针灸治疗视神经萎缩有效性系统评价及网状Meta分析

发布时间：2018-03-20 23:11

本文选题：视神经萎缩　切入点：针灸　出处：《北京中医药大学学报》2017年05期 　论文类型：期刊论文

【摘要】：目的采用基于频率统计法数据填补策略的网状Meta模型分析评价针灸治疗视神经萎缩的临床疗效。方法计算机检索Cochrane Library、Pub Med、EMbase、AMED、Nature、Science Online、World Sci Net、中国生物医学文献光盘数据库(CBM)、相关期刊论文(CNKI)、万方资源数据库建库至2016年6月收录的随机对照试验/半随机对照试验(RCT/CCT)文献,由2名研究者按照Cochrane手册5.1.0标准对每项纳入的研究进行质量和偏倚风险评估。结果共纳入16项研究、1 369例样本。网状Meta分析结果显示,每种治疗方法疗效"最佳"的可能性分别是:西药(10.5%)、针刺(5.9%)、针刺+艾灸(4.4%)、耳穴+中药(4.7%)、电针(8.0%)、针刺+中西药(4.9%)、艾灸+西药(3.2%)、电针+中西药(4.3%)、中西药(10.1%)、中药(6.7%)、针刺+西药(3.4%),西药疗效最佳。针刺结合西药相较于单纯使用西药具有优势(P0.05)。由于所纳入文献均未描述不良情况的发生,使得安全性评价无法确实得出。对于本病针灸治疗机制的现代医学研究相对较少,尚无法对其现代医学机制作出评判。结论西药、中西药、电针为治疗本病的最佳疗法可能性大,但确切的结论尚需要高质量的临床研究进一步验证。
[Abstract]:Objective to evaluate the clinical efficacy of acupuncture and moxibustion in the treatment of optic atrophy by using a reticular Meta model based on the filling strategy of frequency statistics. Methods to search Cochrane LibraryPub Medbase for Natural Science OnlineWorld Sci Net. China Journal Full-text Database CNKI, Wanfang Resources Database, RCT / CCT documents collected in June 2016, The quality and bias risk of each included study was assessed by two researchers according to the Cochrane Manual 5.1.0. The results included a total of 1,369 samples of 16 studies. The mesh Meta analysis showed that, The possibility of "the best" effect of each treatment is as follows: 10. 5% of western medicine, 5. 9 points of acupuncture, 4. 4% of acupuncture, 4. 7% of acupuncture, 4. 7% of Chinese medicine, 4. 7% of electroacupuncture, 4. 9% of Chinese and western medicine, 3. 22% of moxibustion, 4. 33% of Chinese and western medicine, 10. 1% of Chinese and western medicine, 6. 7% of Chinese medicine and 6. 7% of acupuncture. Western medicine has the best curative effect. Acupuncture combined with western medicine has an advantage over the use of western medicine alone. Since none of the literature involved described the occurrence of adverse conditions, The modern medical research on acupuncture and moxibustion treatment mechanism of this disease is relatively few, and it is impossible to judge its modern medical mechanism. Conclusion Western medicine, traditional Chinese medicine, western medicine, Electroacupuncture is the best treatment for this disease, but the exact conclusion needs to be further verified by high quality clinical research.
【作者单位】：广州中医药大学针灸康复临床医学院;
【基金】：国家重点基础研究发展计划(973计划)项目(No.2012CB518504)~~
【分类号】：R246.82

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