维医分型与晚期食管癌放化疗疗效的关系

发布时间：2018-03-15 08:39

本文选题：维医分型　切入点：晚期食管癌　出处：《新疆医科大学》2016年硕士论文　论文类型：学位论文

【摘要】：目的:根据维吾尔医学“体液论”,将恶性肿瘤分为异常黑胆质型和非异常黑胆质型,本研究旨在探讨维医分型与食管癌放化疗疗效的关系。方法:选择300例IIIB-IV期食管癌患者,按照维医分型标准对其放化疗前后进行分型,并进行6个月及以上时间随访,通过观察临床症状及CT等检查结果评价其疗效(评价指标包括:有效、稳定和进展),通过再次维医分型观察患者的体液类型变化。结果:共有284例患者完成6个月及以上时间随访,结果显示:1.不论是治疗前还是治疗后,异常黑胆质型均为晚期食管癌患者的主要体液类型,其在汉、维及哈族间所占比例分别为:81.05%、72.92%、78.49%(治疗前),90.53%、86.46%、91.40%(治疗后),各民族间分布无明显统计学差异(2?=1.895,P0.05;?2=1.399,P0.05);2.异常黑胆质型食管癌患者与特定饮食环境有关,其中22.5%有靠山居住史,24.3%喜干寒饮食,12.9%既往常有焦虑,11.6%既往常有急躁、易怒等情绪长期存在;3.异常黑胆质型与非异常黑胆质型患者的放化疗疗效有明显统计学差异(?=2.286,P0.05),其中异常黑胆质型患者的有效率偏低(6.82%VS 17.19%)、进展率偏高(51.82%VS 39.06%);4.治疗前后患者的维医分型发生了变化,异常黑胆质型体液增多,此差异具有统计学意义(2?=15.209,P0.05)。结论:异常黑胆质型为晚期食管癌患者的主要体液类型,其形成与患者的饮食、情绪及生活环境有关;维医分型可作为晚期食管癌放化疗疗效的评价方法之一。
[Abstract]:Objective: according to the "humoral theory" of Uygur medicine, malignant tumors were divided into abnormal black bile type and non-abnormal black bile type. The purpose of this study was to investigate the relationship between the classification of Uygur medicine and the curative effect of radiotherapy and chemotherapy for esophageal carcinoma. Methods: three hundred patients with esophageal carcinoma in IIIB-IV stage were selected. According to the criteria of Uygur Medical Classification, the patients were classified before and after radiotherapy and chemotherapy, and followed up for 6 months or more. The curative effect was evaluated by observing the clinical symptoms and CT findings. Stable and progressive, the changes of body fluid types were observed by re-classification. Results: a total of 284 patients were followed up for 6 months or more. The results showed that: 1. Whether before or after treatment, Abnormal black gallbladder type is the main humoral type in patients with advanced esophageal cancer. The proportions of abnormal melanoglycoid type in Han, Uygur and Kazakh ethnic groups are 78.49 and 78.49, respectively. (before treatment, 90.53 and 86.46%, 91.40%). (after treatment, there is no significant difference in distribution between different ethnic groups. 2? P0.05? 2. Abnormal black bile type esophageal cancer patients were related to specific dietary environment, of which 22.5% had a living history of 24.3%, 12.9% of them had anxiety and 11.6% had anxiety and were often irritable in the past. Irritability and other emotions exist for a long time. 3. Are there significant differences in the effects of radiotherapy and chemotherapy between the patients with abnormal black gallbladder type and non-abnormal black bile type? The effective rate of patients with abnormal melanoglycoid type was lower than 6.82 vs 17.19, and the rate of progress was higher than 51.82% vs 39.060.The types of the patients with abnormal melanoglycoid type had changed before and after treatment, and the body fluid of abnormal melanoglycoid type increased, the difference was statistically significant (P < 0.05). Conclusion: abnormal black bile type is the main humoral type of patients with advanced esophageal cancer, and its formation is related to the diet, emotion and living environment of the patients, and it can be used as one of the evaluation methods for the curative effect of radiotherapy and chemotherapy for advanced esophageal carcinoma.
【学位授予单位】：新疆医科大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R29

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