胃息肉证素分布特点的研究

发布时间：2018-03-03 15:07

本文选题：胃息　切入点：中医证素　出处：《南京中医药大学》2016年硕士论文　论文类型：学位论文

【摘要】：目的：通过对胃息肉患者临床调查,分析归纳其证素分布规律及相关因素,完善胃息肉的临床诊疗辨证体系,为临床治疗及预防提供依据。方法：收集符合诊断标准的胃息肉患者257例,详细记录四诊信息及年龄、性别等基本信息。参考朱文峰主编的《证素辨证学》中的“证候辨证量表”提取相关证素,建立数据库,运用SPSS17.0软件统计分析,归纳胃息肉的证素分布规律及相关因素。结果：1.共收集胃息肉患者257例,男性100例,女性157例,男女比例1：1.57,最小年龄14岁,最大年龄85岁。2.胃息肉单发者77.04%,多发者22.96%,比值为：3.36：1。息肉生长以单部位为主,占89%,其次是双部位(10%),三个部位(1%)。胃体109例(42.41%),胃窦81例(31.52%),贲门47例(18.29%),胃底41例(15.95%),胃角9例(3.5%)。男女间的各部位分布有统计学差异(P=0.000)。男性以胃体和胃窦为主,女性以胃体为主。Hp阳性者占12.84%。病理结果示炎性息肉最多(65.76%),其次为胃底腺息肉(22.96%)、增生性息肉(11.67%)、腺瘤性息肉(2.33%)。3.257例胃息肉患者可提取出证素者204例。排除频数分布比例2%的证素,发现主要的病位证素有胃(90.20%)、脾(60.78%)、肝(19.61%)、胆(2.94%)。证素组合以双病位为主,占69.61%,单病位有27.45%,三病位及以上较少见,仅2.94%。病位在脾胃最多,其次是胃、肝胃。主要的病性要素有气虚(33.33%)、热(29.41)、气滞(28.92%)、湿(27.45%)、阳虚(26.47%),其次还有寒(15.20%)、血瘀(15.20%)、痰(5.39%)、阴虚(3.92%)。双病性组合较多,其次为单病性,三病性及以上组合较少见。实证96例(47.06%),虚证58例(28.43%),虚实夹杂证50例(24.51%),三组数据比较,有统计学差异。4.胃息肉证素分布与性别、年龄、Hp感染、息肉的数目、表面形态、病理组织无相关性(P0.05)。结论：胃息肉好发于41-70岁,女性多于男性。息肉以单发多见,单部位生长为主,以胃体、胃窦多见。Hp阳性率为12.84%。病理以炎性息肉为主,其次为胃底腺息肉。胃息肉病位证素主要有胃、脾、肝、胆；以双病位为主,病位在脾胃最多。病性证素以气虚、热、气滞、湿、阳虚为主,以双病性组合为主,实证多于虚证或虚实夹杂。胃息肉的证素分布与性别、年龄、Hp感染、息肉的数目、表面形态及病理组织均无相关性。
[Abstract]:Objective: to improve the clinical diagnosis and treatment system of gastric polyps by analyzing the distribution of syndromes and related factors in patients with gastric polyps. Methods: 257 patients with gastric polyps who met the diagnostic criteria were collected, and the four diagnosis information and age were recorded in detail. Referring to the "Syndrome differentiation scale" in Zhu Wenfeng's Dialectics of Syndromes, the relevant factors were extracted, the database was established, and the statistical analysis was made by using SPSS17.0 software. Results: 1. A total of 257 cases of gastric polyps, 100 males and 157 females, were collected. The ratio of male to female was 1: 1.57, the youngest was 14 years old. The maximum age was 85 years old. 77.04 cases had single gastric polyps, 22.96% had multiple polyps, the ratio was: 3.36% 1.The polyps grew mainly in one part. The second was the double part of the stomach: 100.109 cases had 42.41C, 81 cases had antrum 31.52C, 47 cases had cardia 18.29m, 41 cases had fundus 15. 95A, 9 cases had stomach horn, and there was statistical difference between men and women in the distribution of different parts of stomach, mainly gastric body and antrum, male was mainly gastric body and antrum, and there was no significant difference between male and female in the distribution of stomach body and gastric antrum, and there was a statistical difference between male and female in the distribution of stomach body and antrum, and there was a statistical difference between male and female in the distribution of stomach body and antrum. The pathological results showed that the inflammatory polyps were 65.76, followed by the fundus polyps 22.96, proliferative polyps 11.67 and adenomatous polyps 2.3333. 3.257 patients with gastric polyps could extract the syndromes. The rate of eliminating the evidence of the frequency distribution ratio of 2% was 2%, and the pathological results showed that the majority of the polyps were inflammatory polyps (65.76%), followed by the gastric fundus polyps (22.96%), the proliferative polyps (11.67%) and the adenomatous polyps (2.33%). It was found that the main syndromes of the disease were stomach (90.20), spleen (60.78), liver (19.61) and gallbladder (2.94). The combination of syndromes and syndromes consisted mainly of double diseases (69.61), single disease was 27.45m, three or more were rare, only 2.945.The most of the diseases were in the spleen and stomach, followed by the stomach. The main pathogenic factors of liver and stomach are Qi deficiency, Qi deficiency, Qi deficiency, Heat, Qi stagnation, Qi stagnation, Qi stagnation, Qi stagnation, Qi stagnation, Qi stagnation, 28.92U, dampness, 27.45m, Yang deficiency, 26.47m, Cold, 15.20g, Blood stasis, 15.20, sputum, Yin deficiency, 3.922B.The combination of double diseases is more, followed by single disease, followed by cold, blood stasis, blood stasis, blood stasis, phlegm, yin deficiency and 3.922.The combination of two diseases is more, followed by the single disease, the second is the single disease, the second is the single disease. The combination of three diseases and above is rare. There are 96 cases with syndrome of deficiency, 58 cases with deficiency syndrome, 58 cases with deficiency syndrome, and 50 cases with syndrome of deficiency and solid inclusion. There is a statistical difference between the three groups. The distribution and sex of gastric polyp syndromes, age and HP infection, the number of polyps, the appearance of polyps, Conclusion: gastric polyps are more common in 41-70 years old than in males. The polyps are mostly single polyps, mainly in the body of stomach and antrum. The positive rate of HP is 12.84% in gastric body and antrum. The main syndromes of gastric polyps were stomach, spleen, liver, and gallbladder. The most common syndromes were in the spleen and stomach. The syndrome was characterized by deficiency of qi, heat, stagnation of qi, dampness, deficiency of yang, and combination of two diseases. The distribution of syndromes in gastric polyps was not correlated with sex, age and HP infection, the number of polyps, surface morphology and pathological tissue.
【学位授予单位】：南京中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R259

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