胡春申教授治疗血管性痴呆学术思想及临床经验

发布时间：2018-03-27 05:22

本文选题：血管性痴呆　切入点：肾虚痰瘀型　出处：《成都中医药大学》2016年硕士论文

【摘要】：目的：通过对中医文献进行数据挖掘,结合临床研究,采取从理论探讨到临床实践检验的研究思路,探寻出中医对血管性痴呆病机认识及证治规律,以提高中医对血管性痴呆的临床证治水平。方法：1、文献研究：收录古今文献后采用频数分析、关联规则数据挖掘方法,对血管性痴呆的常见症状、证型、方药进行分析,对血管性痴呆的病因病机、证型分布、用药特点进行理论探讨,对出现频率最高的肾虚痰瘀证在血管性痴呆的发病过程进行理论探讨。2、临床研究：收集胡春申教授临床治疗有效的病例62例,并对处方进行频数分析。结果：1、通过对古代与现代文献进行数据挖掘我们发现眩晕、反应迟钝、耳鸣、健忘、注意力不集中为血管性痴呆的常见症状,这与现代的诊断标准基本一致,表明古代文献收录的病种与血管性痴呆是基本相吻合的。2、频次统计可以直观的看出病位30次的依次为肾、心、脾胃。病性40次的有阳虚、痰、血瘀、气虚、血虚。由此大致可以得知该病定位主要责之与肾、心、脾三脏,在病性主要责之阳虚、痰、血瘀、气血亏虚。所以我们可以将病机简单的概括为“痰、瘀、虚”三个方面。3、古今文献在实证中证型无差异,而在虚证与虚实夹杂证中古今两两证型比较p0.05。表明现代文献中对血管性痴呆的中医认识更侧重于实证即痰蒙心窍证、瘀血阻络证、肝胆湿热证,而古代文献中辨证是虚实并重。4、通过药证关联筛选出频次高出100的药物分别有：人参、川芎、丹参、赤芍、黄芪、茯苓、法半夏、红花、浙贝母、苍术、防己。5、总结出胡××教授治疗血管性痴呆常用人参、白术、茯苓、山栀、丹参、赤芍、郁金、葛根的临床经验；脑府宜开通,不易阻塞；宜升阳不易开窍的学术思想。
[Abstract]:Objective: through the data mining of TCM literature, combined with clinical research, the research ideas from theory discussion to clinical practice test were adopted to find out the understanding of TCM to vascular dementia and the rule of syndrome and treatment. In order to improve the clinical treatment level of vascular dementia in traditional Chinese medicine. Methods: literature study: frequency analysis and association rule data mining method were used to analyze the common symptoms, syndromes and prescriptions of vascular dementia. The etiology and pathogenesis of vascular dementia, the distribution of syndromes, and the characteristics of drug use were discussed theoretically. The most frequent occurrence of kidney deficiency and phlegm stasis syndrome in the pathogenesis of vascular dementia was discussed theoretically. 2. Clinical study: 62 cases of effective clinical treatment by Professor Hu Chun Shen were collected. And we analyzed the frequency of the prescription. Results: 1, through the data mining of ancient and modern literature, we found that vertigo, slowness, tinnitus, forgetfulness, and inattention were common symptoms of vascular dementia. This is basically consistent with the modern diagnostic criteria, indicating that the diseases recorded in the ancient literature are basically consistent with vascular dementia. The frequency statistics can intuitively show that the diseased position of 30 times is the kidney, the heart, the spleen and stomach, and the diseased 40 times have yang deficiency and phlegm. Blood stasis, qi deficiency, and blood deficiency. From this we can roughly know that the disease is mainly responsible for the kidney, heart and spleen, and for the deficiency of yang, phlegm, blood stasis and deficiency of qi and blood. So we can simply summarize the pathogenesis as "phlegm, blood stasis, and deficiency of qi and blood." There is no difference in the syndromes between ancient and modern literature, but there is a comparison between the two syndromes of deficiency syndrome and deficiency syndrome, p0.05. It shows that the TCM understanding of vascular dementia in modern literature is more focused on the empirical evidence, that is, phlegm and heart resuscitation syndrome, which is the syndrome of phlegm and heart resuscitation. The syndrome of stagnation of blood and obstruction of collaterals, dampness of liver and gallbladder, while in the ancient literature, the syndrome differentiation is deficiency and reality as well as emphasis on .4.The drugs with a frequency of 100 times higher were screened out by the association of drug syndromes: ginseng, Rhizoma Chuanxiong, Salvia miltiorrhiza, Radix Paeoniae Alba, Astragalus, Poria cocos, Rhizoma Ternate, Carthamus thunbergii, Atractylodes Atractylodes, Fangji. 5, summarize the common clinical experience of Prof. Hu 脳脳 X in the treatment of vascular dementia, such as ginseng, Atractylodes macrocephala, Poria cocos, Shan Zhi, Salvia miltiorrhiza, Radix Paeoniae Alba, Tujin, Pueraria kudzu;
【学位授予单位】：成都中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R249;R277.7

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