基于数据挖掘分析徐经世教授诊治肝郁脾虚型胃脘痛用药规律

发布时间：2018-01-22 20:33

本文关键词： 胃脘痛肝郁脾虚徐经世数据挖掘　出处：《中医杂志》2017年15期 　论文类型：期刊论文

【摘要】：目的分析国医大师徐经世教授诊治肝郁脾虚型胃脘痛的用药规律。方法收集徐经世教授诊治的肝郁脾虚型胃脘痛医案。运用结构化临床诊疗信息采集系统录入诊疗信息,通过数据挖掘技术分析诊治的常见症状、高频药物、核心药物组合等。结果本研究共搜集患者85例,157诊次,711个症状,药物103味。胃脘痛患者常见的临床症状有胃脘痛、嗳气、失眠,其中失眠的患者超过40%。出现频次超过50%的药物有竹茹、陈皮、绿萼梅、枳壳、半夏、黄连、酸枣仁。用药以甘平为主、归经以脾胃肝胆为主。复杂网络图显示竹茹、陈皮、绿萼梅、枳壳、半夏、黄连、酸枣仁、白芍为核心药物;中药药对关联规则显示竹茹→陈皮,绿萼梅→陈皮,陈皮→枳壳,绿萼梅→枳壳,绿萼梅→陈皮、竹茹,陈皮→绿萼梅、竹茹,竹茹→陈皮、绿萼梅等为药对。结论基于数据挖掘技术发现徐经世教授诊治肝郁脾虚型胃脘痛常用竹茹、陈皮、绿萼梅等药物用药以甘平为主,以肝胆脾胃为重。
[Abstract]:Objective to analyze the rule of medicine used by Professor Xu Jingshi, a master of Chinese medicine, in the diagnosis and treatment of epigastric pain due to liver depression and spleen deficiency. Methods to collect the medical records of stomachache of liver depression and spleen deficiency diagnosed by Professor Xu Jingshi, and to use structured clinical diagnosis and treatment information collection system to record the diagnosis. Therapeutic messages. Data mining technique was used to analyze the common symptoms, high frequency drugs, core drug combinations and so on. Results in this study, we collected 711 symptoms of 85 patients. The common clinical symptoms of patients with epigastric pain are epigastric pain, belching, insomnia, in which more than 40 patients with insomnia. The frequency of more than 50% drugs have bamboo Ru, Chen Pei, Green sepals, Fructus aurantii. Pinellia ternata, Rhizoma Coptidis, Zizyphus jujuba. The main drug is Ganping, and the main medicine is the spleen, stomach, liver and gallbladder. Chinese herbal medicine pair association rules show Zhu Ru. 鈫扜reen sepals. 鈫扖hen Pei. 鈫扚ructus aurantii. 鈫扚ructus aurantii. 鈫扖hen Pei. 鈫扜reen sepals. 鈫扖onclusion based on the data mining technology, Professor Xu Jingshi used to treat stomachache of liver stagnation and spleen deficiency type, such as ZhuRu, Chen Pei, Green sepals Plum, etc. Gan Ping was the main drug, and liver, gallbladder, spleen and stomach were the most important drugs.
【作者单位】：安徽中医药大学第一附属医院;安徽中医药大学第三附属医院;
【基金】：国家中医药管理局徐经世国医大师传承工作室国家自然科学基金(81603574) 安徽省自然科学基金(1708085QH213) 安徽省卫计委中医药科研课题(2016zy20) 安徽中医药大学校级科学研究基金(2016fy037)
【分类号】：R249;R256.33
【正文快照】： 胃脘痛的基本治则为理气和胃止痛,常用治法有温胃散寒、疏肝解郁、行气止痛、消食和胃、清中化湿、活血化瘀、养阴益胃等[1]。徐经世教授系第二届国医大师,尤擅长诊治脾胃肝胆系统疾病,对于胃脘痛的辨治提出温中健脾、缓急止痛法,燥湿散寒、行气止痛法,疏肝理气、通降止痛法,

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