渴乐宁胶囊治疗气阴两虚型糖尿病的临床效果观察

发布时间：2018-03-12 06:42

本文选题：渴乐宁胶囊　切入点：气阴两虚型　出处：《中药药理与临床》2017年03期 　论文类型：期刊论文

【摘要】：目的:观察渴乐宁胶囊治疗气阴两虚型糖尿病的临床效果。方法:研究对象为我院内分泌科在2015年1月~2016年9月期间收治的110例糖尿病患者,且均为气阴两虚型证候。随机原则分为两组(各55例),一组为对照组,该组给予常规药物进行治疗,另一组为观察组,另外给予渴乐宁胶囊进行治疗。分析两组疗效、血糖变化、胰岛素(INS)和C肽水平变化以及不良反应。结果:观察组经治疗后总有效率为92.73%,明显高于对照组76.36%。治疗后,观察组空腹血糖(FPG)、餐后2h血糖(2h PG)和糖化血红蛋白(Hb A1c)水平分别为(6.94±0.75mmol/L、9.46±0.97mmol/L、6.81±0.54%),均明显低于对照组(8.05±0.83mmol/L、12.11±1.52mmol/L、8.03±0.61%)。治疗后,观察组空腹状态下血清INS和C肽水平分别为(12.77±1.11μIU/ml、931.8±49.8pmol/L),均略低于对照组(13.27±1.18μIU/ml、952.4±52.1pmol/L),但组间差异均无统计学意义。(4)用药期间,观察组有16.36%的患者发生不良反应,略高于对照组10.91%,但组间差异无统计学意义。结论:渴乐宁胶囊可更好的调节气阴两虚型糖尿病患者血糖,且可减小发生高胰岛素血症的风险。
[Abstract]:Objective: to observe the clinical effect of Kailening capsule in treating diabetes mellitus with deficiency of qi and yin. Methods: 110 cases of diabetes mellitus were treated by Endocrinology Department from January 2015 to September 2016 in our hospital. The two groups were randomly divided into two groups (55 cases each, one group was the control group, the group was treated with routine drugs, the other group was the observation group, and the other group was treated with Kelening capsule). The curative effect of the two groups was analyzed. Results: the total effective rate after treatment in the observation group was 92.73, which was significantly higher than that in the control group 76.36. The fasting blood glucose levels of the observation group were 6.94 卤0.75mmol / L 9.46 卤0.97mmol / L 6.81 卤0.54g / L respectively, which were significantly lower than those of the control group (8.05 卤0.83mmol / L 12.11 卤1.52mmol / L 8.03 卤0.61g / L), and the levels of fasting blood glucose were 6.94 卤0.75mmol / L 9.46 卤0.97mmol / L 6.81 卤0.54g / L, respectively, which were significantly lower than those of the control group (8.05 卤0.83 mmol / L 12.11 卤1.52mmol / L 8.03 卤0.61g / L). The levels of serum INS and C-peptide in the observation group were 12.77 卤1.11 渭 INS / ml 931.8 卤49.8 pmol / L respectively, which were slightly lower than those in the control group (13.27 卤1.18 渭 mol / L, 952.4 卤52.1 pmol / L), but there was no significant difference between the two groups. Conclusion: Ke Lening capsule can better regulate blood sugar and reduce the risk of hyperinsulinemia in diabetic patients with deficiency of Qi and Yin.
【作者单位】：南阳医学高等专科学校;南阳医学高等专科学校第二附属医院;
【分类号】：R259

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