基于数据挖掘探析名老中医余国友治疗胃肠功能衰竭用药规律

发布时间：2018-04-15 06:08

本文选题：余国友 + 胃肠功能衰竭　；参考：《中国中药杂志》2017年19期

【摘要】：胃肠功能衰竭是一种严重的全身性炎症反应,常并发多脏器功能不全综合征,中西医结合治疗具有较好的疗效。该研究收集名老中医余国友主任医师中医药治疗89例胃肠功能衰竭的175张处方,通过数据挖掘探析、统计其中药及中药类别频数、频率,采用系统聚类方法分析其用药规律,总结余老的常用药物及处方。研究结果显示药物使用频次前3位的是厚朴、枳实、大黄,均为小承气汤的组成成分;使用中药中以补虚药、理气药、清热药、化痰药、化湿药为最常用类别,补虚药里又以占比达2/3的补气药为主;同时挖掘出新处方和新的药物组合,可作为临床用药参考。研究结果表明,余老临床辨证胃肠功能衰竭多以脾胃气虚为本,以热毒、血瘀、气滞、湿阻为标,论治胃肠功能衰竭常以健脾、理气、泻下通腑为主,依证配合化瘀解毒、化湿利浊、清热化痰等方药,辨证施治,随症加减,在治疗过程中重视"胃气"的调养和胃肠功能的恢复。
[Abstract]:Gastrointestinal failure is a severe systemic inflammatory reaction, often complicated with multiple organ dysfunction syndrome.This study collected 175 prescriptions for 89 cases of gastrointestinal failure treated by Yu Guoyou, chief physician of old Chinese medicine. Through data mining, the frequency and frequency of traditional Chinese medicine and its categories were counted, and the law of drug use was analyzed by systematic cluster method.General balance of old common drugs and prescriptions.The results showed that the top three drugs were Magnolia officinalis, Fructus Aurantii and Rhubarb, all of which were components of Xiaocheng Qi decoction.At the same time, the new prescription and the new combination of drugs can be used as a reference for clinical use.The results show that the syndrome differentiation of Yu Lao is based on deficiency of spleen and stomach qi, heat toxin, blood stasis, qi stagnation and dampness obstruction as the standard. The main treatment of gastrointestinal failure is to invigorate spleen, regulate qi, and purge the lower and lower entrails, and detoxify blood stasis and detoxify according to syndrome.The prescription of removing dampness and removing turbidity, clearing away heat and resolving phlegm, and so on, are treated with syndrome differentiation, plus or minus with syndrome, and the recuperation of "stomach qi" and the recovery of gastrointestinal function are emphasized in the course of treatment.
【作者单位】：浙江大学医学院附属第一医院;浙江中医药大学;
【基金】：全国余国友名老中医药专家传承工作室建设项目(2016) 浙江省中医药科学研究基金项目(2016ZA114)
【分类号】：R249;R259

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