原发性高血压中医证素分布及其与影响因素的相关性研究

发布时间：2018-02-09 03:39

本文关键词： 原发性高血压中医证素影响因素　出处：《中华中医药杂志》2017年12期 　论文类型：期刊论文

【摘要】：目的:分析原发性高血压患者(EH)的中医证素分布及其与影响因素的相关性。方法:采用临床横断面研究方法,收集EH患者的四诊信息及影响因素指标。运用逻辑回归分析等统计学方法进行相关性分析。结果:共纳入病例1 192例,涉及主要证素12种:肾、肝、心、脾;湿、阳亢、痰、火(热);气虚、阴虚、精亏、血虚。双因素组合出现较多的证素为肝+肾、痰+湿和气虚+阴虚;三因素组合证素出现较多的为肝+肾+心、阳亢+痰+湿和精亏+气虚+阴虚。60岁以下的女性患者与肾最相关,男性则为精亏;61-70岁的女性与心最相关,男性则为火(热);80岁以上的女性与火(热)最相关,男性则为痰。湿证与体质量指数(BMI)值正相关,阴虚则相反。阴虚和阳亢与血压等级正相关。肾、精亏和阳亢与高血压病史正相关。结论:原发性高血压中医证素的分布与患者的性别、年龄、体质量指数、高血压等级及高血压病史均具有统计学相关性。
[Abstract]:Objective: to analyze the distribution of TCM syndromes and its correlation with influencing factors in patients with essential hypertension. The information of four diagnoses of EH patients and their influencing factors were collected. The correlation analysis was carried out by means of logistic regression analysis and other statistical methods. Results: 1 192 cases were included in this study, which involved 12 main syndromes: kidney, liver, heart, spleen, dampness, hyperactivity of yang, phlegm, phlegm, kidney, liver, heart and spleen. Fire (heat); Qi deficiency, yin deficiency, essence deficiency, blood deficiency. More syndromes appeared in the combination of two factors: liver and kidney, phlegm and dampness and deficiency of qi yin, and three factors combination syndrome factors were liver, kidney and heart, Phlegm dampness and deficiency of qi and deficiency of qi. Female patients under 60 years of age had the most correlation with kidney, male patients with 61-70 years of age had the most correlation with heart, and male patients with fire (female over 80 years of age) were most related to fire (heat). In men, phlegm, dampness syndrome and body mass index (BMI) were positively correlated, while Yin deficiency and hyperactivity of yang were positively correlated with blood pressure grade. Conclusion: the distribution of TCM syndromes in essential hypertension is positively correlated with sex, age, body mass index, grade of hypertension and history of hypertension.
【作者单位】：上海中医药大学;上海市浦东新区王港社区卫生服务中心;
【基金】：上海市卫生系统优秀学科带头人培养计划(No.XBR2011070) 国家自然科学基金项目(No.30873398) 上海市博士点建设基金项目(No.K110412)~~
【分类号】：R259

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