隔姜灸脐法联合中药对宫寒性不孕症患者子宫内膜容受性的影响

发布时间：2018-01-29 16:58

本文关键词： 宫寒不孕症子宫内膜容受性隔姜灸脐法　出处：《湖北中医药大学》2017年硕士论文　论文类型：学位论文

【摘要】：目的观察隔姜灸脐法对宫寒性不孕症患者子宫内膜容受性的改善作用,进一步了解中医外治法在治疗不孕症方面的优势,为临床治疗宫寒性不孕症提供新的思路和方法,从而提高妊娠率和妊娠成功率。方法按照研究标准将确诊为宫寒不孕症的患者100例,随机分为治疗组和对照组各50例。治疗组给予外治法隔姜灸脐法和内服补肾活血、调经暖宫的中药(白芍、吴茱萸、桂枝、小茴、法夏、党参、当归、丹皮、三棱、川芎、丹参、莪术、菟丝子、五味子)治疗,隔姜灸脐法每隔十日一次,中药一日一剂,水煎服,早晚各1次;对照组仅给予补肾活血、调经暖宫中药口服治疗,一日一剂,水煎服,早晚各一次。1个月为1个疗程,治疗3个疗程。以三维彩色多普勒超声诊断仪作为监测手段,检测两组患者治疗前后子宫内膜厚度(Em)、子宫内膜类型、子宫内膜容积、子宫动脉血流(搏动指数PI、阻力指数RI)、子宫螺旋动脉血流(PI、RI)、子宫内膜血流情况,并观察患者治疗前后临床症状和体征改善、妊娠情况,三个月后将监测所得数据运用SPSS 19.0统计分析软件进行统计学处理。结果(1)两组患者卵泡期和排卵期的子宫内膜厚度、内膜形态、内膜容积、子宫动脉和螺旋动脉PI、RI以及子宫内膜血流指标经治疗后均得到了不同程度的改善;与对照组比较,治疗组疗效更好,差异具有统计学意义(P0.05);(2)两组患者的临床症状和体征经治疗后均获得改善,治疗组的总有效率高达94%,与对照组比较,疗效更为显著,差异具有统计学意义(P0.05);(3)两组患者的妊娠率及妊娠成功率统计结果显示,治疗组的妊娠率为74%,妊娠成功率为32%,均高于对照组,尤其是妊娠率差异显著,具有统计学意义(P0.05)。结论隔姜灸脐法能够有效改善宫寒性不孕症的子宫内膜容受性,减轻患者的临床症状和体征,提高妊娠率及妊娠成功率。中药联合隔姜灸脐法治疗宫寒不孕症,体现了中医内外兼治的思想,且疗效优于单纯的中药内服,在不孕症的治疗方面占有很大的优势,此方法值得我们推广。
[Abstract]:Objective to observe the effect of ginger-separated moxibustion on endometrial receptivity in patients with uterine cold infertility, and to further understand the advantages of external treatment of traditional Chinese medicine in the treatment of infertility. To provide new ideas and methods for clinical treatment of uterine cold infertility, so as to improve the pregnancy rate and pregnancy success rate. Methods 100 cases of uterine cold infertility were diagnosed according to the research standard. The treatment group was randomly divided into treatment group (n = 50) and control group (n = 50). The treatment group was treated with external treatment of ginger separated moxibustion and umbilical moxibustion, internal administration of tonifying kidney and activating blood circulation, regulating meridian and warming palace Chinese medicine (Radix Paeoniae Alba, Evodia Fructus Corni, Guizhi, small anise, Faxia, Codonopsis, Radix. Sanleng, Chuanxiong, Salvia miltiorrhiza, Curcuma, Cuscuta, Schisandra) treatment, ginger-separated moxibustion umbilical method every 10th, Chinese medicine 1st a dose, water decoction, morning and evening, 1; The control group was only given tonifying kidney and activating blood circulation, regulating meridian and warming palace Chinese medicine oral treatment, 1st, one dose, water decoction, once in the morning and evening. 1 month as a course of treatment. Three courses of treatment. Using 3D color Doppler ultrasound as a monitoring method, the endometrial thickness, endometrial type and endometrial volume were measured before and after treatment in two groups. Uterine artery blood flow (pulsatile index Pi, resistance index RIN), uterine spiral artery blood flow (Pi), endometrial blood flow, and observe the improvement of clinical symptoms and signs before and after treatment. Pregnancy data were analyzed by SPSS 19.0 statistical analysis software after 3 months. Results the endometrial thickness and endometrial morphology in follicular phase and ovulation stage were analyzed in both groups. Endometrial volume, PIRI of uterine artery and spiral artery and endometrial blood flow index were improved to some extent after treatment. Compared with the control group, the curative effect of the treatment group was better, the difference was statistically significant (P 0.05). 2) the clinical symptoms and signs of the two groups were improved after treatment, the total effective rate of the treatment group was as high as 94%, compared with the control group, the curative effect was more significant, the difference was statistically significant (P 0.05); The statistical results of pregnancy rate and pregnancy success rate of the two groups showed that the pregnancy rate of the treatment group was 74 and the success rate of pregnancy was 322.It was higher than that of the control group, especially the difference of pregnancy rate was significant. Conclusion Ginger-separated moxibustion with umbilical method can effectively improve the endometrial receptivity of uterine cold infertility and alleviate the clinical symptoms and signs of the patients. Improve the pregnancy rate and pregnancy success rate. Traditional Chinese medicine combined with ginger-separated moxibustion umbilical method for the treatment of uterine cold infertility, reflects the thinking of internal and external treatment of Chinese medicine, and the curative effect is better than the simple Chinese medicine. In the treatment of infertility has a great advantage, this method is worthy of our promotion.
【学位授予单位】：湖北中医药大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R271.14

【参考文献】