强志散治疗多发性抽动症的临床疗效及对患儿自控能力的干预效应

发布时间：2018-04-09 21:00

本文选题：强志散　切入点：小儿多发性抽动症　出处：《山东中医药大学》2016年硕士论文

【摘要】：目的:观察强志散治疗小儿多发性抽动症(肾志不足证)的临床疗效和对患儿自控能力的干预效应,验证肾藏志理论对治疗本病的指导价值。方法:将符合纳入标准的60例多发性抽动症患儿按1:1的比例随机分为中药组和西药组,分别给予强志散免煎颗粒(中药组)和盐酸硫必利片(西药组)口服治疗。治疗24周,随访24周。观察两组治疗前后总疗效、抽动症状、中医证候和自控能力的疗效、不良反应和安全性、远期疗效。结果:1.两组抽动疗效比较,中药组和西药组总有效率分别为90%、73.33%,减分率分别为(64.35±21.34)%和(49.89±22.90)%,中药组治疗效果优于西药组。2.两组证候疗效比较,中药组和西药组总有效率分别为93.33%、76.67%,减分率分别为(60.82±16.62)%和(42.19±15.26)%,中药组治疗效果优于西药组。3.两组自控能力改善情况比较,中药组和西药组总有效率分别为96.67%、76.67%,增分率分别为(65.70±15.10)%和(41.19±12.52)%,中药组疗效亦优于西药组。4.两组在不良反应率和复发率的比较,中药组优于西药组;安全性比较无差别。结论:强志散治疗小儿多发性抽动症(肾志不足证)的临床疗效及自控能力改善情况优于盐酸硫必利片。
[Abstract]:Objective: to observe the clinical effect of Qiangzhi Powder in the treatment of children with multiple tic syndrome (deficiency of renal records) and its intervention effect on the ability of self-control in children, and to verify the guiding value of the theory of Kidney Zang Zhi in the treatment of this disease.Methods: sixty children with multiple tic syndrome were randomly divided into Chinese medicine group and western medicine group according to the 1:1 ratio, and were given oral treatment of Qiang Zhi San Fan-Jian granule (Chinese medicine group) and tiapride hydrochloride tablet (western medicine group), respectively.The patients were followed up for 24 weeks.The total curative effect, twitch symptom, TCM syndromes and self-control ability, adverse reaction and safety, and long term curative effect were observed before and after treatment.The result is 1: 1.The total effective rates of TCM group and western medicine group were 90% and 73.33, respectively. The reduction rates were 64.35 卤21.34% and 49.89 卤22.90%, respectively. The curative effect of TCM group was better than that of western medicine group.The total effective rates of TCM group and western medicine group were 93.330.67 and 76.67, respectively. The reduction rates were 60.82 卤16.62% and 42.19 卤15.26%, respectively. The therapeutic effect of TCM group was better than that of western medicine group (.3).The total effective rate of the Chinese medicine group and the western medicine group were 96.67 and 76.67, respectively. The increase rates were 65.70 卤15.10% and 41.19 卤12.52%, respectively. The curative effect of the traditional Chinese medicine group was better than that of the western medicine group (.4).The adverse reaction rate and recurrence rate of the two groups were better than that of the western medicine group.Conclusion: Qiangzhi Powder is superior to Tiapride Hydrochloride tablets in the treatment of children with multiple tic syndrome.
【学位授予单位】：山东中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R277.7

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