益气养阴行气润肠法治疗老年人功能性便秘的临床疗效评价

发布时间：2018-02-08 13:01

本文关键词： 益气养阴行气润肠法中药颗粒剂老年人功能性便秘临床疗效评价　出处：《河北医科大学》2017年硕士论文　论文类型：学位论文

【摘要】：目的:在中医理论的指导下,运用益气养阴行气润肠法治疗老年人功能性便秘,科学系统地对受试者疗效进行评分、记录、数据分析,对此方法的临床疗效进行评价。方法:本研究采取随机、对照的方法,将2015年9月至2016年11月间,河北省中医院肛肠二科门诊就诊的老年功能性便秘患者中属于中医诊断为气阴亏虚证型的病历,共60例,分为治疗组和对照组,每组30例。治疗组予益气养阴行气润肠功效的中药颗粒剂口服,对照组予麻仁软胶囊口服,两组均以10天为1疗程,共治疗和观察记录3个疗程,将两组患者治疗前后的临床症状,按评分标准打分。治疗结束4周后对两组患者进行随访,按评分标准打分。对两组最终收集的数据,使用SPSS19.0统计软件进行统计学分析,从多角度评价本方法的临床疗效。治疗期间,嘱全部患者停止使用影响肠动力的药物,合理膳食,规律作息,积极配合。结果:共完成临床观察病例52例,包括治疗组27例,对照组25例。1治疗组与对照组综合疗效比较,总有效率治疗组为85.2%,对照组为72.0%,两组总有效率比较P0.05,无统计学意义,说明两组治疗方法均有效;总显效率治疗组33.3%,对照组8.0%,P0.05,说明有统计学意义,治疗组疗效优于对照组;2性别与疗效的相关性比较,男性患者两种治疗的疗效无差异,女性患者两种治疗的疗效无差异。治疗组男性与女性患者疗效无差异,对照组男性与女性患者疗效无差异;3病程与疗效的相关性比较,病程在5年内及10年以上的患者中治疗组疗效优于对照组;4两组受试者3个疗程治疗结束,4周后随访,治疗组复发率为17.4%,对照组复发率为50%,两组复发率经卡方检验:χ2=4.96,P=0.03,P0.05,有统计学差异,说明远期疗效治疗组优于对照组。结论:益气养阴行气润肠法对老年人功能性便秘的疗效确切,在综合疗效、较长病程的老年人功能性便秘的治疗方面效果显著,且复发率低,无明显副作用,值得推广。
[Abstract]:Objective: under the guidance of traditional Chinese medicine theory, the treatment of functional constipation in the elderly with the method of nourishing qi and nourishing yin and nourishing qi and nourishing intestines was used to scientifically and systematically evaluate, record and analyze the curative effect of the subjects. Methods: a randomized, controlled method was used to evaluate the clinical efficacy of this method from September 2015 to November 2016. Among the elderly patients with functional constipation diagnosed as deficiency of qi and yin, 60 cases were divided into treatment group and control group. 30 cases in each group. The treatment group was treated with traditional Chinese medicine granules of invigorating qi, nourishing yin and nourishing qi and nourishing intestines. The control group was given Maren soft capsule orally. The two groups were treated with 10 days as a course of treatment, and three courses of treatment were observed and recorded. The clinical symptoms of the two groups before and after treatment were scored according to the scoring standard. The patients in the two groups were followed up 4 weeks after the treatment and scored according to the scoring standard. The final data collected in the two groups were statistically analyzed by SPSS19.0 statistical software. The clinical effect of this method was evaluated from various angles. During the treatment, all patients were told to stop using drugs affecting intestinal motility, reasonable diet, regular rest and active cooperation. Results: a total of 52 cases of clinical observation were completed, including 27 cases in the treatment group. The total effective rate was 85.2in the treatment group and 72.0 in the control group. There was no statistical significance in the total effective rate between the two groups (P 0.05), which indicated that the two treatment methods were effective. The total effective rate of treatment group was 33. 3 and that of control group was 8. 0% P 0. 05, which indicated that there was statistical significance. The curative effect of treatment group was better than that of control group. There was no difference in curative effect between male and female patients in treatment group, and there was no difference between male and female patients in control group. The curative effect of the treatment group was better than that of the control group in the course of 5 years or more than 10 years. The patients in the two groups were followed up for 4 weeks after 3 courses of treatment. The recurrence rate of the treatment group was 17.4 and that of the control group was 50. The recurrence rate of the two groups was tested by chi-square test. There was statistical difference between the two groups, indicating that the long-term curative effect of the treatment group was better than that of the control group. Conclusion: the therapy of nourishing qi, nourishing yin and nourishing qi and nourishing the intestines is effective in treating functional constipation in the elderly. In the treatment of functional constipation in the elderly with long course of disease, the curative effect is significant, and the recurrence rate is low, no obvious side effects, so it is worth popularizing.
【学位授予单位】：河北医科大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R256.35

【参考文献】