改良型中药穴位敷贴的致敏性及有效性观察研究

发布时间：2018-03-08 04:23

本文选题：穴位贴敷法　切入点：剂型改进　出处：《河北中医》2017年01期 　论文类型：期刊论文

【摘要】：目的观察改良型中药穴位敷贴对膝骨关节炎治疗的致敏性及有效性。方法将80例膝骨关节炎患者随机分为2组,传统组40例采用传统中药穴位敷贴治疗,改良组40例采用改良型中药穴位敷贴治疗,2组疗程均为2周。采用西安大略和麦克马斯特大学(WOMAC)骨关节炎指数评价方案观察2组患者症状体征改善情况;统计2组治疗过程中贴敷部位皮肤瘙痒、红肿、灼热、蜕皮等过敏现象发生率及治疗结束后临床疗效。结果与传统组相比,改良组药物过敏率低(P0.05),过敏发生时间晚(P0.05),临床总有效率高(P0.05)。改良组治疗后WOMAC骨关节炎指数疼痛、关节僵硬、进行日常活动难度及总分均较本组治疗前降低,且低于传统组治疗后,比较差异均有统计学意义(P0.05);传统组治疗前后疼痛、关节僵硬、进行日常活动难度及总分无明显变化(P0.05)。结论改良型中药穴位敷贴有效的解决了中药穴位敷贴应用的局限,临床应用安全有效。
[Abstract]:Objective to observe the sensitivity and effectiveness of modified Chinese medicine acupoint application on knee osteoarthritis. Methods 80 patients with knee osteoarthritis were randomly divided into two groups. 40 patients in the modified group were treated with modified traditional Chinese medicine acupoint application for 2 weeks. The improvement of symptoms and signs was observed by using the Osteoarthritis Index of Western Ontario and McMaster University. The incidence of allergic phenomena such as pruritus, redness, swelling, burning and molting and clinical efficacy after treatment in the two groups were analyzed and compared with those in the traditional group. In the modified group, the drug hypersensitivity rate was lower than that in the control group (P 0.05A), and the hypersensitivity occurred late (P 0.05). The total clinical effective rate of the modified group was higher than that of the control group. After treatment, the WOMAC osteoarthritis index, joint stiffness, the difficulty of daily activities and the total score of the modified group were lower than those before the treatment. Compared with the traditional group, the difference was statistically significant (P 0.05), and the traditional group had pain and joint stiffness before and after treatment. There was no obvious change in the difficulty and total score of daily activities. Conclusion modified Chinese medicine acupoint application can effectively solve the limitation of traditional Chinese medicine acupoint application, and the clinical application is safe and effective.
【作者单位】：上海中医药大学附属曙光医院传统中医科;
【基金】：上海市中医药事业发展三年行动计划“研究型中医院建设”临床特色技术培育项目(编号:ZY3-CCCX-2-1003)
【分类号】：R244.9

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