麝香通心滴丸对稳定型心绞痛（痰热瘀阻型）患者中医证候影响的研究

发布时间：2018-03-28 20:32

本文选题：麝香通心滴丸　切入点：稳定型心绞痛　出处：《黑龙江中医药大学》2017年硕士论文

【摘要】：目的:采用随机、双盲、安慰剂对照方法观察麝香通心滴丸对冠心病稳定型心绞痛(痰热瘀阻型)患者中医证候和平板运动试验结果的影响,以评价麝香通心滴丸的有效性,为临床治疗稳定型心绞痛(痰热瘀阻型)提供依据。方法:选择2015年5月至2016年7月来自黑龙江中医药大学附属第一医院门诊的患者,均自愿签署患者知情同意书。经过2周导入洗脱期,将符合纳入标准的20例,按照1:1随机分为2组,其中试验组与对照组分别10例。两组患者均在西医冠心病心绞痛标准化治疗的基础上,试验组以麝香通心滴丸口服,对照组以麝香通心滴丸安慰剂口服,一次2丸,一日3次,共56±7天。记录试验前后患者基本生命体征、中医证候积分表、标准BRUCE运动平板试验指标。结果:1、在中医证候总积分方面,试验组治疗后明显低于治疗前,差异具有统计学意义(P0.05)。2、在中医证候积分总有效率、单项症状有效率(除心悸、形体肥胖)方面,试验组在治疗后均高于对照组,差异具有统计学意义(P0.05)。3、在ST段下降最大幅度和(mv)方面,试验组在治疗后明显低于治疗前,差异有统计学意义(P0.05);治疗后,试验组明显低于对照组,差异有统计学意义(P0.05)。结论:1、麝香通心滴丸能改善稳定型心绞痛(痰热瘀阻型)患者的中医证候。2、麝香通心滴丸能改善冠心病稳定型心绞痛(痰热瘀阻型)患者平板运动试验中的缺血程度。
[Abstract]:Objective: to observe the effect of Shexiang Tongxin dropping pills on TCM syndromes and treadmill exercise test results in patients with stable angina pectoris (phlegm and heat stasis type) of coronary heart disease (CHD) by randomized, double-blind and placebo control methods, and to evaluate the effectiveness of Shexiang Tongxin dropping pills. Methods: from May 2015 to July 2016, patients from the first affiliated Hospital of Heilongjiang University of traditional Chinese Medicine were selected from outpatient clinic of the first affiliated Hospital of Heilongjiang University of traditional Chinese Medicine to provide the basis for clinical treatment of stable angina pectoris (phlegm and heat stasis type). 20 patients who met the inclusion criteria were randomly divided into 2 groups according to 1:1. There were 10 cases in the trial group and 10 cases in the control group. On the basis of the standardized treatment of angina pectoris in western medicine, the experimental group was given Shexiang Tongxin dropping pills orally, and the control group was given Shexiang Tongxin dropping pills placebo, 2 pills once a day, 3 times a day. A total of 56 卤7 days. Before and after the test, the patients' basic vital signs, TCM syndromes integral table and standard BRUCE exercise plate test indexes were recorded. Results: 1. In the total score of TCM syndromes, the experimental group was significantly lower after treatment than before treatment. The difference was statistically significant (P 0.05). The total effective rate of TCM syndromes integral and the effective rate of single symptom (except palpitation, body obesity) in the experimental group were higher than those in the control group after treatment. The difference was statistically significant (P0.05U. 3). In the aspect of the maximum decrease of St segment and MV), the experimental group was significantly lower than that before treatment, the difference was statistically significant (P0.05), after treatment, the trial group was significantly lower than the control group. The difference was statistically significant (P 0.05). Conclusion:% 1, Shexiang Tongxin dropping pill can improve TCM syndrome of stable angina pectoris (phlegm heat stasis type), and Shexiang Tongxin dropping pill can improve coronary heart disease stable angina pectoris (phlegm heat stasis type) patients. The degree of ischemia in the plate exercise test.
【学位授予单位】：黑龙江中医药大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R259

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