清热化湿，利胆和胃法治疗胆胃郁热型胆汁反流性胃炎的临床疗效研究

发布时间：2018-04-06 05:22

本文选题：胆汁反流性胃炎　切入点：胆胃郁热　出处：《南京中医药大学》2017年硕士论文

【摘要】：目的:清热化湿、利胆和胃法治疗胆胃郁热型胆汁反流性胃炎(BRG)的临床疗效观察。方法:将60例胆胃郁热型胆汁反流性胃炎病例随机分为治疗组和对照组,两组各30例。病例收集自2016年4月至2016年12月期间来自江苏省中医院普内科及脾胃病科门诊和南京医科大学第二附属医院消化科门诊。治疗组口服柴胡陷胸汤加减治疗;对照组予枸橼酸莫沙必利联合铝碳酸镁片治疗。观察治疗前后两组中医症状改善情况,计算各症状积分、总积分并建立数据库,用SPSS19.0软件统计、对比两组治疗疗程(8周)后病情改善情况。结果:治疗后,治疗组治疗BRG所有症状均有改善;对照组除舌苔黄腻无明显改变外,其余主、次症状均有改善,两组之间比较,主要症状胃胺灼热疼痛、口苦而干的疗效实验组要优于对照组,次要症状而言,在改善反酸、心烦易怒、舌苔、脉象上治疗组的效果优于对照组,在改善暖气、不欲食上两组的效果无差异;总体疗效上,治疗组治愈2例,显效13例,有效13例,无效2例,30例痊愈率为6.6%,愈显率为50%,总有效率93.3%;对照组治愈1例,显效11例,有效16例,无效2例,30例痊愈率为3.3%,愈显率为40%,总有效率93.3%;两组愈显率及有效率均无统计学差异,两组疗效均可,但在总体症状改善程度上,治疗者优于对照组。结论:运用清热化湿、利胆和胃法治疗胆胃郁热型胆汁反流性胃炎(BRG)有较好的临床疗效。
[Abstract]:Objective: to observe the clinical effect of clearing heat and removing dampness and promoting gallbladder and stomach in treating bile reflux gastritis of choledochal stagnation heat type.Methods: 60 cases of bile reflux gastritis were randomly divided into treatment group and control group with 30 cases in each group.Cases were collected from the Department of General Medicine and the Department of spleen and stomach Diseases of Jiangsu Provincial Hospital of traditional Chinese Medicine from April 2016 to December 2016 and from the Department of Digestive Medicine of the second affiliated Hospital of Nanjing Medical University.The treatment group was treated with bupleurum sinensis decoction and the control group was treated with mosapride citrate combined with magnesium aluminum carbonate tablets.Observe the improvement of TCM symptoms before and after treatment, calculate the symptom integral, total score and establish the database, use SPSS19.0 software statistics, compare the two groups after the treatment course of 8 weeks.Results: after treatment, all symptoms of BRG in the treatment group were improved, except for the yellowish tongue coating, the other main and secondary symptoms were improved in the control group.The experimental group with bitter and dry mouth was better than the control group, and the treatment group was superior to the control group in improving regurgitation, irritability, tongue coating and pulse, but there was no difference between the two groups in improving heating and not wanting to eat.In the treatment group, 2 cases were cured, 13 cases were markedly effective, 13 cases were effective, 30 cases were ineffective, the cure rate was 6.6, the effective rate was 50% and the total effective rate was 93.3%, while in the control group, 1 case was cured, 11 cases were effective and 16 cases were effective.The cure rate was 3.3%, the effective rate was 40%, and the total effective rate was 93.3.The two groups had no statistical difference in the effective rate and the effective rate, but the treatment group was superior to the control group in the improvement degree of the overall symptoms.Conclusion: the method of clearing away heat and removing dampness and promoting gallbladder and stomach is effective in treating bile reflux gastritis of choledochal stagnation heat type.
【学位授予单位】：南京中医药大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R259

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