董氏针灸改善多囊卵巢综合征患者卵巢功能:随机对照预试验

发布时间：2018-01-12 12:31

本文关键词：董氏针灸改善多囊卵巢综合征患者卵巢功能:随机对照预试验　出处：《中国针灸》2017年07期 　论文类型：期刊论文

【摘要】：目的:初步评价董氏针灸改善多囊卵巢综合征(polycystic ovary syndrome,PCOS)患者卵巢功能的疗效。方法:将56例患者随机分为针刺组和药物组,针刺组穴取"妇科""还巢""天皇"(阴陵泉)、"人皇"(三阴交)、关元、子宫,一周2次,连续治疗12周;药物组口服达英-35片,1次/d,服药21 d,停药7 d,继续下一疗程,共治疗3个月经周期。以血清LH/FSH比值为主要指标,血清睾酮(T)、促卵泡刺激素(FSH)、促黄体生成素(LH)水平、体质量指数(BMI)、卵巢及月经情况为次要指标进行疗效评价。结果:(1)治疗后,针刺组和药物组血清LH/FSH比值均较治疗前下降(P0.05,P0.01),LH/FSH比值降低幅度两组间比较差异无统计学意义(P0.05)。(2)针刺组和药物组BMI及血清T、LH水平均较治疗前下降(P0.05,P0.01),但组间差值比较差异均无统计学意义(均P0.05)。(3)针刺组和药物组卵巢大小与治疗前比较差异均无统计学意义(均P0.05),针刺组卵巢大小的缩小幅度大于药物组(P0.05);针刺组卵巢单一切面卵泡数量10个的卵巢数量较治疗前减少(P0.05),减少程度两组间比较差异无统计学意义(P0.05)。(4)针刺组和药物组治疗后3个月内来潮次数及行经天数均较治疗前提高(均P0.01),但两组间差值比较差异均无统计学意义(均P0.05)。结论:董氏针灸能明显改善多囊卵巢综合征患者的卵巢功能,可达到与药物达英-35相当的疗效。
[Abstract]:Objective: to evaluate the effect of Dong's acupuncture on polycystic ovary syndrome. Methods: 56 patients were randomly divided into acupuncture group and drug group. Guan Yuan, uterus, 2 times a week, continuous treatment for 12 weeks; In the drug group, the drug group took diane-35 tablets once a day, 21 days, stopped for 7 days, followed by the next course of treatment, a total of three menstrual cycles, with the ratio of serum LH/FSH as the main index. Serum testosterone, follicle stimulating hormone (FSH), luteinizing hormone (LH), body mass index (BMI). Results the ratio of serum LH/FSH in acupuncture group and drug group was lower than that before treatment (P 0.05 P 0.01). There was no significant difference between the two groups in the reduction of LH/FSH ratio. The levels of BMI and serum LH in acupuncture group and drug group were lower than those before treatment (P 0.05. 0. 05, P 0. 05, P 0. 05, P 0. 05, P 0. 05, P 0. 05). There was no significant difference in ovarian size between acupuncture group and drug group (P 0.05). The reduction of ovarian size in acupuncture group was larger than that in drug group (P 0.05). In acupuncture group, the number of single cut follicles in 10 cases was lower than that before treatment (P 0.05). There was no significant difference in the degree of reduction between the two groups (P 0.05). The frequency of onset and the days of menstruation within 3 months after treatment in acupuncture group and drug group were higher than those before treatment (all P 0.01). But there was no significant difference between the two groups (P0.050.Conclusion: Dong's acupuncture and moxibustion can obviously improve the ovarian function of the patients with polycystic ovary syndrome, and can reach the same curative effect as the drug Dain-35.
【作者单位】：北京市中西医结合医院;中国中医科学院广安门医院针灸科;
【基金】：北京市中医药科技项目:JJ2015-42
【分类号】：R246.3
【正文快照】： 多囊卵巢综合征(polycystic ovary syndrome,PCOS)是一种以内分泌紊乱为主、多种代谢异常导致的常见病,是育龄期女性高发的一种临床综合征,发病率约为5.6%~10%,不孕女性中所占比例约为33%[1],以月经稀发或闭经、不孕、多毛和肥胖等为主要表现。PCOS导致的代谢紊乱不但严重影响

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