情志“思”“恐”对胚胎停育史患者再妊娠结局影响的临床观察

发布时间：2018-04-18 07:39

本文选题：胚胎停育 + 焦虑　；参考：《黑龙江中医药大学》2017年硕士论文

【摘要】：目的:观察有胚胎停育史患者再次妊娠早期情志"思""恐"与血HCG增长速度及妊娠结局之间的关系,从情志角度探讨影响胚胎生长发育的可能危险因素;评价中药联合心理疗法对妊娠结局的影响程度。方法:收集2015年9月至2016年12月于黑龙江中医药大学附属第一医院妇科门诊就诊的具有胚胎停育史并再次妊娠的患者,并对这些患者进行焦虑情况测评调查,收集符合入组标准的患者60例。治疗组30例,采用中药联合心理治疗;对照组30例,采用单纯中药治疗。观察干预前后患者血HCG增长速度、焦虑状态改变情况及两组患者妊娠结局。结果:1.具有胚胎停育史的焦虑孕妇孕早期血HCG增长速度明显低于正常水平;2.干预后两组患者的SAS评分较干预前有所改善,差异有统计学意义;3.干预后患者的SAS评分与血HCG增长速度及妊娠结局呈负向相关;4.干预后治疗组SAS评分下降幅度及血HCG增长速度明显大于对照组,差异有统计学意义;5.干预后治疗组的妊娠结局明显优于对照组,差异有统计学意义。结论:1.情志可以影响胚胎停育患者再次妊娠早期血HCG的增长;2.情志"思" "恐"有可能是有胚胎停育史患者再妊娠结局的影响因素之一;3.中药调志安胎饮联合心理疗法可明显改善患者的焦虑状态,提高妊娠成功率。
[Abstract]:Objective: to observe the relationship between early pregnancy mood "thought" and blood HCG growth rate and pregnancy outcome in patients with history of embryo suspension, and to explore the possible risk factors affecting embryo growth and development from the emotional point of view.To evaluate the effect of traditional Chinese medicine combined with psychotherapy on pregnancy outcome.Methods: from September 2015 to December 2016, the patients who had the history of embryo suspension and re pregnancy were collected from the gynecological outpatient clinic of the first affiliated Hospital of Heilongjiang University of traditional Chinese Medicine, and the anxiety status of these patients was investigated.A total of 60 patients who met the admission criteria were collected.The treatment group (30 cases) was treated with traditional Chinese medicine combined with psychological therapy, and the control group (30 cases) with traditional Chinese medicine alone.Blood HCG growth rate, anxiety state and pregnancy outcome were observed before and after intervention.The result is 1: 1.The growth rate of serum HCG in anxious pregnant women with a history of fetal arrest was significantly lower than that of normal pregnant women (2. 2%) in the first trimester of pregnancy.After intervention, the SAS scores of the two groups were improved compared with those before the intervention, and the difference was statistically significant (P < 0.05).After intervention, the SAS score was negatively correlated with the blood HCG growth rate and pregnancy outcome.After intervention, the decrease of SAS score and the increase rate of blood HCG in the treatment group were significantly higher than those in the control group (P < 0.05).The pregnancy outcome of the treatment group was significantly better than that of the control group after intervention, and the difference was statistically significant.Conclusion 1.Emotion can affect the increase of HCG in the early pregnancy of embryo suspensions.Emotion "thinking" and "fear" may be one of the influencing factors of re-pregnancy outcome in patients with history of embryo termination.Traditional Chinese medicine Tiaozhi Antian decoction combined with psychotherapy can obviously improve the anxiety state of the patients and increase the success rate of pregnancy.
【学位授予单位】：黑龙江中医药大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R271.9

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