针刺治疗抗精神分裂症药物引起的心肌缺血的临床观察

发布时间：2018-03-31 23:33

  本文选题：针刺　切入点：抗精神分裂症药物　出处：《南京中医药大学》2016年硕士论文

【摘要】：本研究采用针刺的方式治疗抗精神分裂症药物引起的心肌缺血,以心肌肌钙蛋白及心电图改变作为观察指标,以此评价针刺相关穴位治疗抗精神分裂症药物引起的心肌缺血的疗效,寻找治疗抗精神分裂症药物引起的心肌缺血的最佳方法,为丰富针刺治疗疾病的方法提供思路。方法：根据心肌缺血诊断标准及心电图检查结果,收集南京市青龙山精神病院1-20病区2014年-2015年收治的精神病人中服用抗精神分裂症药物后出现心肌缺血的患者58人,根据数字随机表按1：1的比例,将患者随机分为治疗组28例,对照组30例。对照组仅给予药物对症治疗,治疗组给予药物对症治疗结合针刺治疗。针刺方法为：隔日行针1次,每次30min,20d为1疗程,间隔10d后进行第2疗程。治疗前后,对患者临床主要症状评分,心电图情况,肌钙蛋白情况进行对照观察。结果：1.两组患者治疗前和第1疗程后临床症状自评分比较均无显著性差异(P0.05)；第2疗程治疗后,治疗组得分较对照组显著降低(P0.05)；两组患者得分在治疗前、第1疗程后和第2疗程后得分比较有显著性(P0.05),且得分有降低的趋势。2.两组患者治疗前、第1疗程后2个时点上T波改变总值(∑T)比较均无差异(P0.05),到第2疗程后时,治疗组ET较对照组出现显著性差异(P0.05)；对于治疗组,治疗前、第1疗程后和第2疗程后3个时点之间比较∑T有显著性差异(P0.05),而对照组则无差异。3.两组患者治疗前肌钙蛋白含量比较无差异(P0.05)；第1疗程后,治疗组CTnT较对照组已有差异(P0.05),到第2疗程后时,治疗组CTnT较对照组有显著降低(P0.05)；对于治疗组,治疗前、第1疗程后和第2疗程后肌钙蛋白含量组内比较有显著降低(P0.05),而对照组无明显差异,但有降低趋势。结论：应用药物结合针刺治疗抗精神分裂症药物引起的心肌缺血的方法安全有效,其总体疗效优于单纯药物一般对症治疗。
[Abstract]:In this study, acupuncture was used to treat myocardial ischemia induced by antipsychotic drugs. The changes of cardiac troponin and electrocardiogram were used as indexes.The purpose of this study was to evaluate the therapeutic effect of acupuncture on myocardial ischemia induced by antipsychotic drugs, to find the best method for treating myocardial ischemia caused by antipsychotic drugs, and to provide ideas for enriching the methods of acupuncture in treating diseases.Methods: according to the diagnostic criteria of myocardial ischemia and the results of electrocardiogram examination, 58 patients with myocardial ischemia were collected from 2014 to 2015 in Qinglongshan Psychiatric Hospital from 2014 to 2015.The patients were randomly divided into treatment group (n = 28) and control group (n = 30).The control group was only treated with drug therapy and the treatment group with acupuncture therapy.The method of acupuncture was as follows: acupuncture was given once every other day, 30 minutes and 20 days each time as a course of treatment, and the second course of treatment was carried out after the interval of 10 days.Before and after treatment, the main clinical symptoms, electrocardiogram and troponin were observed.The result is 1: 1.There was no significant difference in the self-score of clinical symptoms between the two groups before treatment and after the first course of treatment, and after the second course of treatment, the scores of the treatment group were significantly lower than those of the control group, and the scores of the two groups were significantly lower than those of the control group.The scores after the first course of treatment and after the second course of treatment were significantly higher than that after the second course of treatment, and the score showed a tendency of decreasing.Before and after the first course of treatment, there was no difference in the total value of T wave change (鈭，

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