内障病主方治疗湿性年龄相关性黄斑变性（脉络郁阻型）的疗效评价

发布时间：2018-01-17 21:03

  本文关键词：内障病主方治疗湿性年龄相关性黄斑变性（脉络郁阻型）的疗效评价　出处：《河南中医药大学》2016年硕士论文　论文类型：学位论文

  更多相关文章： WAMD 内障病主方 丹红化瘀口服液 脉络郁阻型

【摘要】：目的:本课题以中医理论为指导,在导师临床经验的指导下,通过对患者治疗过程中临床证候的观察及视力、FFA、OCT客观指标的测定,观察湿性年龄相关性黄斑变性(脉络郁阻型)患者用内障病主方治疗的综合疗效。为中医药治疗该病提供科学依据。方法:将确诊为WAMD脉络郁阻型的患者60例(79只眼),随机分为治疗组和对照组各30例;其中治疗组(40只眼)口服内障病主方,对照组(39只眼)口服丹红化瘀口服液。两组均按规定用药,详细观察治疗组与对照组治疗前后患者的视力、眼底、FFA、OCT及全身情况的变化。结果:(1)综合疗效方面:治疗组30例中总有效率93.3%,对照组中总有效率66.7%,(P=0.0330.05)有统计学意义,说明内障病主方治疗脉络郁阻型WAMD的综合疗效优于对照组。(2)中医证候方面:治疗组的30例中总有效率86.7%,对照组的30例中总有效率66.7%,(P0.05)有显著差异,表明治疗组疗效优于对照组。(3)视力方面:治疗后两组视力均有提升,治疗前两组视力比较的结果(P=0.0850.05),无统计学意义,有可比性。(4)眼底方面:治疗组有效率为92.5%,对照组有效率为71.8%,两组经比较(P=0.0200.05),表明治疗组好于对照组。(5)OCT方面:治疗组40只眼中总有效率87.5%。对照组39只眼中总有效率87.2%。(P=0.0310.05)有统计学意义。结论:(1)内障病主方能改善脉络郁阻型湿性年龄相关性黄斑变性患者的临床症状,提高视力,促进眼底玻璃膜疣、出血的吸收;(2)内障病主方具有开郁活血,通窍明目之功效,在治疗湿性年龄相关性黄斑变性脉络郁阻型时,能明显改善患者的体质,对疾病起到治疗及预防作用;(3)内障病主方对脉络郁阻型的湿性年龄相关性黄斑变性患者在治疗方面,其疗效明显优于国药准字的丹红化瘀口服液;(4)内障病主方服用安全有效,且易患者接受,有较好的社会经济效益。
[Abstract]:Objective: This study is based on Chinese medicine theory, in under the guidance of my tutor's clinical experience, through observation and vision, of course of treatment and clinical syndromes in patients with FFA, OCT determination of objective index to observe the wet age-related macular degeneration (choroid obstructing type) with cataract disease and comprehensive curative effect of treatment of patients. For traditional Chinese medicine to provide a scientific basis for treatment of the disease. Methods: the diagnosis of WAMD type of context Yu resistance in 60 patients (79 eyes), were randomly divided into treatment group and control group with 30 cases in each group; the treatment group (40 eyes) of cataract and oral disease, control group (39 eyes) with red blood oral liquid. Two groups were prescribed medication, with observation of treatment group and control group before and after treatment in patients with visual acuity, fundus changes, FFA, OCT and systemic conditions. Results: (1) the comprehensive curative effect: 30 cases in treatment group, the total efficiency of 93.3% in the control group, the total efficiency of 66.7% (P=0.0330.05). A system 璁″�︽剰涔�,璇存槑鍐呴殰鐥呬富鏂规不鐤楄剦缁滈儊闃诲瀷WAMD鐨勭患鍚堢枟鏁堜紭浜庡�圭収缁�.(2)涓�鍖昏瘉澹�

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