血管源性轻度认知障碍社区筛查情况及中医药干预研究

发布时间：2018-01-17 00:27

本文关键词：血管源性轻度认知障碍社区筛查情况及中医药干预研究　出处：《中华中医药杂志》2017年07期 　论文类型：期刊论文

【摘要】：目的:探讨血管源性轻度认知障碍(VMCI)社区筛查情况及中医药效果。方法:选择2015年1月-2016年12月石家庄市、廊坊市、沧州市10个社区年龄在50-80岁中筛查符合VMCI诊断且证型为"痰浊瘀阻,毒损脑络"的患者108例,随机分3组,比较3组患者的疗效及不同时点各项指标的变化。结果:对筛查中符合为"痰浊瘀阻,毒损脑络"的患者年龄进行分层(χ2=13.282)差异有统计学意义;对性别进行分层(χ2=0.915),差异无统计学意义。治疗后,3组患者不同时点MMSE、Mo CA、ADL评分和证候积分比较,差异具有统计学意义(P0.05)。3组患者不同时点主要症状(Z=2.893)和次要症状(Z=3.102)轻重程度经秩和检验比较,差异具有统计学意义(P0.05)。结论:应用化浊解毒活血通络法及中医特色治疗对VMCI进行早期干预,效果显著,且丰富了VMCI及预防血管性痴呆防治方法,值得临床推广应用。
[Abstract]:Objective: to investigate the community screening of VMCI and the effect of traditional Chinese medicine (TCM). Methods: Shijiazhuang City and Langfang City were selected from January 2015 to December 2016. In 10 communities of Cangzhou City, 108 patients, aged 50-80 years, who were diagnosed by VMCI and diagnosed as "phlegm turbid stasis, toxic damage to cerebral collateral", were randomly divided into 3 groups. To compare the curative effect of the three groups and the changes of various indexes at different time points. Results: the screening was consistent with "phlegm turbid stasis". The age of the patients with toxic damage to the Nao Luo "was significantly different (蠂 ~ 2: 13.282);" Sex was stratified (蠂 ~ 2 / 0.915), the difference was not statistically significant. After treatment, the scores of MMSE Mo / CAG ADL and syndromes were compared among the 3 groups at different time points. The difference was statistically significant (P 0.050.3.) the severity of the main symptoms at different time points was compared with that of the minor symptoms by rank sum test. The difference was statistically significant (P 0.05). Conclusion: the method of removing turbid, detoxifying, activating blood circulation and dredging collaterals and the characteristic treatment of traditional Chinese medicine are effective in the early intervention of VMCI. And enriched VMCI and prevention and treatment of vascular dementia, worthy of clinical application.
【作者单位】：河北省中医院;河北省唐县中医医院;河北沧州中西医结合医院;石家庄市中医院;廊坊市中医院;河北医科大学第二医院;河北省晋州市人民医院;
【基金】：河北省科技计划项目(No.15277748D) 河北省中医药管理局科研计划项目(No.2015016,No.2011029) 河北省省级中医药类重大医学科研课题项目(No.zyzd2013004)~~
【分类号】：R277.7
【正文快照】： 第二医院,石家庄050000;7河北省晋州市人民医院,石家庄052200)血管性认知障碍是由于各种血管病变引起的认知功能障碍,常表现为注意力减退、定向力障碍等[1],西医对其治疗仅局限在痴呆后的病情上,但效果不佳。因此早期识别、诊断和治疗轻度认知障碍(vascular mild cognitive im

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