育阴止崩汤治疗阴虚血热型月经过多的临床观察

发布时间：2018-02-16 04:47

本文关键词： 月经过多育阴止崩汤阴虚血热型　出处：《福建中医药大学》2016年硕士论文　论文类型：学位论文

【摘要】：目的：本课题探讨育阴止崩汤对阴虚血热型月经过多患者的影响,并与西药氨甲环酸片对照,观察治疗后患者月经失血量、血红蛋白含量、月经过多特异性生存质量(包括经期活动受限、经期疲倦、经期烦躁、经期情绪低落程度受累评分及时间受累评分)、子宫内膜厚度、远期调经疗效以及中医症状改善的情况。对育阴止崩汤治疗阴虚血热型月经过多临床疗效进行客观的评价,为月经过多中医辨证专方的研究提供客观依据。方法：选取福建中医药大学附属人民医院妇科门诊患者60例,按随机数字表法分为治疗组30例和对照组30例,治疗组予中药育阴止崩汤,对照组予氨甲环酸,观察比较育阴止崩汤和氨甲环酸在治疗前与治疗后对月经失血量评分、血红蛋白含量、生存质量、子宫内膜厚度、远期调经疗效以及中医症状情况。通过对比,以期对育阴止崩汤治疗阴虚血热型月经过多临床疗效进行客观的评价。结果：1.治疗组总有效率86.67%；对照组总有效率83.33%。两组患者综合疗效比较,差异无统计学意义(P0.05),表明两组综合疗效相当。2.两组治疗后与各自治疗前症状总积分比较,均有显著性差异(P0.05)；两组患者治疗后组间症状总积分比较,差异有统计学意义(P0.05)；治疗后两组患者中医证候疗效比较,差异有统计学意义(P0.05),提示治疗组在改善中医症状方面优于对照组。3.两组治疗后与各自治疗前月经失血量比较,均有显著差异(P0.05)；治疗后两组组间月经失血量比较无显著差异(P0.05),说明两组改善月经失血量方面效果相当。4.两组治疗后月经过多特异性生存质量评分(包括经期活动受限、经期疲倦、经期烦躁、经期情绪低落程度受累评分及时间受累评分)与各自治疗前比较,均有显著性差异(P0.05)；治疗后两组组间比较差异无统计学意义(P0.05),表明育阴止崩汤在改善月经过多特异性生存质量方面与对照组相当。5.两组治疗后血红蛋白含量与各自治疗前对比,均有显著差异(P0.05)；治疗后两组组间比较,差异有统计学意义(P0.05),表明治疗组在改善血红蛋白含量方面优于对照组。6.治疗组治疗前后子宫内膜厚度有显著性差异(P0.05),对照组治疗前后无显著性差异(P0.05),治疗后治疗组及对照组子宫内膜厚度比较有显著差异(P0.05)。说明治疗组改善子宫内膜厚度。7.两组比较随访3个月经周期的调经疗效,差异有统计学意义(P0.05),表明育阴止崩汤在随访3个月经周期的调经疗效方面优于对照组。结论：运用育阴止崩汤治疗阴虚血热型月经过多,能明显改善中医症状,减少月经失血量.改善月经过多特异性生存质量,提高血红蛋白含量,有效改善子宫内膜厚度,能巩固调整月经疗效。且无明显不良反应,显示了中医辨证治疗本病的优越性,为阴虚血热型月经过多中医辨证专方的研究提供客观依据。
[Abstract]:Objective: to investigate the effect of Yuyin Zhibong decoction on menorrhagia of yin deficiency and blood heat type, and to observe the amount of menorrhagia and the content of hemoglobin in patients with menorrhagia after treatment. Menstrual specific quality of life (including menstrual activity restriction, menstrual fatigue, menstrual irritability, menstrual depression and time involvement score, endometrial thickness, The long-term effect of regulating menstruation and the improvement of TCM symptoms. Objective evaluation was made on the clinical efficacy of Yuyin Zhibong decoction in treating menorrhagia of Yin-deficiency and blood-heat type. Methods: 60 gynecological outpatients of people's Hospital affiliated to Fujian University of traditional Chinese Medicine were selected and randomly divided into treatment group (30 cases) and control group (30 cases). The treatment group was treated with Yuyin Zhibong decoction, while the control group was treated with carbamate. The blood loss score, hemoglobin content, quality of life and endometrial thickness before and after treatment were observed and compared between the treatment group and the control group. Long-term effects of menstrual regulation and symptoms of traditional Chinese medicine. Through comparison, Results: 1. The total effective rate of the treatment group was 86.677.The total effective rate of the control group was 83.33.The comprehensive curative effect of the two groups was compared. There was no significant difference between the two groups (P 0.05), which indicated that the comprehensive curative effect of the two groups was equivalent. 2. There was significant difference in the total score of symptoms between the two groups after treatment and before treatment, and there was a significant difference in the total score of symptoms between the two groups after treatment, and there was a significant difference between the two groups in the total score of symptoms after treatment. The difference was statistically significant (P 0.05), and the difference between the two groups after treatment was statistically significant (P 0.05), suggesting that the treatment group was superior to the control group in improving the symptoms of traditional Chinese medicine. The amount of menstrual blood loss in the two groups after treatment was higher than that in the control group before and after treatment. There was no significant difference in menstrual blood loss between the two groups after treatment, which indicated that the two groups had the same effect in improving menstrual blood loss. 4. The specific quality of life score (including limited menstrual activity) in the two groups after treatment. Menstrual fatigue, menstrual irritability, menstrual depression degree of involvement score and time involvement score) compared with their pre-treatment, There was no significant difference between the two groups after treatment (P 0.05), which indicated that Yuyin Zhibong decoction was comparable to the control group in improving the quality of life of menstrual hypertrophy. The hemoglobin content of the two groups was compared with that of the control group before and after treatment. There were significant differences between the two groups after treatment. The difference was statistically significant (P 0.05), which indicated that the treatment group was superior to the control group in improving hemoglobin content. 6. There was a significant difference in endometrial thickness before and after treatment in the treatment group, but there was no significant difference in the endometrial thickness in the control group before and after treatment (P 0.05). There was a significant difference in endometrial thickness between the two groups (P 0.05), which indicated that the treatment group improved endometrial thickness. 7. The two groups were followed up for 3 menstrual cycles. The difference was statistically significant (P 0.05), which indicated that Yuyin Zhibong decoction was superior to the control group in regulating menstruation in three menstrual cycles. Conclusion: Yuyin Zhibong decoction can obviously improve the symptoms of traditional Chinese medicine in treating menorrhagia of yin deficiency and blood heat type. Reduce the amount of menstrual bleeding, improve the specific quality of life of menstruation, increase the content of hemoglobin, effectively improve the thickness of endometrium, can consolidate and adjust menstrual efficacy, and there is no obvious adverse reactions, showing the advantages of TCM syndrome differentiation treatment of this disease, To provide an objective basis for the study of TCM syndrome differentiation prescription for menstruation with yin deficiency and blood heat.
【学位授予单位】：福建中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R271.111

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