寻常型银屑病中医辨证和药物共现分析研究

发布时间：2018-02-14 18:29

本文关键词： 寻常型银屑病中医证治用药规律共现分析　出处：《辽宁中医药大学》2017年硕士论文　论文类型：学位论文

【摘要】：目的:通过整理中医药治疗寻常型银屑病的相关文献,总结医案中的信息,探索中医药治疗寻常型银屑病的相关规律。方法:统计中医治疗寻常型银屑病在中国知网、维普数据库等2003-2017年间国内权威数据库及省级以上的中医药期刊文献及各中医院校2003-2016年硕士毕业生论文,共收集资料94篇,涉及中药201种。利用Microsoft Excel、SPSS17.0软件及Net Draw社会网络分析软件建立资料数据表,分析中医证治及用药规律,对中医治疗寻常型银屑病进行基本总结。结果:中医辨证分型出现频次主要为血热型、血瘀型、血燥型、血虚风燥型,分别为45、43、38、22次;脏腑辨证分型出现频次主要为肝肾阴虚型、风热犯肺型、脾虚湿盛型,分别为5、3、3次。舌色分布出现频次主要为红舌、暗舌、淡红舌,分别为66、34、29次;舌苔分布出现频次主要为黄苔、薄苔、腻苔,分别为63、53、42次;脉象分布出现频次主要为数脉、细脉、滑脉、弦脉,分别为59、42、39、31次。单味用药使用频次在50次以上的药物有10种,包括生地黄、赤芍、当归、甘草、丹参、紫草、土茯苓、牡丹皮、白鲜皮、金银花;药物分类使用主要为清热药、补虚药、活血化瘀药;进展期用药中主要以清热药为主;静止期主要以活血化瘀药为主;消退期主要以补益药为主。结论:1.寻常型银屑病的中医辨证分型主要是血热型、血瘀型、血燥型;脏腑辨证分型主要是肝肾阴虚型、风热犯肺型、脾虚湿盛型;2.寻常型银屑病治疗药物使用频次最多的主要是清热药、补虚药、活血化瘀药,单味用药使用频次前10位(由高到低)依次为生地黄、赤芍、当归、甘草、丹参、紫草、土茯苓、牡丹皮、白鲜皮、金银花;3.寻常型银屑病进展期药物使用频次最主要的是清热药活血化瘀药,与治疗效果密切相关的药物为生地黄、赤芍、牡丹皮。4.寻常型银屑病静止期药物使用频次最主要的是活血化瘀药补益药清热药,以活血化瘀药为主,与治疗效果密切相关的药物为当归、生地黄、鸡血藤。5.寻常型银屑病消退期药物使用频次最主要的是补益药活血化瘀清热药,以补益药为主,与治疗效果密切相关的药物为当归、丹参、赤芍、白花蛇舌草。
[Abstract]:Objective: to summarize the information in medical records of traditional Chinese medicine in the treatment of psoriasis vulgaris, and to explore the relevant rules of traditional Chinese medicine in the treatment of psoriasis vulgaris. Methods: statistics of TCM treatment of psoriasis vulgaris in China, From 2003 to 2017, the database of Weip and other authoritative databases, the literature of Chinese medicine periodicals above the provincial level and the graduate papers of Chinese medicine colleges and universities in 2003-2016 were collected, and 94 articles were collected. Using Microsoft Excel SPSS 17.0 software and Net Draw social network analysis software to establish data table, to analyze the law of TCM syndrome and treatment and drug use. Results: the main types of TCM syndrome differentiation were blood heat type, blood stasis type, blood dryness type, blood deficiency type and wind dryness type, respectively. The frequency of tongue color distribution was mainly red tongue, dark tongue and light red tongue, respectively, and the distribution frequency of tongue coating was mainly yellow fur, thin fur and greasy coating, respectively, and the frequency of tongue color distribution was red tongue, dark tongue and light red tongue, respectively, and the distribution frequency of tongue coating was mainly yellow fur, thin fur and greasy coating, respectively. The frequency of pulse distribution was mainly composed of several veins, thin veins, smooth veins and chord veins, respectively, with a frequency of 59 ~ 42 and 39 ~ 31 times respectively. There were 10 kinds of drugs which were used more than 50 times, including Rehmannia, Radix Paeoniae Paeoniae, Radix angelicae Sinensis, Radix Glycyrrhizae, Salvia miltiorrhiza, Radix Purple Rhizoma, Poria cocos, and Radix Paeoniae Sinensis. Peony peel, white fresh skin, honeysuckle; classified medicine is mainly used as heat-clearing medicine, tonifying medicine, promoting blood circulation and removing blood stasis medicine; Conclusion 1. The syndrome differentiation of psoriasis vulgaris is mainly divided into blood heat type, blood stasis type, blood dryness type, liver and kidney yin deficiency type, wind heat invading lung type. The most frequently used drugs for psoriasis vulgaris are heat-clearing medicine, tonifying medicine, promoting blood circulation medicine and removing blood stasis medicine. The top 10 (from high to low) of single drug use frequency are Rehmannia, Radix Paeoniae Alba, Angelica sinensis, Radix Glycyrrhizae, Salvia miltiorrhiza, Salvia miltiorrhiza and Radix Salviae Miltiorrhizae. Purple grass, Poria cocos, peony peel, white fresh skin, honeysuckle 3. The most important drug used in the advanced stage of psoriasis vulgaris is the antipyretic drug for promoting blood circulation and removing blood stasis, and the drugs closely related to the therapeutic effect are Rehmannia, Radix Paeoniae rubra and Radix Paeoniae rubra. Peony skin .4.The most frequent use of drugs in stationary stage of psoriasis vulgaris is activating blood circulation and removing blood stasis and tonifying heat drugs, mainly promoting blood circulation and removing blood stasis. The drugs closely related to the therapeutic effect are angelica sinensis, Rehmannia and Rehmannia. The main drugs used in the extinction period of psoriasis vulgaris were tonifying medicine, activating blood circulation and removing blood stasis and clearing heat, mainly with tonifying drugs, and the drugs closely related to the therapeutic effect were Angelica, Salvia miltiorrhiza, Radix Paeoniae Alba, and Herba Phellodendri.
【学位授予单位】：辽宁中医药大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R275.9

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