解肌退热方治疗外感发热临床疗效观察

发布时间：2018-01-17 21:26

本文关键词：解肌退热方治疗外感发热临床疗效观察　出处：《山东中医药大学》2016年硕士论文　论文类型：学位论文

【摘要】：目的:对比解肌退热方和清开灵颗粒治疗外感发热患者的临床疗效,并探讨其组方原理和作用机制。方法:根据外感发热的诊断标准和病例纳入标准,选取自愿参与研究的60例发热患者,按照随机分配的原则,分为观察组和对照组,每组30人,受试患者就诊前未服用退热药物,观察组给予协定方解肌退热方水煎服方案,对照组选用清开灵颗粒治疗,两组均为常规用量。治疗3天后,观察治疗前后两组患者的症状评分变化情况、服药后有效率,治疗前后外周血白细胞总数及中性粒细胞百分比、单核细胞百分比的变化情况,服药后退热时间,通过对比,判断解肌退热方的疗效。结果:通过比较两组患者服药后各项监测数据,在服药后退热时间、症状积分、白细胞总数、中性粒细胞百分比变化和有效率方面观察组优于对照组,(P0.05);单核细胞百分比变化两组无明显差别,(P0.05)。结论:解肌退热方能有效降低外感发热患者的体温,改善患者的临床症状、体征。
[Abstract]:Objective: to compare the clinical efficacy of Jieji antipyretic prescription and Qingkailing granule in the treatment of patients with external fever, and to explore the principle and mechanism of the prescription. Methods: according to the diagnostic criteria of external fever and the inclusion criteria of cases. Sixty patients with fever who volunteered to participate in the study were divided into observation group (n = 30) and control group (n = 30) according to the principle of random distribution. The patients did not take antipyretic drugs before going to hospital. The observation group was given the decoction of decoction of Shuijiefeng decoction, while the control group was treated with Qingkailing granule, the two groups were treated with routine dosage. After 3 days of treatment, the changes of symptom score before and after treatment were observed in the two groups. The effective rate, the percentage of neutrophils and neutrophils in peripheral blood before and after treatment, the change of percentage of monocyte, the time of antipyretic after taking medicine, were compared. Results: by comparing the monitoring data of two groups of patients after taking medicine, the time of antipyretic, symptom score and the total number of white blood cells after taking medicine were compared. The percentage change and effective rate of neutrophils in the observation group was better than that in the control group (P 0.05). There was no significant difference in the percentage of monocytes between the two groups. Conclusion: JJ antipyretic prescription can effectively reduce the body temperature of patients with external fever and improve the clinical symptoms and signs of the patients.
【学位授予单位】：山东中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R254

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