小儿推拿治疗小儿厌食症的系统评价

发布时间：2018-04-06 05:25

  本文选题：推拿　切入点：小儿厌食　出处：《成都中医药大学》2016年硕士论文

【摘要】：目的：根据Cochrane协作网提供的方法,全面检索相关数据库中小儿推拿治疗小儿厌食症的临床随机对照试验。对纳入文献进行信息提取,评价文献质量,完成系统评价。明确小儿推拿治疗小儿厌食症的临床疗效及安全性。方法：参照Cochrane协作网工作手册标准,全面检索相关期刊论文(CNKI)、维普期刊全文数据库(VIP)、万方学术期刊全文数据库(WF)、中国生物医学文献数据库(CBM)、PubMed、Cochrane Library、Ovid Medline、EMbase、EBM。利用百度、搜狗等搜索引擎以及纳入文献的参考文献进行补充检索。检索时间限定为各数据库建库之日起至2016年1月31日止。2名评价员根据预先制定的纳入标准与排除标准对检索出的文献独立进行筛选。对最终纳入的文献提取相关信息并填入资料提取表中。本研究采用Cochrane协作网提供的Review Manager 5.3软件来完成统计分析,对小儿推拿治疗小儿厌食症的总有效率、痊愈率进行定量分析。采用GradeP rofiler3.6软件对证据质量进行分级。结果：完成筛选后共25篇文献被纳入,共纳入病例1954例,治疗组1011例,对照组943例。患儿年龄6个月至13岁,病程10天至8年。定量分析：临床有效率：小儿推拿vs补锌剂(RR=1.32,95%CI[1.19,1.48]);小儿推拿vs中成药(RR=1.18,95%CI[1.13,1.23])；小儿推拿vs新制藿香正气散(RR=0.97,95%CI[0.89,1.05]);痊愈率：小儿推拿vs补锌剂(RR=2.26,95%CI[1.48,3.45])；小儿推拿vs中成药(RR=I.50,95%CI[1.19,1.90])；小儿推拿vs新制藿香正气散(RR=1.20,95%CI[0.56,2.56]。定性分析：完成4项研究的临床有效率及痊愈率、8项研究的食量积分、3项研究的不良反应的定性分析。结论：小儿推拿与补锌剂对比,其临床有效率优于补锌剂,证据质量中级,具有一定的可靠性；小儿推拿治疗小儿厌食症痊愈率优于补锌剂,证据质量低级,结果应慎重对待。小儿推拿对照中成药,在临床有效率方面具有一定优势,证据质量为低级,结果应慎重对待；小儿推拿在痊愈率方面优于中成药,证据质量极低,结果可信性低。小儿推拿对照新制藿香正气散,在临床有效率与痊愈率方面均不具有优势,证据质量均为极低级,结果可靠性差。3项涉及安全性评价的试验均未有不良反应报道,提示小儿推拿疗法安全性较好,但纳入样本量较小,对临床参考性差。
[Abstract]:Objective: to search the clinical randomized controlled trial of infantile anorexia treated with massage in related database according to the method provided by Cochrane Cooperative Network.Carry on the information extraction, evaluate the quality of the literature and complete the systematic evaluation.To determine the clinical efficacy and safety of pediatric massage in the treatment of infantile anorexia.Methods: according to the standard of working manual of Cochrane collaboration Network, we searched the full text database of Chinese periodical (CNKI), WIP (WIP), WFN (full text database) of academic journals of Wanfang, and the database of Chinese biomedical literature (CBM): Cochrane Cochrane Library Ovid Medline and EMbase EBM.Methods: according to the standard of working manual of Cochrane cooperation network, we searched the full text database of Chinese periodical, Weip, WFX, and Chinese biomedical literature database.Baidu, Sogou and other search engines and into the literature into the reference for supplementary retrieval.The retrieval time was limited from the date of the establishment of each database to the end of January 31, 2016. 2 evaluators independently screened the retrieved documents according to the pre-established inclusion criteria and exclusion criteria.Extract the relevant information from the final documents and fill in the data extraction table.In this study, the total effective rate and cure rate of infantile anorexia were quantitatively analyzed by using Review Manager 5.3 software provided by Cochrane Cooperative Network.The quality of evidence was classified by GradeP rofiler3.6 software.Results: a total of 25 articles were included, including 1954 cases, 1011 cases in the treatment group and 943 cases in the control group.The children were aged from 6 months to 13 years and the course of disease ranged from 10 days to 8 years.瀹氶噺鍒嗘瀽:涓村簥鏈夋晥鐜，

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