group A than group B more significant decline, the difference was statistically significant (P 0.05). After treatment, the two groups of patients' fatigue symptom scale scores were significantly lower than before treatment. The difference was statistically significant (P 0.01). There was no significant difference between group A and group B. after treatment, the score of liver depression and spleen deficiency syndrome in two groups was lower than that before treatment, and the difference was statistically significant (P 0.01). However, there was no significant difference between the two groups (P 0.05). 4. There was no significant difference in the total curative effect between the two groups after treatment. The serum cortisol content in the two groups was significantly higher than that before treatment, and the difference was statistically significant (P 0.01). There was no significant difference between the two groups (P 0.05). Conclusion: the treatment of CFS liver stagnation and spleen deficiency type by acupuncture at acupoint and acupuncture has obvious effect, and can significantly improve the main fatigue of patients. Both symptoms and liver stagnation and spleen deficiency symptoms, but acupoint embedding has obvious advantages in improving the main fatigue syndrome, and less times of treatment, low time cost, clinical can be selected first. At the same time. Both of them could significantly increase the content of cortisol in the serum of CFS patients with liver stagnation and spleen deficiency, indicating that the mechanism may be closely related to the improvement of HPA axis function in the neuroendocrine system, which is worthy of further study.
【学位授予单位】：湖南中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R246

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