基于因子分析与聚类分析的首发脑梗死急性期证候要素提取及证型研究

发布时间：2018-01-17 02:34

本文关键词：基于因子分析与聚类分析的首发脑梗死急性期证候要素提取及证型研究　出处：《中华中医药杂志》2017年05期 　论文类型：期刊论文

【摘要】：目的:探究首发缺血性脑梗死患者中医证候分布规律及特点。方法:运用SPSS 21.0进行因子分析和聚类分析。结果:本研究收集93个症状条目的KMO检验统计量为0.694,Bartlett的球形度检验近似卡方值为9 509.084(P0.05)。应用主成分分析方法得到21个公因子,对病性相同的证候要素进行合并后得到6个公因子为风、火、痰、瘀、气虚、阴虚,聚类分析得到5大类中医证候:第一类为肝肾阴虚和气滞血瘀合而为病,第二类为脾肾阳虚和风火上扰合而为病,第三类为痰热腑实和心脾两虚合而为病,第四类为痰火瘀闭证,第五类为痰浊瘀闭证。结论:因子分析和聚类分析结合可以通过首发脑梗死急性期症状间的复杂关系,定性、定量化地凝练该病中医证候要素,为进一步研究该病提供工作基础与必要条件。
[Abstract]:Objective: to investigate the distribution and characteristics of TCM syndromes in patients with first-episode ischemic cerebral infarction. Methods: factor analysis and cluster analysis were carried out with SPSS 21.0. Results:. The KMO test statistics of 93 symptom items collected in this study were 0.694. The approximate chi-square value of Bartlett's sphericity test was 9 509.084 (P0.05), and 21 common factors were obtained by principal component analysis (PCA). After merging the syndromes of the same disease, six common factors were obtained: wind, fire, phlegm, blood stasis, qi deficiency, yin deficiency, cluster analysis, and five kinds of TCM syndromes: the first type is the combination of Yin deficiency of liver and kidney and stagnation of qi and blood stasis. The second type is spleen and kidney yang deficiency and wind and fire on the disturbance for disease, the third type is phlegm heat and the deficiency of both heart and spleen for disease, 4th types for phlegm and fire stasis closed syndrome. Conclusion: the combination of factor analysis and cluster analysis can condense the TCM syndromes of the disease qualitatively and quantitatively through the complex relationship between the symptoms of acute phase of the first cerebral infarction. To provide the working basis and necessary conditions for further study of the disease.
【作者单位】：中国中医科学院中医临床基础医学研究所;中国中医科学院望京医院;
【基金】：国家中医药管理局中医药行业科研专项项目(No.201507003)~~
【分类号】：R277.7
【正文快照】： 脑梗死又称缺血性脑卒中[1],是指脑部血液供应障碍,脑组织缺血缺氧,导致局部脑组织发生软化坏死。其主要原因是由于脑血管出现动脉粥样硬化和血栓形成,使血管变得狭窄或者完全闭塞,导致血液供应障碍,具有高发病率、高致残率、高复发率、高病死率的特点。2013年通过分析《全国

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