清鼻止鼾汤治疗儿童腺样体肥大（痰瘀互结型）的临床研究

发布时间：2018-04-01 00:12

本文选题：腺样体肥大　切入点：痰瘀互结型　出处：《黑龙江中医药大学》2017年硕士论文

【摘要】：目的:观察清鼻止鼾汤治疗儿童腺样体肥大(痰瘀互结型)的临床疗效。方法:将160例腺样体肥大患儿分为两组,其中治疗组120例,对照组40例,治疗组治以活血祛瘀、化痰散结,口服清鼻止鼾汤,一日2次;对照组口服鼻渊通窍颗粒并鼻腔吸入糠酸莫米松。疗程均为3周。记录2组用药前后的症状体征,拍摄鼻咽部X线侧位片或CT,计算A/N值,进行统计学分析。结果:治疗组,因患儿服药困难脱落4例,服药中途病情严重加用其他药物视为无效病例4例,完成记录112例;对照组因病情严重加用其他药物视为无效病例9例,完成记录31例。治疗组总有效率为96.55%,对照组总有效率为77.50%,差异有统计学意义,显示在疗效方面治疗组明显优于对照组。对治疗前后两组中医证候积分、中医主要症状总积分进行比较,P值0.05,有统计学意义,治疗组优于对照组;对治疗前后两组中医主要症状单项积分进行比较,其中鼻塞、睡眠打鼾、睡眠张口、睡眠鼻窒积分P值0.05,有统计学差异,治疗组的症状改善明显优于对照组。对鼻咽部侧位X线片A/N值这一客观指标进行比较,P值0.05,有统计学差异,治疗组优于对照组。结论:1.清鼻止鼾汤治疗儿童腺样体肥大(痰瘀互结型)具有较好的临床疗效,明显优于口服鼻渊通窍颗粒并鼻腔吸入糠酸莫米松。2.清鼻止鼾汤能明显改善痰瘀互结型腺样体肥大患儿鼻塞、睡眠打鼾、睡眠张口等症状,且能明显降低儿童鼻咽部X线侧位片或CT的A/N值这一客观指标。3.清鼻止鼾汤治疗儿童腺样体肥大(痰瘀互结型)具有良好的安全性,未见明显不良反应。
[Abstract]:Objective: to observe the clinical effect of Qingbizhisu decoction on children's adenoid hypertrophy (phlegm and blood stasis type). Methods: 160 children with adenoid hypertrophy were divided into two groups: 120 cases in treatment group and 40 cases in control group. Huatan Sanjie, oral Qingbeizhi decoction, 2 times a day; control group, oral Biyuan Tongqiao granule and nasal cavity inhaled momethasone furoate. The course of treatment was 3 weeks. The symptoms and signs of the two groups before and after treatment were recorded. Results: in the treatment group, 4 cases were lost because of difficulty in taking medicine, 4 cases were treated with other drugs and 4 cases were treated with other drugs, 112 cases were recorded. In the control group, the total effective rate was 96.55 and the total effective rate in the control group was 77.50, the difference was statistically significant. The results showed that the treatment group was obviously superior to the control group in curative effect. The score of TCM syndrome and the total integral of main symptoms of TCM were compared between the two groups before and after treatment (P = 0.05), which was statistically significant, and the treatment group was superior to the control group. The main symptoms of traditional Chinese medicine before and after treatment were compared between the two groups, including nasal congestion, sleep snoring, sleep mouth opening, sleep nasal smothering score P value 0.05, there was statistical difference. The improvement of symptoms in the treatment group was obviously better than that in the control group. Conclusion the treatment group is superior to the control group. Conclusion Qingbizhisu decoction has good clinical effect in treating children with adenoid hypertrophy (phlegm and blood stasis type). It was better than taking Biyuan Tongqiao granule and inhaling momethasone furoate in nasal cavity. Qingbeizu decoction could obviously improve the symptoms of nasal congestion, sleep snoring, sleep opening and so on in children with hypertrophy of sputum and blood stasis. The objective index of A- N value of lateral radiographs or CT of nasopharynx in children was significantly decreased. 3. Qingbeizhi decoction had good safety in treating children with adenoid hypertrophy (phlegm and blood stasis type), and no obvious adverse reactions were found in the treatment of children with adenoid hypertrophy (phlegm and blood stasis type).
【学位授予单位】：黑龙江中医药大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R276.1

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