基于中医络病理论治疗特发性肺纤维化临床疗效的Meta分析

发布时间：2018-02-21 09:19

本文关键词： 特发性肺纤维化络病理论 Meta分析　出处：《中华中医药杂志》2017年07期 　论文类型：期刊论文

【摘要】：目的:运用Meta分析方法对基于中医络病理论组方或中药治疗特发性肺间质纤维化(IPF)的临床疗效进行评估。方法:计算机检索CNKI、CBM、万方三大数据库,以及百度学术、谷歌学术两大搜索引擎,筛选符合纳入及排除标准的文献,使用Rev Man 5.0软件进行统计学分析。结果:共纳入文献11篇,共计594例患者。荟萃分析结果:通络中药试验组总有效率明显高于西药对照组;且在改善喘息、咳嗽、气短、胸闷、VelcroUp音、PaO2、肺部再感染情况、生活质量心理状况维度、6min步行试验、不良反应发生率方面较西药组疗效更优。漏斗图提示本结果具有可信性。结论:基于中医络病理论治疗IPF具有良好疗效,该思路为未来中医辨治IPF提供重要方向。
[Abstract]:Objective: to evaluate the clinical efficacy of traditional Chinese medicine (TCM) or traditional Chinese medicine (TCM) in treating idiopathic pulmonary interstitial fibrosis (IPF) with Meta analysis method. Rev Man 5.0 software was used to analyze the two major academic search engines of Google. Results: 11 articles were included. A total of 594 patients. Meta-analysis results: the total effective rate of Tongluo TCM trial group was significantly higher than that of western medicine control group, and in improving wheezing, coughing, shortness of breath, chest tightness with VelcroUp Pao _ 2, pulmonary re-infection, quality of life psychological status dimension 6 minutes walking test. The incidence rate of adverse reactions was better than that of western medicine group. Funnel graph showed that this result had credibility. Conclusion: the treatment of IPF based on TCM collateral disease theory has a good effect, which provides an important direction for TCM differentiation and treatment of IPF in the future.
【作者单位】：辽宁中医药大学;辽宁中医药大学附属医院;
【基金】：国家自然科学基金面上项目(No.81373579);国家自然科学基金青年基金项目(No.81403290) “十二五”国家中医药管理局中医络病重点学科建设项目辽宁省科技厅计划项目(No.2012225018-202) 辽宁省中医临床重点学(专)科服务能力建设项目(No.2013-LNZYXZK-2) 辽宁省高等学校科学研究一般项目科学基础研究(No.L2014369) 沈阳市科技局计划项目(No.F14-231-1-13)~~
【分类号】：R259

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