生慧益智汤对轻、中度老年性痴呆患者认知功能和生活能力的影响

发布时间：2018-03-12 15:14

本文选题：老年性痴呆　切入点：生慧益智汤　出处：《中华中医药杂志》2017年07期 　论文类型：期刊论文

【摘要】：目的:观察中药生慧益智汤联合盐酸多奈哌齐对轻、中度老年性痴呆患者认知功能和日常生活能力的影响。方法:60例轻、中度老年性痴呆患者,分为对照组和治疗组,每组30例。对照组给予盐酸多奈哌齐,每日5mg,睡前口服;治疗组在对照组的的基础上联合中药生慧益智汤,每剂煎药200m L,分早、晚2次口服,每日1剂。分别于治疗前及治疗后6个月,进行认知功能和日常生活能力的评价。结果:两组治疗前后比较,治疗组简易智能精神状态量表(MMSE)评分有明显提高(P0.01),且优于对照组(P0.05);两组社会功能活动问卷(FAQ)评分下降显著(P0.05)。结论:生慧益智汤联合盐酸多奈哌齐能改善轻、中度老年性痴呆患者认知功能和日常生活能力,对老年性痴呆的治疗具有一定的疗效。
[Abstract]:Objective: to observe the effect of Shenghui Yizhi decoction combined with Donepezil Hydrochloride on cognitive function and daily living ability of mild and moderate senile dementia patients. Methods: 60 patients with mild and moderate senile dementia were divided into control group and treatment group. There were 30 cases in each group. The control group was given Donepezil Hydrochloride, 5 mg daily, before bedtime, while the treatment group combined with Shenghui Yizhi decoction, 200 mL per dose of decoction, was taken orally in the morning, 2 times in the evening, on the basis of the control group, the treatment group was treated with Shenghui Yizhi decoction. 1 dose per day. Cognitive function and ADL were evaluated before and 6 months after treatment. Results: two groups were compared before and after treatment. The MMSE score of the treatment group was significantly higher than that of the control group (P 0.05), and the scores of the two groups decreased significantly (P 0.05). Conclusion: Shenghui Yizhi decoction combined with Donepezil Hydrochloride can improve the mild degree. The cognitive function and daily living ability of moderate senile dementia patients have certain curative effect on the treatment of senile dementia.
【作者单位】：中日友好医院;
【分类号】：R277.7

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