通络生乳方治疗剖宫产后缺乳临床效果观察
发布时间:2018-01-27 16:45
本文关键词: 通络生乳方 缺乳 剖宫产 泌乳素 乳房胀度 泌乳量 出处:《中药药理与临床》2017年02期 论文类型:期刊论文
【摘要】:目的:评价通络生乳方治疗剖宫产术后产妇缺乳的临床疗效及其安全性。方法:将202例剖宫产术后缺乳产妇随机分为治疗组(n=102),口服给予通络生乳方连续7天,每日3次,每次50 ml(每次相当于50 g生药);对照组(n=100)不服用任何催乳药物。治疗前后进行常规体检,观察乳房胀度,测量血清泌乳素、泌乳量和乳汁中蛋白质含量,评价疗效。结果:观察期间未见到明显不良反应。两组产妇在治疗前的血清泌乳素、乳房胀度和泌乳量比较差异均无统计学意义。治疗组产妇服用通络生乳方7天后,血清泌乳素水平达到(369.2±87.7)μg/L,乳房胀度显著增加,总积分均值达(7.6±2.6),泌乳量平均增加了(24.0±14.7)ml,与自身试验前及对照组比较,差异均有统计学意义。治疗7天后,总有效率治疗组达90.2%,与对照组的44.0%比较,差异有统计学意义,而两组产妇乳汁中蛋白质含量未见明显差别。结论:通络生乳方对剖宫产术后缺乳产妇安全有效。
[Abstract]:Objective: to evaluate the clinical efficacy and safety of Tongluo Shengru recipe (Tongluo Shengru recipe) in the treatment of lack of milk after cesarean section. Methods: 202 cases of women with lack of milk after cesarean section were randomly divided into treatment group (n = 102). Tongluo Shengru recipe was given orally for 7 consecutive days, 3 times a day, each time 50 ml (equal to 50 g crude medicine each time); The control group did not take any prolactin. Routine physical examination was performed before and after treatment. Breast distension was observed, serum prolactin, lactation volume and protein content in milk were measured. Results: no obvious adverse reactions were observed during the observation period. The serum prolactin levels of the two groups were measured before treatment. There was no significant difference in breast distention and lactation volume. In the treatment group, the serum prolactin level reached 369.2 卤87.7 渭 g / L after taking Tongluo Shengru recipe for 7 days. The breast distention increased significantly, the mean value of total integral was 7.6 卤2.6g, and the average lactation volume increased 24.0 卤14.7 ml, which was compared with that before the self-test and the control group. After 7 days of treatment, the total effective rate in the treatment group reached 90.2%, which was significantly higher than that in the control group (44.0%). Conclusion: Tongluo Shengru recipe is safe and effective for breast-deficient women after cesarean section.
【作者单位】: 湖南省疾病预防控制中心;湖南省妇幼保健院;湖南师范大学医学院;
【基金】:湖南省中医药科研计划项目(201407)
【分类号】:R271.4
【正文快照】: 3湖南师范大学医学院,长沙410013)产后缺乳是产妇在哺乳时乳腺泌乳量甚少或全无,不能满足婴儿喂养需要。该病多发生在产后的2~3天至半月内,发病率约为产妇的20%~30%[1]。近年来,随着二孩政策的全面放开,产妇年龄趋高,剖宫产率相对上升以及妊娠期精神过度紧张、产后疲劳、乳腺
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