灸药结合治疗强直性脊柱炎（肾阳亏虚证）的临床研究

发布时间：2018-04-05 07:53

本文选题：强直性脊柱炎　切入点：肾阳亏虚证　出处：《辽宁中医药大学》2016年硕士论文

【摘要】：目的:通过比较单纯药物疗法与灸药结合疗法治疗强直性脊柱炎(肾阳亏虚证)临床疗效的差异性,探究灸药结合治疗强直性脊柱炎(肾阳亏虚证)短期(12周)及长期(停药后12周)疗效的特点,为临床中医综合治疗强直性脊柱炎提供更广泛的思路。材料与方法:将60例符合本研究标准的强直性脊柱炎病例,随机分为对照组、治疗组,各30例,治疗12周。对照组采用口服独活寄生汤加减治疗;治疗组在中药对照组治疗的基础上,加灸足三里(双)、食窦、神阙、关元、命门、阿是穴。观察治疗前后、停药12周以后的临床指标(症状、体征)、生化指标(血沉、C反应蛋白)的变化情况。并检测相关安全指标,以了解用药安全性。采用SPSS17.0软件进行统计学处理。结果:1.治疗前后:两组患者的临床指标与生化指标均有明显改善,具有统计学意义(P0.05),提示治疗组与对照组均有效。2.治疗前后:治疗组的临床指标和生化指标改变优于对照组,具有统计学意义(P0.05),提示治疗组在改善强直性脊柱炎临床症状和生化指标方面优于对照组。3.治疗前后:治疗组总有效率虽高于对照组,但无统计学意义(P0.05),提示对照组、治疗组在改善强直性脊柱炎临床指标、生化指标的近期疗效方面无显著差异。4.停药前后:治疗组临床指标变化不明显,无统计学意义(P0.05);对照组临床指标变化明显,具有统计学意义(P0.05),提示治疗组远期疗效优于对照组。结论:1.艾灸联合中药疗法在改善强直性脊柱炎(肾阳亏虚证)的临床症状、体征以及生化指标方面优于单纯中药疗法。2.艾灸联合中药疗法治疗强直性脊柱炎(肾阳亏虚证)的远期疗效优于单纯中药疗法。
[Abstract]:Objective: To compare the simple drug therapy and moxibustion combined with medicine therapy in the treatment of ankylosing spondylitis (kidney yang deficiency) differences in clinical efficacy, combined with the inquiry moxibustion in the treatment of ankylosing spondylitis (kidney yang deficiency) short term (12 weeks) and long-term (12 weeks after drug withdrawal) special curative effect, to provide a wider range of ideas for clinical TCM treatment of ankylosing spondylitis. Materials and methods: 60 cases meet the criteria of ankylosing spondylitis were randomly divided into control group, treatment group, 30 cases each, for 12 weeks. The control group with oral administration of Duhuojisheng Decoction in the treatment group; the control group of Chinese medicine treatment. Plus moxibustion at Zusanli point (double), Shidou, Shenque, Guanyuan, Mingmen, Ashi. Observed before and after treatment, the clinical index after discontinuation of 12 weeks (symptoms and signs), biochemical indexes (ESR, C reactive protein) change. And detecting the relevant safety indicators, in order to understand the medication Safety was analyzed by SPSS17.0 statistical software. Results: 1. before and after treatment: clinical indexes and biochemical indexes were two groups were significantly improved, with statistical significance (P0.05), before and after the prompt treatment group and control group were effective in the treatment of.2.: clinical and biochemical indexes of treatment group changes better than the control group, with statistical significance (P0.05), the treatment group before and after the improvement of ankylosing spondylitis clinical symptoms and biochemical indexes than the control group.3. treatment: the total effective rate of treatment group was higher than control group, but no statistical significance (P0.05), suggesting that the control group, the treatment group in improving the clinical indicators of ankylosing spondylitis, no significant differences in the short-term efficacy of biochemical the.4. index before and after drug withdrawal: the treatment group clinical index did not change significantly, no statistical significance (P0.05); changes of clinical indicators significantly control group, with statistical significance (P0.05), prompt treatment Long term effect of group than the control group. Conclusion: 1. moxibustion combined with traditional Chinese medicine therapy in patients with ankylosing spondylitis (kidney yang deficiency) clinical symptoms, signs and biochemical indicators better than the pure traditional Chinese medicine therapy.2. moxibustion combined with traditional Chinese medicine therapy in the treatment of ankylosing spondylitis (kidney yang deficiency) the long-term curative effect is better than pure Chinese medicine therapy.

【学位授予单位】：辽宁中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R246.1

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