大椎刺络放血治疗活动期类风湿性关节炎的临床研究

发布时间：2018-01-09 20:21

本文关键词：大椎刺络放血治疗活动期类风湿性关节炎的临床研究　出处：《河南中医药大学》2016年硕士论文　论文类型：学位论文

【摘要】：目的:观察大椎刺络放血治疗活动期类风湿性关节炎的临床疗效及安全性,论证运用特效穴-大椎穴刺络放血治疗活动期类风湿性关节炎的有效性,进而探索一种新的有效治疗本病的中医外治疗法。方法:按照纳入标准和排除标准选取60例活动期类风湿性关节炎患者,将其随机分为治疗组和对照组各30例。治疗组给予大椎刺络放血结合传统针刺治疗,对照组给予传统针刺治疗,连续治疗15天。比较试验开始时和结束时的中医证候积分,主要症状、体征,ESR、CRP,生命体征,血、尿常规及肝、肾功能。监测试验中可能出现的不良反应,及时处理,随时记录。试验结束后,进行疗效评定,并进行随访,随访时间为30天。结果:1.疾病总疗效比较:治疗组总有效率为93.33%,明显优于对照组的80.00%(P0.05)。中医证候疗效比较:治疗组总有效率为90.00%,明显优于对照组的76.67%(P0.05)。2.中医证候积分比较:两组组内治疗前后比较均有显著性差异(均P0.05);组间治疗后比较除屈伸不利一项差异不显著外(P0.05),余各项组间比较差异均显著(均P0.05)。两组的主要症状、体征及ESR、CRP比较:两组组内治疗前后及组间治疗后比较,均有显著性差异(均P0.05)。3.安全性评价:两组均未发生不良事件,且两组治疗前后的生命体征,血、尿常规及肝、肾功能均无异常。4.复发率比较:治疗组的复发率为10.00%,明显优于对照组的33.33%(P0.05)。结论:1.大椎刺络放血治疗活动期类风湿性关节炎有效率高,疗效确切。2.大椎刺络放血可明显改善活动期类风湿性关节炎患者的中医证候,主要症状、体征和ESR、CRP水平。3.大椎刺络放血在治疗活动期类风湿性关节炎过程中安全无不良反应。
[Abstract]:Objective: to observe the clinical efficacy and safety of Dazhui pricking bloodletting in treating active rheumatoid arthritis (RA), and to demonstrate the effectiveness of the treatment of active rheumatoid arthritis (RA) by using special acupoint and Dazhui acupoint pricking bloodletting to treat active rheumatoid arthritis (RA). Methods: 60 patients with active rheumatoid arthritis were selected according to the inclusion criteria and exclusion criteria. It was randomly divided into treatment group (30 cases) and control group (30 cases). The treatment group was treated with Dazhui prickle bloodletting combined with traditional acupuncture, while the control group was treated with traditional acupuncture. After 15 consecutive days of treatment, the scores of TCM syndromes, main symptoms and signs at the beginning and end of the trial were compared with those of ESR-CRP, vital signs, blood, urine routine and liver. Renal function. Monitoring of possible adverse reactions in the trial, timely treatment, record at any time. After the end of the trial, the efficacy was evaluated and followed up. The follow-up time was 30 days. Results: 1. Comparison of the total curative effect of the disease: the total effective rate of the treatment group was 93.33%. Compared with the control group, the total effective rate of the treatment group was 90.00%. Comparison of TCM syndrome scores: there were significant differences between the two groups before and after treatment (all P 0.05); After treatment, there was no significant difference between the two groups except flexion and extension disadvantage (P0.05). The main symptoms, physical signs and ESR of the two groups were significantly different (all P0.05). Comparison of CRP: there were significant differences between the two groups before and after treatment (P0.05. 3). Safety evaluation: there were no adverse events in both groups. And the two groups before and after treatment of vital signs, blood, urine routine, liver, kidney function were not abnormal .4.The recurrence rate: the treatment group recurrence rate was 10.00%. It is obviously superior to the control group (33.33, P 0.05). Conclusion: 1. The effective rate of Dazhui prickle in treating active rheumatoid arthritis is high. Dazhui puncture bleeding can significantly improve the active stage of rheumatoid arthritis patients with traditional Chinese medicine syndromes, main symptoms, signs and ESR. CRP level .3.Dazhui prickle bleeding in the treatment of active rheumatoid arthritis safe and no adverse reactions.
【学位授予单位】：河南中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R246.1

【相似文献】