补中益气汤合通窍活血汤治疗气虚血瘀型老年高血压病的临床观察

发布时间：2018-01-10 00:14

本文关键词：补中益气汤合通窍活血汤治疗气虚血瘀型老年高血压病的临床观察　出处：《山东中医药大学》2016年硕士论文　论文类型：学位论文

【摘要】：目的:观察在补中益气汤合通窍活血汤的干预下,1、2级老年原发性高血压患者(气虚血瘀型)的临床疗效、安全性及对患者生活质量的影响,以期为气虚血瘀型1、2级老年原发性高血压病患者的治疗提供新方法。方法:选取符合纳入标准的高血压病患者70例,随机将患者分至观察组和对照组,两组病例数均为35例。观察组在服用硝苯地平控释片30mg、每天一次的基础上给予中药补中益气汤合通窍活血汤加减治疗;对照组仅服用硝苯地平控释片30mg、每天一次,两组治疗周期均为4周。于治疗前后观察患者的一般情况、血、尿和大便常规、肝肾功能、诊室血压、动态血压、患者症候与体征变化情况,以及评估两组患者治疗前后生活质量,并进行统计学处理。结果:四周后,观察组患者诊室血压及动态血压较对照组均有明显降低(P0.05),证候积分亦有显著下降(P0.01);生活质量改善方面,观察组明显优于对照组(P0.05)。两组患者治疗前后一般情况、血、尿和大便常规、肝肾功能均未见明显异常。治疗过程中,两组患者均未出现严重不良反应或其他恶性突发状况。结论:中药补中益气汤合通窍活血汤可明显降低气虚血瘀型1、2级老年原发性高血压病患者血压值,改善患者临床症状、体征及生活质量,总体治疗有效率高,用药安全可靠,值得临床推广。
[Abstract]:Objective: To observe the Buzhong Yiqi Decoction and Tongqiaohuoxue Decoction intervention, 1,2 level in patients with senile primary hypertension (Qi deficiency and blood stasis type) clinical efficacy, safety and impact on quality of life of patients, in order to Qi deficiency and blood stasis 1,2 level in elderly patients with hypertension in the treatment to provide a new way. Methods: selected 70 hypertensive patients met the inclusion criteria were randomly assigned patients to treatment group and control group, two groups of cases were 35 cases. In the observation group taking Nifedipine Controlled Release Tablets 30mg once a day, based on the given Huoxue Decoction in the treatment of traditional Chinese medicine Buzhong Yiqi Decoction Tongqiao; control group received Nifedipine Controlled Release Tablets 30mg. Once a day, the treatment period was 4 weeks. The two groups were observed before and after treatment in general, patients with blood, urine and stool routine, liver and kidney function, consulting room, blood pressure, ambulatory blood pressure, body symptom and syndrome changes, and Evaluation of two groups before and after treatment the quality of life, and the data were analyzed statistically. Results: after four weeks, observe the blood pressure and blood pressure in patients with dynamic consulting room were significantly lower than the control group (P0.05), symptom scores significantly decreased (P0.01); improvement of quality of life, the observation group was significantly better than the control group (P0.05) before and after. Two groups of patients in general, blood, urine and stool routine, liver and kidney function had no obvious abnormalities. During the treatment, serious adverse reactions or other malignant emergencies were not found in two groups. Conclusion: Buzhong Yiqi Decoction and Tongqiaohuoxue decoction can significantly reduce the 1,2 level of qi deficiency and blood stasis syndrome in elderly primary hypertension patients disease of blood pressure, improve clinical symptoms, signs and the quality of life, the overall effective rate of the treatment, the medication is safe and reliable, worthy of promotion.

【学位授予单位】：山东中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R259

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