卵巢早衰中医体质与生命质量的相关性研究

发布时间：2018-03-12 10:01

本文选题：卵巢早衰　切入点：生命质量　出处：《成都中医药大学》2016年硕士论文　论文类型：学位论文

【摘要】：目的：研究卵巢早衰患者的中医体质及生命质量特征,探讨体质与生命质量的相关性,以提升对本病的关注度,为临床调整偏颇体质以提高POF患者生命质量提供客观依据。方法：通过对POF患者进行横断面现场调查,以自填式或问答式方法,填写方积乾教授的《中文版SF-36》及王琦教授的《中医体质调查量表》,并结合病案资料,收集相关的临床资料。根据SF-36评分标准和中医体质分类判定标准,获得POF患者生命质量各维度评分和体质分型的相关数据。对相关数据用SPSS20.0进行统计分析,得出POF患者中医体质和生命质量特征的统计数据,探讨两者的相关性。结果：1.221例POF患者的体质类型中,平和质18例,占8.14%；偏颇体质203例,占91.86%；偏颇体质中,气虚质明显高于其他体质,占22.62%,气郁质、阴虚质相对也较多,分别占20.36%、15.84%；该人群单纯体质仅有10例,211例(95.48%)患者为复合体质,兼夹体质中气虚质和气郁质较多。2.221例POF患者生命质量各维度得分(均值与标准差)由低到高为情感职能(51.31±34.43)、心理健康(60.19±14.05)、活力(61.35±15.88)、总体健康(62.02±11.25)、躯体疼痛(77.28±18.41)、生理职能(80.24±25.69)、社会功能(81.95±16.48)、生理机能(93.77±8.92)。3.POF患者不同体质类型在SF-36各维度得分不同。平和质在生命质量各维度得分均优于其他偏颇体质。活力方面,其他偏颇体质得分均比平和质低(P0.05)；心理健康上,气郁质、痰湿质和特禀质的得分比平和质低(P0.05)；在躯体疼痛上,气郁质、血瘀质、阴虚质、痰湿质和特禀质得分比平和质低(P0.05)；社会功能方面,气郁质、阴虚质、湿热质和痰湿质得分均比平和质低(P0.05)；情感职能方面,气郁质、阳虚质和特禀质得分比平和质低(P0.05)；生理职能方面,气郁质、阴虚质、痰湿质、血瘀质和特禀质得分比平和质低(P0.05)；生理机能方面,阴虚质、湿热质、痰湿质和特禀质得分比平和质低(P0.05)；总体健康方面,阴虚质和血瘀质得分比平和质低(P0.05)。4.POF患者中医体质和生命质量相关性逐步回归结果显示：偏颇体质中,阳虚质对生命质量的5个维度有损害,对生命质量的危害最大；生命质量8个维度在不同体质中受损害最多的是心理健康；气虚质与活力呈负相关(P0.01)；阳虚质与躯体疼痛、社会功能、情感职能、生理功能、总体健康呈负相关(P0.01)；阴虚质与心理健康、躯体疼痛、社会功能、总体健康呈负相关(P0.01)；血瘀质与心理健康、躯体疼痛、情感职能呈负相关(P0.01)；气郁质与心理健康呈负相关(P0.01)。结论：1.POF患者体质类型特点为偏颇体质占大多数,而平和质较少；偏颇体质中以气虚质最多,其次为气郁质和阴虚质；该人群体质较为复杂,大多为复合体质。2.POF患者的生命质量有所下降,尤其是心理健康和情感职能方面。3.POF患者的中医体质和生命质量间存在一定的相关性,阳虚质对生命质量的影响较大。
[Abstract]:Objective: to study the characteristics of TCM constitution and quality of life (QOL) in patients with premature ovarian failure (POF), and to explore the correlation between physique and quality of life (QOL) in order to increase the attention to the disease. Objective basis was provided for clinical adjustment of biased physique to improve the quality of life of patients with POF. Methods: through cross-sectional field investigation of patients with POF, self-filling or question-and-answer method was used. Fill in Professor Fang Jigan's "Chinese version SF-36" and Professor Wang Qi's "TCM physique investigation scale", and combine the medical record data to collect the relevant clinical data. According to the SF-36 score standard and the traditional Chinese medicine constitution classification standard, The relevant data of quality of life (QOL) score and constitution classification of POF patients were obtained. The statistical data of TCM physique and quality of life of POF patients were obtained by SPSS20.0 statistical analysis. Results among 1.221 cases of POF, 18 cases were mild (8.14%); 203 cases were biased (91.86%); in partial constitution, qi deficiency was significantly higher than other constitution (22.622%), Qi stagnation, yin deficiency were also relatively more. The proportion of the patients was 20.360.454.The simple constitution of this group was only 10 cases (211 cases). The scores of quality of life (mean and standard deviation) in 2.221 patients with POF were 51.31 卤34.43, 60.19 卤14.05, 61.35 卤15.88, 62.02 卤11.2581, 77.28 卤18.41, 80.24 卤25.69, respectively. The scores of different physique types of patients with SF-36 were different in each dimension of SF-36, and the scores of mild quality in all dimensions of life quality were superior to those of other biased physiques. The scores of other biased physiques were lower than those of calmness (P 0.05); in mental health, the scores of qi stagnation, phlegm dampness and intrinsic quality were lower than those of mild quality; in somatic pain, Qi Yu, blood stasis, yin deficiency, The scores of phlegm dampness and intrinsic quality were lower than that of mild quality (P 0.05); in social function, the scores of qi, yin deficiency, damp-heat and phlegm were all lower than those of peaceful quality (P 0.05); in emotional function, qi was depressed. The scores of Yang deficiency and intrinsic quality were lower than that of mild quality (P 0.05); in physiological function, the scores of qi stagnation, yin deficiency, phlegm and dampness, blood stasis and intrinsic quality were lower than those of peaceful quality (P 0.05); in physiological function, yin deficiency, dampness and heat, The scores of phlegm dampness and intrinsic quality were lower than that of calmness. In general health, the scores of yin deficiency and blood stasis were lower than those of calming. 4. The results of stepwise regression of the relationship between TCM constitution and quality of life of POF patients showed that: in biased constitution, Yang deficiency causes damage to 5 dimensions of quality of life, which is the most harmful to quality of life; eight dimensions of quality of life are most damaged by mental health in different physique; qi deficiency is negatively correlated with vitality (P 0.01); Yang deficiency is associated with physical pain. Social function, emotional function, physiological function and overall health were negatively correlated with mental health, body pain, social function and overall health; blood stasis was negatively correlated with mental health, body pain, social function and total health; blood stasis was associated with mental health and somatic pain. Negative correlation was found between emotional function and mental health. Conclusion: 1. The characteristics of physical types of POF patients are that the majority of physical types are biased, but the quality of peace is less, qi deficiency is the most, followed by deficiency of qi and yin deficiency. The quality of life of POF patients decreased, especially in mental health and emotional function. 3. There was a certain correlation between TCM constitution and quality of life of POF patients. Yang deficiency quality has a great effect on quality of life.
【学位授予单位】：成都中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R271.9

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